maitre de conférence, université de rennes 1
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Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes
K Mahéo, F Morel, S Langouët, H Kramer, E Le Ferrec, B Ketterer, ...
Cancer Research 57 (17), 3649-3652, 1997
In Vitro Models of the Intestinal Barrier: The Report and Recommendations of ECVAM Workshop 46,
E Le Ferrec, C Chesne, P Artusson, D Brayden, G Fabre, P Gires, ...
Alternatives to laboratory animals 29 (6), 649-668, 2001
Polycyclic aromatic hydrocarbons inhibit differentiation of human monocytes into macrophages
J van Grevenynghe, S Rion, E Le Ferrec, M Le Vee, L Amiot, R Fauchet, ...
The Journal of Immunology 170 (5), 2374-2381, 2003
Analysis of drug transporter expression in human intestinal Caco‐2 cells by real‐time PCR
N Maubon, M Le Vee, L Fossati, M Audry, E Le Ferrec, S Bolze, O Fardel
Fundamental & clinical pharmacology 21 (6), 659-663, 2007
The human glutathione transferase alpha locus: genomic organization of the gene cluster and functional characterization of the genetic polymorphism in the hGSTA1 promoter
F Morel, C Rauch, B Coles, E Le Ferrec, A Guillouzo
Pharmacogenetics and Genomics 12 (4), 277-286, 2002
Polycyclic aromatic hydrocarbons affect functional differentiation and maturation of human monocyte-derived dendritic cells
B Laupeze, L Amiot, L Sparfel, E Le Ferrec, R Fauchet, O Fardel
The Journal of Immunology 168 (6), 2652-2658, 2002
ERK-dependent induction of TNFα expression by the environmental contaminant benzo (a) pyrene in primary human macrophages
V Lecureur, E Le Ferrec, M N’diaye, M Le Vee, C Gardyn, D Gilot, ...
FEBS letters 579 (9), 1904-1910, 2005
Interleukin-8 induction by the environmental contaminant benzo (a) pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation
N Podechard, V Lecureur, E Le Ferrec, I Guenon, L Sparfel, D Gilot, ...
Toxicology letters 177 (2), 130-137, 2008
Aryl hydrocarbon receptor-and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo [a] pyrene
M N'Diaye, E Le Ferrec, D Lagadic-Gossmann, S Corre, D Gilot, ...
Journal of Biological Chemistry 281 (29), 19906-19915, 2006
Transcriptional induction of CYP1A1 by oltipraz in human Caco-2 cells is aryl hydrocarbon receptor-and calcium-dependent
E Le Ferrec, D Lagadic-Gossmann, C Rauch, C Bardiau, K Maheo, ...
Journal of Biological Chemistry 277 (27), 24780-24787, 2002
Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIα pathway
P Monteiro, D Gilot, E Le Ferrec, C Rauch, D Lagadic-Gossmann, ...
Molecular Pharmacology 73 (3), 769-777, 2008
Induction of intracellular calcium concentration by environmental benzo (a) pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1, 4, 5-trisphosphate …
A Mayati, N Levoin, H Paris, M N'Diaye, A Courtois, P Uriac, ...
Journal of Biological Chemistry 287 (6), 4041-4052, 2012
Differential regulation of multidrug resistance-associated protein 2 (MRP2) and cytochromes P450 2B1/2 and 3A1/2 in phenobarbital-treated hepatocytes
A Courtois, L Payen, E Le Ferrec, GL Scheffer, Y Trinquart, A Guillouzo, ...
Biochemical pharmacology 63 (2), 333-341, 2002
NPC1 repression contributes to lipid accumulation in human macrophages exposed to environmental aryl hydrocarbons
N Podechard, E Le Ferrec, A Rebillard, O Fardel, V Lecureur
Cardiovascular research 82 (2), 361-370, 2009
AhR-and c-maf-dependent induction of β7-integrin expression in human macrophages in response to environmental polycyclic aromatic hydrocarbons
P Monteiro, D Gilot, E Le Ferrec, V Lecureur, M N’diaye, M Le Vee, ...
Biochemical and biophysical research communications 358 (2), 442-448, 2007
Microalgal carotenoids and phytosterols regulate biochemical mechanisms involved in human health and disease prevention
M Le Goff, E Le Ferrec, C Mayer, V Mimouni, D Lagadic-Gossmann, ...
Biochimie 167, 106-118, 2019
Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway (s)
BC Brinchmann, T Skuland, MH Rambøl, K Szoke, JE Brinchmann, ...
Particle and fibre toxicology 15 (1), 1-17, 2018
Calcium signaling and β2-adrenergic receptors regulate 1-nitropyrene induced CXCL8 responses in BEAS-2B cells
A Mayati, E Le Ferrec, JA Holme, O Fardel, D Lagadic-Gossmann, ...
Toxicology in Vitro 28 (6), 1153-1157, 2014
Benzo [a] pyrene-induced DNA damage associated with mutagenesis in primary human activated T lymphocytes
M Liamin, E Boutet-Robinet, EL Jamin, M Fernier, L Khoury, B Kopp, ...
Biochemical pharmacology 137, 113-124, 2017
Aryl hydrocarbon receptor‐independent up‐regulation of intracellular calcium concentration by environmental polycyclic aromatic hydrocarbons in human endothelial HMEC‐1 cells
A Mayati, E Le Ferrec, D Lagadic‐Gossmann, O Fardel
Environmental toxicology 27 (9), 556-562, 2012
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