Björn Titz
Björn Titz
Manager, Proteomics & Lipidomics Laboratory, PMI R&D
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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF (V600E)
PI Poulikakos, Y Persaud, M Janakiraman, X Kong, C Ng, G Moriceau, ...
Nature, 2011
Effects of MAPK and PI3K pathways on PD-L1 expression in melanoma
M Atefi, E Avramis, A Lassen, DJL Wong, L Robert, D Foulad, M Cerniglia, ...
Clinical cancer research 20 (13), 3446-3457, 2014
Evolutionarily conserved herpesviral protein interaction networks
E Fossum, CC Friedel, SV Rajagopala, B Titz, A Baiker, T Schmidt, ...
PLoS pathogens 5 (9), e1000570, 2009
MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells
D Ploper, VF Taelman, L Robert, BS Perez, B Titz, HW Chen, TG Graeber, ...
Proceedings of the National Academy of Sciences 112 (5), E420-E429, 2015
Phosphoproteome integration reveals patient-specific networks in prostate cancer
JM Drake, EO Paull, NA Graham, JK Lee, BA Smith, B Titz, T Stoyanova, ...
Cell 166 (4), 1041-1054, 2016
The protein network of bacterial motility
SV Rajagopala, B Titz, J Goll, JR Parrish, K Wohlbold, MT McKevitt, ...
Molecular systems biology 3 (1), 128, 2007
The binary protein interactome of Treponema pallidum–the syphilis spirochete
B Titz, SV Rajagopala, J Goll, R Häuser, MT McKevitt, T Palzkill, P Uetz
PloS one 3 (5), e2292, 2008
What do we learn from high-throughput protein interaction data?
B Titz, M Schlesner, P Uetz
Expert review of proteomics 1 (1), 111-121, 2004
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia
Z Chen, S Shojaee, M Buchner, H Geng, JW Lee, L Klemm, B Titz, ...
Nature 521 (7552), 357-361, 2015
Transcriptional activators in yeast
B Titz, S Thomas, SV Rajagopala, T Chiba, T Ito, P Uetz
Nucleic acids research 34 (3), 955-967, 2006
Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets
JM Drake, NA Graham, JK Lee, T Stoyanova, CM Faltermeier, S Sud, ...
Proceedings of the National Academy of Sciences 110 (49), E4762-E4769, 2013
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint
S Swaminathan, C Huang, H Geng, Z Chen, R Harvey, H Kang, C Ng, ...
Nature medicine 19 (8), 1014-1022, 2013
An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe−/− Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate …
B Phillips, E Veljkovic, S Boué, WK Schlage, G Vuillaume, F Martin, B Titz, ...
Toxicological Sciences 149 (2), 411-432, 2016
RsfA (YbeB) proteins are conserved ribosomal silencing factors
R Häuser, M Pech, J Kijek, H Yamamoto, B Titz, F Naeve, ...
PLoS genetics 8 (7), e1002815, 2012
A 7-month cigarette smoke inhalation study in C57BL/6 mice demonstrates reduced lung inflammation and emphysema following smoking cessation or aerosol exposure from a …
B Phillips, E Veljkovic, MJ Peck, A Buettner, A Elamin, E Guedj, ...
Food and Chemical Toxicology 80, 328-345, 2015
Matrix metalloproteinase 19 processes the laminin 5 gamma 2 chain and induces epithelial cell migration
T Sadowski, S Dietrich, F Koschinsky, A Ludwig, E Proksch, B Titz, ...
Cellular and Molecular Life Sciences CMLS 62 (7), 870-880, 2005
Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by …
B Phillips, B Titz, U Kogel, D Sharma, P Leroy, Y Xiang, G Vuillaume, ...
Food and Chemical Toxicology 109, 315-332, 2017
Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects
B Titz, A Sewer, T Schneider, A Elamin, F Martin, S Dijon, K Luettich, ...
Journal of proteomics 128, 306-320, 2015
Global phosphoproteomics reveals crosstalk between Bcr-Abl and negative feedback mechanisms controlling Src signaling
L Rubbi, B Titz, L Brown, E Galvan, E Komisopoulou, SS Chen, T Low, ...
Science signaling 4 (166), ra18-ra18, 2011
Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe−/− Mice—An …
B Titz, S Boué, B Phillips, M Talikka, T Vihervaara, T Schneider, C Nury, ...
Toxicological Sciences 149 (2), 441-457, 2016
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