| Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent. AJ Fosang, K Last, RA Maciewicz The Journal of clinical investigation 98 (10), 2292-2299, 1996 | 260 | 1996 |
| Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized DJ Hunter, L Gerstenfeld, G Bishop, AD Davis, ZD Mason, TA Einhorn, ... Arthritis research & therapy 11, 1-9, 2009 | 250 | 2009 |
| Nonspherical femoral head shape (pistol grip deformity), neck shaft angle, and risk of hip osteoarthritis: a case–control study M Doherty, P Courtney, S Doherty, W Jenkins, RA Maciewicz, K Muir, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2008 | 248 | 2008 |
| Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1 L Howard, KK Nelson, RA Maciewicz, CP Blobel Journal of Biological Chemistry 274 (44), 31693-31699, 1999 | 239 | 1999 |
| Treatment with soluble VEGF receptor reduces disease severity in murine collagen-induced arthritis J Miotla, R Maciewicz, J Kendrew, M Feldmann, E Paleolog Laboratory investigation 80 (8), 1195-1205, 2000 | 220 | 2000 |
| Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28 L HOWARD, RA MACIEWICZ, CP BLOBEL Biochemical Journal 348 (1), 21-27, 2000 | 207 | 2000 |
| The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance AM Valdes, E Evangelou, HJM Kerkhof, A Tamm, SA Doherty, K Kisand, ... Annals of the rheumatic diseases 70 (5), 873-875, 2011 | 203 | 2011 |
| A comparison of four cathepsins (B, L, N and S) with collagenolytic activity from rabbit spleen RA Maciewicz, DJ Etherington Biochemical Journal 256 (2), 433-440, 1988 | 200 | 1988 |
| Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis MC Castaño Betancourt, F Cailotto, HJ Kerkhof, FMF Cornelis, ... Proceedings of the National Academy of Sciences 109 (21), 8218-8223, 2012 | 196 | 2012 |
| Susceptibility of the cartilage collagens types II, IX and XI to degradation by the cysteine proteinases, cathepsins B and L RA Maciewicz, SF Wotton, DJ Etherington, VC Duance FEBS letters 269 (1), 189-193, 1990 | 195 | 1990 |
| A variant in MCF2L is associated with osteoarthritis AG Day-Williams, L Southam, K Panoutsopoulou, NW Rayner, T Esko, ... The American Journal of Human Genetics 89 (3), 446-450, 2011 | 179 | 2011 |
| Temporal relationship between serum adipokines, biomarkers of bone and cartilage turnover, and cartilage volume loss in a population with clinical knee osteoarthritis PA Berry, SW Jones, FM Cicuttini, AE Wluka, RA Maciewicz Arthritis & Rheumatism 63 (3), 700-707, 2011 | 173 | 2011 |
| Lifetime body mass index, other anthropometric measures of obesity and risk of knee or hip osteoarthritis in the GOAL case-control study KL Holliday, DF McWilliams, RA Maciewicz, KR Muir, W Zhang, M Doherty Osteoarthritis and Cartilage 19 (1), 37-43, 2011 | 165 | 2011 |
| Diurnal variation in the femoral articular cartilage of the knee in young adult humans JC Waterton, S Solloway, JE Foster, MC Keen, S Gandy, BJ Middleton, ... Magnetic Resonance in Medicine: An Official Journal of the International …, 2000 | 162 | 2000 |
| The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis AM Valdes, G De Wilde, SA Doherty, RJ Lories, FL Vaughn, LL Laslett, ... Annals of the rheumatic diseases 70 (9), 1556-1561, 2011 | 146 | 2011 |
| New α-substituted succinate-based hydroxamic acids as TNFα convertase inhibitors B Barlaam, TG Bird, C Lambert-van der Brempt, D Campbell, SJ Foster, ... Journal of medicinal chemistry 42 (23), 4890-4908, 1999 | 143 | 1999 |
| Mapping pathogenesis of arthritis through small animal models TL Vincent, RO Williams, R Maciewicz, A Silman, P Garside, ... Rheumatology 51 (11), 1931-1941, 2012 | 142 | 2012 |
| Immunodetection of cathepsins B and L present in and secreted from human pre‐malignant and malignant colorectal tumour cell lines RA Maciewicz, R John Wardale, DJ Etherington, C Paraskeva International journal of cancer 43 (3), 478-486, 1989 | 136 | 1989 |
| Integrin α5β1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells DV Bax, AJ Messent, J Tart, M Van Hoang, J Kott, RA Maciewicz, ... Journal of Biological Chemistry 279 (21), 22377-22386, 2004 | 135 | 2004 |
| Activation of cathepsin B, secreted by a colorectal cancer cell line requires low pH and is mediated by cathepsin D JWJ Van Der Stappen, AC Williams, RA Maciewicz, C Paraskeva International journal of cancer 67 (4), 547-554, 1996 | 131 | 1996 |
