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William Eimer
William Eimer
Genetics and Aging Research Unit, MGH/Harvard Medical School
Verified email at mgh.harvard.edu
Title
Cited by
Cited by
Year
Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease
DKV Kumar, SH Choi, KJ Washicosky, WA Eimer, S Tucker, J Ghofrani, ...
Science translational medicine 8 (340), 340ra72-340ra72, 2016
10162016
Alzheimer’s Disease-Associated β-amyloid Is Rapidly Seeded by Herpesviridae to Protect Against Brain Infection
WA Eimer, DK Vijaya Kumar, NKN Shanmugam, AS Rodriguez, T Mitchell, ...
Neuron 99 (1), 56-63.e3, 2018
6352018
Phosphorylation of the translation initiation factor eIF2α increases BACE1 levels and promotes amyloidogenesis
T O'Connor, KR Sadleir, E Maus, RA Velliquette, J Zhao, SL Cole, ...
Neuron 60 (6), 988-1009, 2008
4972008
Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation
WA Eimer, R Vassar
Molecular neurodegeneration 8, 1-12, 2013
3802013
APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease
KL Youmans, LM Tai, E Nwabuisi-Heath, L Jungbauer, T Kanekiyo, ...
Journal of Biological Chemistry 287 (50), 41774-41786, 2012
2802012
The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques
PC Kandalepas, KR Sadleir, WA Eimer, J Zhao, DA Nicholson, R Vassar
Acta neuropathologica 126, 329-352, 2013
2492013
Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody
KL Youmans, LM Tai, T Kanekiyo, WB Stine Jr, SC Michon, ...
Molecular neurodegeneration 7, 1-14, 2012
1742012
β-Site Amyloid Precursor Protein (APP)-cleaving Enzyme 1 (BACE1)-deficient Mice Exhibit a Close Homolog of L1 (CHL1) Loss-of-function Phenotype Involving Axon Guidance Defects*♦
B Hitt, SM Riordan, L Kukreja, WA Eimer, TW Rajapaksha, R Vassar
Journal of Biological Chemistry 287 (46), 38408-38425, 2012
1642012
Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level
KR Sadleir, WA Eimer, SL Cole, R Vassar
Molecular neurodegeneration 10, 1-16, 2015
1212015
The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb
TW Rajapaksha, WA Eimer, TC Bozza, R Vassar
Molecular neurodegeneration 6, 1-9, 2011
1162011
SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
AD Proal, MB VanElzakker, S Aleman, K Bach, BP Boribong, M Buggert, ...
Nature Immunology 24 (10), 1616-1627, 2023
532023
Alzheimer's disease: the potential therapeutic role of the natural antibiotic amyloid-β peptide
DKV Kumar, WA Eimer, RE Tanzi, RD Moir
Neurodegenerative disease management 6 (5), 345-348, 2016
452016
Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a …
KR Sadleir, WA Eimer, RJ Kaufman, P Osten, R Vassar
PLoS One 9 (7), e101643, 2014
382014
The spectrum of Trp mutants isolated as 5‐fluoroanthranilate‐resistant clones in Saccharomyces bayanus, S. mikatae and S. paradoxus
EW Jones, PB Berget, JM Burnette Iii, C Anderson, D Asafu‐Adjei, ...
Yeast 25 (1), 41-46, 2008
132008
Mutant allele-specific CRISPR disruption in DYT1 dystonia fibroblasts restores cell function
L Cruz, B György, PS Cheah, BP Kleinstiver, WA Eimer, SP Garcia, ...
Molecular Therapy-Nucleic Acids 21, 1-12, 2020
92020
Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease: Research outline and call for …
R Lathe, NM Schultek, BJ Balin, GD Ehrlich, LA Auber, G Perry, ...
Alzheimer's & Dementia 19 (11), 5209-5231, 2023
72023
Specificity of Toll-like receptor 2 and Dectin-1 signaling in CNS macrophages
DKV Kumar, WA Eimer, S Ramakrishnan
Journal of Neuroscience 35 (49), 16015-16017, 2015
62015
Erratum to: The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques
PC Kandalepas, KR Sadleir, WA Eimer, J Zhao, DA Nicholson, R Vassar
Acta Neuropathologica 126 (4), 623, 2013
22013
Author Correction: SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
AD Proal, MB VanElzakker, S Aleman, K Bach, BP Boribong, M Buggert, ...
Nature Immunology 24 (10), 1778-1778, 2023
12023
Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level
R Vassar, SL Cole, WA Eimer, KR Sadleir
2015
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