Alina Isakova
Alina Isakova
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Systematic dissection of genomic features determining transcription factor binding and enhancer function
SR Grossman, X Zhang, L Wang, J Engreitz, A Melnikov, P Rogov, ...
Proceedings of the National Academy of Sciences 114 (7), E1291-E1300, 2017
Topology and dynamics of the zebrafish segmentation clock core circuit
C Schröter, S Ares, LG Morelli, A Isakova, K Hens, D Soroldoni, ...
PLoS biology 10 (7), e1001364, 2012
Integrative genomics identifies the corepressor SMRT as a gatekeeper of adipogenesis through the transcription factors C/EBPβ and KAISO
SK Raghav, SM Waszak, I Krier, C Gubelmann, A Isakova, TS Mikkelsen, ...
Molecular cell 46 (3), 335-350, 2012
Automated protein-DNA interaction screening of Drosophila regulatory elements
K Hens, JD Feuz, A Isakova, A Iagovitina, A Massouras, J Bryois, ...
Nature methods 8 (12), 1065-1070, 2011
SMiLE-seq identifies binding motifs of single and dimeric transcription factors
A Isakova, R Groux, M Imbeault, P Rainer, D Alpern, R Dainese, ...
Nature methods 14 (3), 316-322, 2017
Single-cell transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei
J Ren, A Isakova, D Friedmann, J Zeng, SM Grutzner, A Pun, GQ Zhao, ...
Elife 8, e49424, 2019
Single-cell transcriptomic atlas of the human endometrium during the menstrual cycle
W Wang, F Vilella, P Alama, I Moreno, M Mignardi, A Isakova, W Pan, ...
Nature Medicine 26 (10), 1644-1653, 2020
A yeast one‐hybrid and microfluidics‐based pipeline to map mammalian gene regulatory networks
C Gubelmann, SM Waszak, A Isakova, W Holcombe, K Hens, A Iagovitina, ...
Molecular systems biology 9 (1), 682, 2013
Quantification of cooperativity in heterodimer-DNA binding improves the accuracy of binding specificity models.
A Isakova, Y Berset, V Hatzimanikatis, D Bart
J Biol Chem., 2016
A mouse tissue atlas of small noncoding RNA
A Isakova, T Fehlmann, A Keller, SR Quake
Proceedings of the National Academy of Sciences 117 (41), 25634-25645, 2020
miRSwitch: detecting microRNA arm shift and switch events
F Kern, J Amand, I Senatorov, A Isakova, C Backes, E Meese, A Keller, ...
Nucleic acids research 48 (W1), W268-W274, 2020
Single cell profiling of total RNA using Smart-seq-total
A Isakova, N Neff, SR Quake
bioRxiv, 2020
Serotonin Neurons in the Dorsal and Medial Raphe Nuclei: from Single-Cell Transcriptomes to Whole-Brain Projections
J Ren, A Isakova, D Friedmann, J Zeng, S Grutzner, A Pun, GQ Zhao, ...
BioRxiv, 674697, 2019
SMiLE-seq: Selective Microfluidics-based Ligand Enrichment followed by sequencing
A Isakova, R Groux, G Ambrosini, P Bucher, B Deplancke
Deconvoluting complex correlates of COVID19 severity with local ancestry inference and viral phylodynamics: Results of a multiomic pandemic tracking strategy
VN Parikh, AG Ioannidis, D Jimenez-Morales, JE Gorzynski, HN De Jong, ...
medRxiv, 2021
Microfluidic Device and Method for Isolation of Nucleic Acid
A Isakova, B Deplancke
US Patent App. 15/518,264, 2019
SMiLE-seq: Selective Microfluidics-based Ligand Enrichment followed by sequencing
B Deplancke, A Isakova, R Groux, G Ambrosini, P Bucher
Dissecting the DNA binding principles of transcription factor monomers and heterodimers
A Isakova
EPFL, 2014
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