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Nathaniel R West
Nathaniel R West
Verified email at gene.com
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Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease
NR West, AN Hegazy, BMJ Owens, SJ Bullers, B Linggi, S Buonocore, ...
Nature medicine 23 (5), 579-589, 2017
6732017
Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer
NR West, K Milne, PT Truong, N Macpherson, BH Nelson, PH Watson
Breast cancer research 13, 1-13, 2011
4382011
Emerging cytokine networks in colorectal cancer
NR West, S McCuaig, F Franchini, F Powrie
Nature Reviews Immunology 15 (10), 615-629, 2015
3832015
Tumour-infiltrating FOXP3+ lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer
NR West, SE Kost, SD Martin, K Milne, RJ Deleeuw, BH Nelson, ...
British journal of cancer 108 (1), 155-162, 2013
3062013
Circulating and tissue-resident CD4+ T cells with reactivity to intestinal microbiota are abundant in healthy individuals and function is altered during inflammation
AN Hegazy, NR West, MJT Stubbington, E Wendt, KIM Suijker, A Datsi, ...
Gastroenterology 153 (5), 1320-1337. e16, 2017
2942017
ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation
C Pearson, EE Thornton, B McKenzie, AL Schaupp, N Huskens, T Griseri, ...
eLife 5, e10066, 2016
2082016
Oncostatin-M promotes phenotypic changes associated with mesenchymal and stem cell-like differentiation in breast cancer
NR West, JI Murray, PH Watson
Oncogene 33 (12), 1485-1494, 2014
1142014
Coordination of immune-stroma crosstalk by IL-6 family cytokines
NR West
Frontiers in immunology 10, 457179, 2019
1032019
S100A7 (psoriasin) is induced by the proinflammatory cytokines oncostatin-M and interleukin-6 in human breast cancer
NR West, PH Watson
Oncogene 29 (14), 2083-2092, 2010
952010
Oncostatin M suppresses oestrogen receptor-a expression and is associated with poor outcome in human breast cancer
NR West, LC Murphy, PH Watson
Endocr Relat Cancer 19 (2), 181-195, 2012
922012
Immunotherapy not working? Check your microbiota
NR West, F Powrie
Cancer cell 28 (6), 687-689, 2015
642015
Foxp3+ T reg cells control psoriasiform inflammation by restraining an IFN-I–driven CD8+ T cell response
K Stockenhuber, AN Hegazy, NR West, NE Ilott, A Stockenhuber, ...
Journal of Experimental Medicine 215 (8), 1987-1998, 2018
622018
The autophagy protein LC3A correlates with hypoxia and is a prognostic marker of patient survival in clear cell ovarian cancer
JE Spowart, KN Townsend, H Huwait, S Eshragh, NR West, JN Ries, ...
The Journal of pathology 228 (4), 437-447, 2012
612012
The oncostatin M‐stromal cell axis in health and disease
NR West, BMJ Owens, AN Hegazy
Scandinavian Journal of Immunology 88 (3), e12694, 2018
572018
Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis
G Ryzhakov, NR West, F Franchini, S Clare, NE Ilott, SN Sansom, ...
Nature Communications 9 (1), 3797, 2018
552018
Jab1 is a target of EGFR signaling in ERα-negative breast cancer
J Wang, RO Barnes, NR West, M Olson, JE Chu, PH Watson
Breast cancer research 10, 1-11, 2008
442008
CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy
MA Huseni, L Wang, JE Klementowicz, K Yuen, B Breart, C Orr, L Liu, Y Li, ...
Cell Reports Medicine 4 (1), 2023
382023
Identification and characterization of binding sites on S100A7, a participant in cancer and inflammation pathways
R León, JI Murray, G Cragg, B Farnell, NR West, TCS Pace, PH Watson, ...
Biochemistry 48 (44), 10591-10600, 2009
342009
Markers of T cell infiltration and function associate with favorable outcome in vascularized high-grade serous ovarian carcinoma
KN Townsend, JE Spowart, H Huwait, S Eshragh, NR West, MA Elrick, ...
PloS one 8 (12), e82406, 2013
312013
The interleukin 22 pathway interacts with mutant KRAS to promote poor prognosis in colon cancer
S McCuaig, D Barras, EH Mann, M Friedrich, SJ Bullers, A Janney, ...
Clinical Cancer Research 26 (16), 4313-4325, 2020
302020
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