Memantine for dementia R McShane, MJ Westby, E Roberts, N Minakaran, L Schneider, ... Cochrane database of systematic reviews, 2019 | 464 | 2019 |
Memantine and cholinesterase inhibitor combination therapy for Alzheimer's disease: a systematic review LE Farrimond, E Roberts, R McShane BMJ open 2 (3), e000917, 2012 | 143 | 2012 |
Impairment of mitochondrial calcium buffering links mutations in C9orf72 and TARDBP in iPS-derived motor neurons from patients with ALS/FTD R Dafinca, C Sathyaprakash, P Barbagallo, L Farrimond, N Ababneh, ... Stem Cell Reports, 2020 | 131 | 2020 |
Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor … D Gordon, R Dafinca, J Scaber, J Alegre-Abarrategui, L Farrimond, ... Neurobiology of disease 121, 148-162, 2019 | 80 | 2019 |
TARDBP pathogenic mutations increase cytoplasmic translocation of TDP-43 and cause reduction of endoplasmic reticulum Ca 2+ signaling in motor neurons R Mutihac, J Alegre-Abarrategui, D Gordon, L Farrimond, ... Neurobiology of disease 75, 64-77, 2015 | 76 | 2015 |
Multicentre appraisal of amyotrophic lateral sclerosis biofluid biomarkers shows primacy of blood neurofilament light chain AG Thompson, E Gray, N Verber, Y Bobeva, V Lombardi, SR Shepheard, ... Brain communications 4 (1), fcac029, 2022 | 68 | 2022 |
Human iPSC co-culture model to investigate the interaction between microglia and motor neurons BF Vahsen, E Gray, A Candalija, KML Cramb, J Scaber, R Dafinca, ... Scientific Reports 12 (1), 12606, 2022 | 26 | 2022 |
Initial Identification of a Blood-Based Chromosome Conformation Signature for Aiding in the Diagnosis of Amyotrophic Lateral Sclerosis M Salter, E Corfield, A Ramadass, F Grand, J Green, J Westra, CR Lim, ... EBioMedicine, 2018 | 26 | 2018 |
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9 BF Vahsen, S Nalluru, GR Morgan, L Farrimond, E Carroll, Y Xu, ... Nature Communications 14 (1), 5898, 2023 | 21 | 2023 |
A case of SOD1 deficiency: implications for clinical trials L Farrimond, K Talbot Brain 145 (3), 805-806, 2022 | 4 | 2022 |
Advantages of routine next generation sequencing over standard genetic testing in the ALS clinic J Scaber, AG Thompson, L Farrimond, E Feneberg, M Proudfoot, ... European Journal of Neurology, 2023 | 1 | 2023 |
BRAIN COMMUNICATIONS AIN COMMUNICATIONS AG Thompson, E Gray, N Verber, Y Bobeva, V Lombardi, SR Shepheard, ... | | 2022 |
Helen Easdale Dimsdale L Farrimond, K Talbot The Lancet Neurology 16 (3), 185, 2017 | | 2017 |
TARDBP pathogenic mutations increase cytoplasmic translocation of TDP-43 and cause reduction of endoplasmic reticulum Ca2+ signaling in motor neurons K Talbot, R Wade-Martins Neurobiology of Disease 75, 64-77, 2015 | | 2015 |
Cytoplasmic Redistribution of Mutant TDP-43 in a BAC Based Mouse Model of Amyotrophic Lateral Sclerosis (I11-1.007) K Talbot, D Gordon, R Mutihac, J Alegre-Abarrategui, L Farrimond, ... Neurology 82 (10 Supplement), I11-1.007-I11-1.007, 2014 | | 2014 |
Cytoplasmic Redistribution of Mutant TDP-43 in a BAC Based Mouse Model of Amyotrophic Lateral Sclerosis (P3. 012) K Talbot, D Gordon, R Mutihac, J Alegre-Abarrategui, L Farrimond, ... Neurology 82 (10 Supplement), P3. 012-P3. 012, 2014 | | 2014 |