| Chloride regulates dynamic NLRP3-dependent ASC oligomerization and inflammasome priming JP Green, S Yu, F Martín-Sánchez, P Pelegrin, G Lopez-Castejon, ... Proceedings of the National Academy of Sciences 115 (40), E9371-E9380, 2018 | 161 | 2018 |
| USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation P Palazón‐Riquelme, JD Worboys, J Green, A Valera, F Martín‐Sánchez, ... EMBO reports 19 (10), e44766, 2018 | 139 | 2018 |
| Mechanisms of NLRP3 priming in inflammaging and age related diseases A Gritsenko, JP Green, D Brough, G Lopez-Castejon Cytokine & Growth Factor Reviews 55, 15-25, 2020 | 80 | 2020 |
| The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes VS Tapia, MJD Daniels, P Palazón-Riquelme, M Dewhurst, NM Luheshi, ... Journal of Biological Chemistry 294 (21), 8325-8335, 2019 | 75 | 2019 |
| Zinc status alters Alzheimer's disease progression through NLRP3-dependent inflammation J Rivers-Auty, VS Tapia, CS White, MJD Daniels, S Drinkall, PT Kennedy, ... Journal of Neuroscience 41 (13), 3025-3038, 2021 | 53 | 2021 |
| Atheroprone flow activates inflammation via endothelial ATP-dependent P2X7-p38 signalling JP Green, C Souilhol, I Xanthis, L Martinez-Campesino, NP Bowden, ... Cardiovascular research 114 (2), 324-335, 2018 | 52 | 2018 |
| Inhibition of the NLRP3 inflammasome by HSP90 inhibitors S Nizami, K Arunasalam, J Green, J Cook, CB Lawrence, ... Immunology 162 (1), 84-91, 2021 | 39 | 2021 |
| Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages C Hoyle, JP Green, SM Allan, D Brough, E Lemarchand Immunology 165 (4), 460-480, 2022 | 34 | 2022 |
| LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation JP Green, T Swanton, LV Morris, LY El-Sharkawy, J Cook, S Yu, ... Elife 9, e59704, 2020 | 29 | 2020 |
| Disruptions in endocytic traffic contribute to the activation of the NLRP3 inflammasome B Lee, C Hoyle, R Wellens, JP Green, F Martin-Sanchez, DM Williams, ... Science Signaling 16 (773), eabm7134, 2023 | 17 | 2023 |
| Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification S Yu, J Green, R Wellens, G Lopez‐Castejon, D Brough The FEBS Journal 288 (10), 3186-3196, 2021 | 11 | 2021 |
| Selective inhibition of the K+ efflux sensitive NLRP3 pathway by Cl− channel modulation T Swanton, JA Beswick, H Hammadi, L Morris, D Williams, S De Cesco, ... Chemical Science 11 (43), 11720-11728, 2020 | 11 | 2020 |
| Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors L González-Cofrade, JP Green, I Cuadrado, Á Amesty, S Oramas-Royo, ... Bioorganic Chemistry 132, 106362, 2023 | 8 | 2023 |
| LRRC8A is dispensable for a variety of microglial functions and response to acute stroke JR Cook, AL Gray, E Lemarchand, I Schiessl, JP Green, MC Newland, ... Glia 70 (6), 1068-1083, 2022 | 7 | 2022 |
| Looking into the IL-1 of the storm: are inflammasomes the link between immunothrombosis and hyperinflammation in cytokine storm syndromes? TA Gleeson, E Nordling, C Kaiser, CB Lawrence, D Brough, JP Green, ... Discovery Immunology 1 (1), kyac005, 2022 | 7 | 2022 |
| Stroke induces early recurrent vascular events by inflammasome-dependent atherosclerotic plaque rupture J Cao, S Roth, S Zhang, A Kopczak, MK Georgakis, X Li, A Dutsch, ... BioRxiv, 2023.02. 01.526550, 2023 | 4 | 2023 |
| Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome JP Green, LY El-Sharkawy, S Roth, J Zhu, J Cao, AG Leach, A Liesz, ... Iscience 26 (5), 106758, 2023 | 3 | 2023 |
| Discovery of an AIM2 inflammasome inhibitor for the treatment of DNA-driven inflammatory disease JP Green, LY El-Sharkawy, S Roth, J Zhu, J Cao, AG Leach, A Liesz, ... bioRxiv, 2022.07. 28.501942, 2022 | 2 | 2022 |
| Itaconate and fumarate derivatives exert a dual inhibitory effect on canonical NLRP3 activation in macrophages and microglia C Hoyle, JP Green, SM Allan, D Brough, E Lemarchand bioRxiv, 2021.02. 01.429180, 2021 | 1 | 2021 |
| LRRC8A regulates hypotonicity-induced NLRP3 inflammasome activation JP Green, T Swanton, LV Morris, LY El-Sharkawy, J Cook, S Yu, ... BioRxiv, 2020.06. 11.146225, 2020 | 1 | 2020 |
