The NLRP3–inflammasome as a sensor of organelle dysfunction PI Seoane, B Lee, C Hoyle, S Yu, G Lopez-Castejon, M Lowe, D Brough Journal of Cell Biology 219 (12), e202006194, 2020 | 93 | 2020 |
Zinc status alters Alzheimer's disease progression through NLRP3-dependent inflammation J Rivers-Auty, VS Tapia, CS White, MJD Daniels, S Drinkall, PT Kennedy, ... Journal of Neuroscience 41 (13), 3025-3038, 2021 | 52 | 2021 |
Small, Thin Graphene Oxide Is Anti-inflammatory Activating Nuclear Factor Erythroid 2-Related Factor 2 via Metabolic Reprogramming C Hoyle, J Rivers-Auty, E Lemarchand, S Vranic, E Wang, M Buggio, ... ACS nano 12 (12), 11949-11962, 2018 | 48 | 2018 |
The effect of bisphosphonate treatment on osteoclast precursor cells in postmenopausal osteoporosis: The TRIO study F Gossiel, C Hoyle, EV McCloskey, KE Naylor, J Walsh, N Peel, R Eastell Bone 92, 94-99, 2016 | 35 | 2016 |
Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages C Hoyle, JP Green, SM Allan, D Brough, E Lemarchand Immunology 165 (4), 460-480, 2022 | 34 | 2022 |
Disruptions in endocytic traffic contribute to the activation of the NLRP3 inflammasome B Lee, C Hoyle, R Wellens, JP Green, F Martin-Sanchez, DM Williams, ... Science Signaling 16 (773), eabm7134, 2023 | 16 | 2023 |
Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture C Hoyle, E Redondo‐Castro, J Cook, TC Tzeng, SM Allan, D Brough, ... Immunology 161 (1), 39-52, 2020 | 13 | 2020 |
NLRP3 activation in response to disrupted endocytic traffic B Lee, C Hoyle, JP Green, R Wellens, F Martin-Sanchez, D Williams, ... bioRxiv, 2021.09. 15.460426, 2021 | 6 | 2021 |
The comparable tumour microenvironment in sporadic and NF2-related schwannomatosis vestibular schwannoma GE Gregory, AP Jones, MJ Haley, C Hoyle, LAH Zeef, IH Lin, DJ Coope, ... Brain Communications 5 (4), fcad197, 2023 | 3 | 2023 |
Itaconate and fumarate derivatives exert a dual inhibitory effect on canonical NLRP3 activation in macrophages and microglia C Hoyle, JP Green, SM Allan, D Brough, E Lemarchand bioRxiv, 2021.02. 01.429180, 2021 | 1 | 2021 |
Brazilin is a natural product inhibitor of the NLRP3 inflammasome E McMahon, S El-Sayed, J Green, C Hoyle, L Fitzpatrick, EV Jones, ... Iscience 27 (2), 2024 | | 2024 |
Proximity labelling and evolutionary evidence reveal insights into IL-1α nuclear networks and function R Wellens, VS Tapia, H Bennett, A Adamson, J Rivers-Auty, JP Green, ... bioRxiv, 2023.06. 26.546506, 2023 | | 2023 |
Cellular signaling, molecular activation, and regulation of the NLRP3 inflammasome R Wellens, B Matchett, D Brough, C Hoyle Inflammasome Biology, 51-65, 2023 | | 2023 |
Contribution of inflammasomes to ischaemic stroke E Lemarchand, C Hoyle, J Barrington, G Coutts, SM Allan, D Brough JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 37, 472-472, 2017 | | 2017 |
The effect of bisphosphonate treatment on osteoclast precursor cells in postmenopausal women with rsteoporosis: The TRIO study F Gossiel, C Hoyle, E McCloskey, J Walsh, N Peel, R Eastell Bone Abstracts 3, 2014 | | 2014 |