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Kevin Christopher Ludwig
Kevin Christopher Ludwig
Verified email at uni-bonn.de
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Year
Ca2+-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids
F Grein, A Müller, KM Scherer, X Liu, KC Ludwig, A Klöckner, M Strach, ...
Nature communications 11 (1), 1455, 2020
1732020
Host defense peptides: Dual antimicrobial and immunomodulatory action
M Drayton, JP Deisinger, KC Ludwig, N Raheem, A Müller, T Schneider, ...
International Journal of Molecular Sciences 22 (20), 11172, 2021
622021
The lasso peptide siamycin-I targets lipid II at the Gram-positive cell surface
S Tan, KC Ludwig, A Müller, T Schneider, JR Nodwell
ACS Chemical Biology 14 (5), 966-974, 2019
392019
An antibiotic from an uncultured bacterium binds to an immutable target
R Shukla, AJ Peoples, KC Ludwig, S Maity, MGN Derks, S De Benedetti, ...
Cell 186 (19), 4059-4073. e27, 2023
222023
Biosynthesis and mechanism of action of the cell wall targeting antibiotic hypeptin
DA Wirtz, KC Ludwig, M Arts, CE Marx, S Krannich, P Barac, S Kehraus, ...
Angewandte Chemie International Edition 60 (24), 13579-13586, 2021
222021
Steroids originating from bacterial bile acid degradation affect Caenorhabditis elegans and indicate potential risks for the fauna of manured soils
MN Mendelski, R Dölling, FM Feller, D Hoffmann, L Ramos Fangmeier, ...
Scientific Reports 9 (1), 11120, 2019
182019
A novel steroid-coenzyme A ligase from Novosphingobium sp. strain Chol11 is essential for an alternative degradation pathway for bile salts
O Yücel, J Holert, KC Ludwig, S Thierbach, B Philipp
Applied and Environmental Microbiology 84 (1), e01492-17, 2018
112018
THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates
E Reithuber, T Wixe, KC Ludwig, A Müller, H Uvell, F Grein, AEG Lindgren, ...
Proceedings of the National Academy of Sciences 118 (47), e2108244118, 2021
72021
Ca (2+)-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids. Nat Commun 2020; 11: 1455
F Grein, A Müller, KM Scherer, X Liu, KC Ludwig, A Klöckner
Epub 2020/03/21. doi: 10.1038/s41467-020-15257-1 32193379, 0
6
Impacts of NaHCO3 on β-Lactam Binding to PBP2a Protein Variants Associated with the NaHCO3-Responsive versus NaHCO3-Non-Responsive Phenotypes
SC Ersoy, LC Chan, MR Yeaman, HF Chambers, RA Proctor, KC Ludwig, ...
Antibiotics 11 (4), 462, 2022
52022
Investigations on the Degradation of the Bile Salt Cholate via the 9,10-Seco-Pathway Reveals the Formation of a Novel Recalcitrant Steroid Compound by a Side Reaction in …
FM Feller, S Eilebrecht, R Nedielkov, O Yücel, J Alvincz, G Salinas, ...
Microorganisms 9 (10), 2146, 2021
12021
An antibiotic from an uncultured bacterium binds to an immutable target
K Nieselt, R Shukla, AJ Peoples, KC Ludwig, S Maity, MGN Derks, ...
Cell 186 (19), 2023
2023
A new antibiotic from an uncultured bacterium binds to an immutable target
R Shukla, AJ Peoples, KC Ludwig, S Maity, MGN Derks, S de Benedetti, ...
bioRxiv, 2023
2023
Lipid II-binding antibiotics–differential antibiotic activities beyond sequestration of the central peptidoglycan precursor
KC Ludwig
Universitäts-und Landesbibliothek Bonn, 2023
2023
THCz
E Reithuber, T Wixe, KC Ludwig, A Müller, H Uvell, F Grein, AEG Lindgren, ...
Proceedings of the National Academy of Sciences of the United States of …, 2021
2021
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