Janet Askari
Janet Askari
Verified email at manchester.ac.uk
Title
Cited by
Cited by
Year
Linking integrin conformation to function
JA Askari, PA Buckley, AP Mould, MJ Humphries
Journal of cell science 122 (2), 165-170, 2009
3712009
Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly
ER Horton, A Byron, JA Askari, DHJ Ng, A Millon-Frémillon, J Robertson, ...
Nature cell biology 17 (12), 1577-1587, 2015
3492015
Integrin-specific signaling pathways controlling focal adhesion formation and cell migration
Z Mostafavi-Pour, JA Askari, SJ Parkinson, PJ Parker, TTC Ng, ...
Journal of Cell Biology 161 (1), 155-167, 2003
2602003
Crystal structure of a heparin‐and integrin‐binding segment of human fibronectin
A Sharma, JA Askari, MJ Humphries, EY Jones, DI Stuart
The EMBO Journal 18 (6), 1468-1479, 1999
2331999
SHARPIN is an endogenous inhibitor of β1-integrin activation
JK Rantala, J Pouwels, T Pellinen, S Veltel, P Laasola, E Mattila, ...
Nature cell biology 13 (11), 1315-1324, 2011
2062011
Defining the topology of integrin α5β1-fibronectin interactions using inhibitory anti-α5 and anti-β1 monoclonal antibodies: Evidence that the synergy sequence of fibronectin is …
MJ Humphries, JA Askari, AP Mould, S Aota, KM Yamada, A Irie, ...
Journal of Biological Chemistry 272 (28), 17283-17292, 1997
2051997
Defining the topology of integrin α5β1-fibronectin interactions using inhibitory anti-α5 and anti-β1 monoclonal antibodies: Evidence that the synergy sequence of fibronectin is …
MJ Humphries, JA Askari, AP Mould, S Aota, KM Yamada, A Irie, ...
Journal of Biological Chemistry 272 (28), 17283-17292, 1997
2051997
Anti-integrin monoclonal antibodies
A Byron, JD Humphries, JA Askari, SE Craig, AP Mould, MJ Humphries
Journal of cell science 122 (22), 4009-4011, 2009
1792009
Identification of a novel anti‐integrin monoclonal antibody that recognises a ligand‐induced binding site epitope on the β1 subunit
AP Mould, AN Garratt, JA Askari, SK Akiyama, MJ Humphries
FEBS letters 363 (1-2), 118-122, 1995
1791995
Integrin alpha 4 beta 1-mediated melanoma cell adhesion and migration on vascular cell adhesion molecule-1 (VCAM-1) and the alternatively spliced IIICS region of fibronectin.
AP Mould, JA Askari, SE Craig, AN Garratt, J Clements, MJ Humphries
Journal of Biological Chemistry 269 (44), 27224-27230, 1994
1611994
Conformational Changes in the Integrin औA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement
AP Mould, SJ Barton, JA Askari, PA McEwan, PA Buckley, SE Craig, ...
Journal of Biological Chemistry 278 (19), 17028-17035, 2003
1542003
Integrin activation involves a conformational change in the α1 helix of the β subunit A-domain
AP Mould, JA Askari, S Barton, AD Kline, PA McEwan, SE Craig, ...
Journal of Biological Chemistry 277 (22), 19800-19805, 2002
1482002
Signal transduction via integrin adhesion complexes
JD Humphries, MR Chastney, JA Askari, MJ Humphries
Current opinion in cell biology 56, 14-21, 2019
1452019
The integrin adhesome network at a glance
ER Horton, JD Humphries, J James, MC Jones, JA Askari, MJ Humphries
Journal of cell science 129 (22), 4159-4163, 2016
1402016
A specific α5β1-integrin conformation promotes directional integrin translocation and fibronectin matrix formation
K Clark, R Pankov, MA Travis, JA Askari, AP Mould, SE Craig, P Newham, ...
Journal of cell science 118 (2), 291-300, 2005
1342005
Molecular Basis of Ligand Recognition by Integrin α5β1: I. Specificity of ligand binding is determined by amino acid sequences in the second and third NH2-terminal repeats of …
AP Mould, JA Askari, MJ Humphries
Journal of Biological Chemistry 275 (27), 20324-20336, 2000
1332000
Focal adhesions are sites of integrin extension
JA Askari, CJ Tynan, SED Webb, ML Martin-Fernandez, C Ballestrem, ...
Journal of Cell Biology 188 (6), 891-903, 2010
1222010
Competitive binding of vascular cell adhesion molecule-1 and the HepII/IIICS domain of fibronectin to the integrin alpha 4 beta 1.
R Makarem, P Newham, JA Askari, LJ Green, J Clements, M Edwards, ...
Journal of Biological Chemistry 269 (6), 4005-4011, 1994
1211994
Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis
AP Mould, EJH Symonds, PA Buckley, JG Grossmann, PA McEwan, ...
Journal of Biological Chemistry 278 (41), 39993-39999, 2003
1172003
Role of ADMIDAS cation-binding site in ligand recognition by integrin α5β1
AP Mould, SJ Barton, JA Askari, SE Craig, MJ Humphries
Journal of Biological Chemistry 278 (51), 51622-51629, 2003
1162003
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