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Gibran Hemani
Gibran Hemani
Verified email at bristol.ac.uk - Homepage
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The MR-Base platform supports systematic causal inference across the human phenome
G Hemani, J Zheng, B Elsworth, KH Wade, V Haberland, D Baird, ...
elife 7, e34408, 2018
41962018
Mendelian randomization: genetic anchors for causal inference in epidemiological studies
G Davey Smith, G Hemani
Human molecular genetics 23 (R1), R89-R98, 2014
27052014
Defining the role of common variation in the genomic and biological architecture of adult human height
AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ...
Nature genetics 46 (11), 1173-1186, 2014
20702014
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
DM Howard, MJ Adams, TK Clarke, JD Hafferty, J Gibson, M Shirali, ...
Nature neuroscience 22 (3), 343-352, 2019
18062019
Orienting the causal relationship between imprecisely measured traits using GWAS summary data
G Hemani, K Tilling, G Davey Smith
PLoS genetics 13 (11), e1007081, 2017
11762017
LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic …
J Zheng, AM Erzurumluoglu, BL Elsworth, JP Kemp, L Howe, PC Haycock, ...
Bioinformatics 33 (2), 272-279, 2017
9192017
Evaluating the potential role of pleiotropy in Mendelian randomization studies
G Hemani, J Bowden, G Davey Smith
Human molecular genetics 27 (R2), R195-R208, 2018
8952018
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
J Yang, A Bakshi, Z Zhu, G Hemani, AAE Vinkhuyzen, SH Lee, ...
Nature genetics 47 (10), 1114-1120, 2015
8442015
Collider bias undermines our understanding of COVID-19 disease risk and severity
GJ Griffith, TT Morris, MJ Tudball, A Herbert, G Mancano, L Pike, ...
Nature communications 11 (1), 1-12, 2020
7532020
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
Nature genetics 53 (9), 1300-1310, 2021
7122021
Improved heritability estimation from genome-wide SNPs
D Speed, G Hemani, MR Johnson, DJ Balding
The American Journal of Human Genetics 91 (6), 1011-1021, 2012
7062012
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
A Xue, Y Wu, Z Zhu, F Zhang, KE Kemper, Z Zheng, L Yengo, ...
Nature communications 9 (1), 2941, 2018
6872018
Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score
Q Zhao, J Wang, G Hemani, J Bowden, DS Small
5962020
Systematic identification of genetic influences on methylation across the human life course
TR Gaunt, HA Shihab, G Hemani, JL Min, G Woodward, O Lyttleton, ...
Genome biology 17, 1-14, 2016
5792016
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ...
Nature genetics 51 (2), 245-257, 2019
5772019
Recent developments in Mendelian randomization studies
J Zheng, D Baird, MC Borges, J Bowden, G Hemani, P Haycock, ...
Current epidemiology reports 4, 330-345, 2017
5322017
Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique
FP Hartwig, NM Davies, G Hemani, G Davey Smith
International journal of epidemiology 45 (6), 1717-1726, 2016
5082016
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
BioRxiv, 447367, 2018
4892018
Association between telomere length and risk of cancer and non-neoplastic diseases: a Mendelian randomization study
PC Haycock, S Burgess, A Nounu, J Zheng, GN Okoli, J Bowden, ...
JAMA oncology 3 (5), 636-651, 2017
4842017
Detecting epistasis in human complex traits
WH Wei, G Hemani, CS Haley
Nature Reviews Genetics 15 (11), 722-733, 2014
4652014
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Articles 1–20