Michele Mazzanti
Michele Mazzanti
Cellular Physiology Professor, University of Milan, Italy
Verified email at unimi.it
TitleCited byYear
Properties of the hyperpolarizing‐activated current (if) in cells isolated from the rabbit sino‐atrial node.
D DiFrancesco, A Ferroni, M Mazzanti, C Tromba
The Journal of physiology 377 (1), 61-88, 1986
5201986
Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-Å resolution
SJ Harrop, MZ DeMaere, WD Fairlie, T Reztsova, SM Valenzuela, ...
Journal of Biological Chemistry 276 (48), 44993-45000, 2001
2052001
The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition
DR Littler, SJ Harrop, WD Fairlie, LJ Brown, GJ Pankhurst, S Pankhurst, ...
Journal of Biological Chemistry 279 (10), 9298-9305, 2004
1732004
Ion channels in the nuclear envelope
M Mazzanti, LJ DeFelice, J Cohen, H Malter
Nature 343 (6260), 764, 1990
1721990
Electrical dimension of the nuclear envelope
M Mazzanti, JO Bustamante, H Oberleithner
Physiological Reviews 81 (1), 1-19, 2001
1672001
The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle
SM Valenzuela, M Mazzanti, R Tonini, MR Qiu, K Warton, EA Musgrove, ...
The Journal of physiology 529 (3), 541-552, 2000
1482000
The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins?
DR Littler, SJ Harrop, SC Goodchild, JM Phang, AV Mynott, L Jiang, ...
FEBS letters 584 (10), 2093-2101, 2010
1202010
Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in …
K Warton, R Tonini, WD Fairlie, JM Matthews, SM Valenzuela, MR Qiu, ...
Journal of Biological Chemistry 277 (29), 26003-26011, 2002
1182002
Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells
R Tonini, A Ferroni, SM Valenzuela, K Warton, TJ Campbell, SN Breit, ...
The FASEB Journal 14 (9), 1171-1178, 2000
1102000
CLIC1 function is required for β-amyloid-induced generation of reactive oxygen species by microglia
RH Milton, R Abeti, S Averaimo, S DeBiasi, L Vitellaro, L Jiang, ...
Journal of Neuroscience 28 (45), 11488-11499, 2008
1082008
Crystal structure of the soluble form of the redox‐regulated chloride ion channel protein CLIC4
DR Littler, NN Assaad, SJ Harrop, LJ Brown, GJ Pankhurst, P Luciani, ...
The FEBS journal 272 (19), 4996-5007, 2005
1052005
Involvement of the intracellular ion channel CLIC1 in microglia-mediated β-amyloid-induced neurotoxicity
G Novarino, C Fabrizi, R Tonini, MA Denti, F Malchiodi-Albedi, GM Lauro, ...
Journal of Neuroscience 24 (23), 5322-5330, 2004
1052004
ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress
A Kumar, M Mazzanti, M Mistrik, M Kosar, GV Beznoussenko, AA Mironov, ...
Cell 158 (3), 633-646, 2014
1012014
Chloride intracellular channel 1 (CLIC1): Sensor and effector during oxidative stress
S Averaimo, RH Milton, MR Duchen, M Mazzanti
FEBS letters 584 (10), 2076-2084, 2010
872010
Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current
M Gritti, R Würth, M Angelini, F Barbieri, M Peretti, E Pizzi, A Pattarozzi, ...
Oncotarget 5 (22), 11252, 2014
812014
Biochemical and electrophysiological studies on the mechanism of action of PNU-151774E, a novel antiepileptic compound
P Salvati, R Maj, C Caccia, MA Cervini, MG Fornaretto, E Lamberti, ...
Journal of pharmacology and experimental therapeutics 288 (3), 1151-1159, 1999
741999
Chloride channels in the nuclear membrane
L Tabares, M Mazzanti, DE Clapham
The Journal of membrane biology 123 (1), 49-54, 1991
681991
Drug-repositioning opportunities for cancer therapy: novel molecular targets for known compounds
R Wuerth, S Thellung, A Bajetto, M Mazzanti, T Florio, F Barbieri
Drug discovery today 21 (1), 190-199, 2016
652016
Chloride channels in cancer: focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets
M Peretti, M Angelini, N Savalli, T Florio, SH Yuspa, M Mazzanti
Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (10), 2523-2531, 2015
642015
Structure of the Janus protein human CLIC2
BA Cromer, MA Gorman, G Hansen, JJ Adams, M Coggan, DR Littler, ...
Journal of molecular biology 374 (3), 719-731, 2007
642007
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