Mass spectrometry of intact V-type ATPases reveals bound lipids and the effects of nucleotide binding M Zhou, N Morgner, NP Barrera, A Politis, SC Isaacson, D Matak-Vinković, ... Science 334 (6054), 380-385, 2011 | 305 | 2011 |
Charge-state dependent compaction and dissociation of protein complexes: insights from ion mobility and molecular dynamics Z Hall, A Politis, MF Bush, LJ Smith, CV Robinson Journal of the American Chemical Society 134 (7), 3429-3438, 2012 | 302 | 2012 |
Structure of the CRISPR interference complex CSM reveals key similarities with cascade C Rouillon, M Zhou, J Zhang, A Politis, V Beilsten-Edmands, G Cannone, ... Molecular cell 52 (1), 124-134, 2013 | 262 | 2013 |
Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump J Marcoux, SC Wang, A Politis, E Reading, J Ma, PC Biggin, M Zhou, ... Proceedings of the National Academy of Sciences 110 (24), 9704-9709, 2013 | 192 | 2013 |
A mass spectrometry–based hybrid method for structural modeling of protein complexes A Politis, F Stengel, Z Hall, H Hernández, A Leitner, T Walzthoeni, ... Nature methods 11 (4), 403-406, 2014 | 188 | 2014 |
Integrating ion mobility mass spectrometry with molecular modelling to determine the architecture of multiprotein complexes A Politis, AY Park, SJ Hyung, D Barsky, BT Ruotolo, CV Robinson PloS one 5 (8), e12080, 2010 | 159 | 2010 |
Structural modeling of heteromeric protein complexes from disassembly pathways and ion mobility-mass spectrometry Z Hall, A Politis, CV Robinson Structure 20 (9), 1596-1609, 2012 | 153 | 2012 |
Comparative cross-linking and mass spectrometry of an intact F-type ATPase suggest a role for phosphorylation C Schmidt, M Zhou, H Marriott, N Morgner, A Politis, CV Robinson Nature communications 4 (1), 1985, 2013 | 152 | 2013 |
Direct protein-lipid interactions shape the conformational landscape of secondary transporters C Martens, M Shekhar, AJ Borysik, AM Lau, E Reading, E Tajkhorshid, ... Nature communications 9 (1), 4151, 2018 | 140 | 2018 |
Subunit architecture of multiprotein assemblies determined using restraints from gas-phase measurements TL Pukala, BT Ruotolo, M Zhou, A Politis, R Stefanescu, JA Leary, ... Structure 17 (9), 1235-1243, 2009 | 134 | 2009 |
Interrogating membrane protein conformational dynamics within native lipid compositions E Reading, Z Hall, C Martens, T Haghighi, H Findlay, Z Ahdash, A Politis, ... Angewandte Chemie International Edition 56 (49), 15654-15657, 2017 | 114 | 2017 |
Numerical modeling of simulated blood flow in idealized composite arterial coronary grafts: Steady state simulations AK Politis, GP Stavropoulos, MN Christolis, FG Panagopoulos, ... Journal of Biomechanics 40 (5), 1125-1136, 2007 | 102 | 2007 |
Ion mobility–mass spectrometry of a rotary ATPase reveals ATP-induced reduction in conformational flexibility M Zhou, A Politis, RB Davies, I Liko, KJ Wu, AG Stewart, D Stock, ... Nature chemistry 6 (3), 208-215, 2014 | 94 | 2014 |
Ion mobility mass spectrometry of two tetrameric membrane protein complexes reveals compact structures and differences in stability and packing SC Wang, A Politis, N Di Bartolo, VN Bavro, SJ Tucker, PJ Booth, ... Journal of the American Chemical Society 132 (44), 15468-15470, 2010 | 92 | 2010 |
Structural lipids enable the formation of functional oligomers of the eukaryotic purine symporter UapA E Pyle, AC Kalli, S Amillis, Z Hall, AM Lau, AC Hanyaloglu, G Diallinas, ... Cell chemical biology 25 (7), 840-848. e4, 2018 | 88 | 2018 |
Deuteros 2.0: peptide-level significance testing of data from hydrogen deuterium exchange mass spectrometry AM Lau, J Claesen, K Hansen, A Politis Bioinformatics 37 (2), 270-272, 2021 | 85 | 2021 |
Numerical modelling of simulated blood flow in idealized composite arterial coronary grafts: Transient flow AK Politis, GP Stavropoulos, MN Christolis, PG Panagopoulos, ... Journal of Biomechanics 41 (1), 25-39, 2008 | 77 | 2008 |
Specific cardiolipin–SecY interactions are required for proton-motive force stimulation of protein secretion RA Corey, E Pyle, WJ Allen, DW Watkins, M Casiraghi, B Miroux, ... Proceedings of the National Academy of Sciences 115 (31), 7967-7972, 2018 | 76 | 2018 |
Native mass spectrometry goes more native: investigation of membrane protein complexes directly from SMALPs N Hellwig, O Peetz, Z Ahdash, I Tascón, PJ Booth, V Mikusevic, ... Chemical Communications 54 (97), 13702-13705, 2018 | 71 | 2018 |
Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry AMC Lau, Z Ahdash, C Martens, A Politis Bioinformatics 35 (17), 3171-3173, 2019 | 69 | 2019 |