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Barrie Wilkinson
Barrie Wilkinson
Professor of Molecular Microbiology, John Innes Centre
Verified email at jic.ac.uk - Homepage
Title
Cited by
Cited by
Year
Antibiotics: past, present and future
MI Hutchings, AW Truman, B Wilkinson
Current opinion in microbiology 51, 72-80, 2019
18252019
Minimum information about a biosynthetic gene cluster
MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ...
Nature chemical biology 11 (9), 625-631, 2015
8512015
Drug discovery beyond the ‘rule-of-five’
MQ Zhang, B Wilkinson
Current opinion in biotechnology 18 (6), 478-488, 2007
4382007
Biosynthesis of erythromycin and rapamycin
J Staunton, B Wilkinson
Chemical reviews 97 (7), 2611-2630, 1997
3431997
Engineering broader specificity into an antibiotic-producing polyketide synthase
AFA Marsden, B Wilkinson, J Cortes, NJ Dunster, J Staunton, PF Leadlay
Science 279 (5348), 199-202, 1998
3311998
Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor
Z Hojati, C Milne, B Harvey, L Gordon, M Borg, F Flett, B Wilkinson, ...
Chemistry & biology 9 (11), 1175-1187, 2002
3222002
Mining and engineering natural-product biosynthetic pathways
B Wilkinson, J Micklefield
Nature chemical biology 3 (7), 379-386, 2007
2812007
Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tü4055: cluster analysis and assignment of functions
C Olano, B Wilkinson, C Sánchez, SJ Moss, R Sheridan, V Math, ...
Chemistry & biology 11 (1), 87-97, 2004
2042004
Loss of co-linearity by modular polyketide synthases: a mechanism for the evolution of chemical diversity
SJ Moss, CJ Martin, B Wilkinson
Natural product reports 21 (5), 575-593, 2004
1662004
Formicamycins, antibacterial polyketides produced by Streptomyces formicae isolated from African Tetraponera plant-ants
Z Qin, JT Munnoch, R Devine, NA Holmes, RF Seipke, KA Wilkinson, ...
Chemical Science 8 (4), 3218-3227, 2017
1592017
Active-site residue, domain and module swaps in modular polyketide synthases
F Del Vecchio, H Petkovic, SG Kendrew, L Low, B Wilkinson, R Lill, ...
Journal of Industrial Microbiology and Biotechnology 30 (8), 489-494, 2003
1502003
Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues
A Ranganathan, M Timoney, M Bycroft, J Cortés, IP Thomas, B Wilkinson, ...
Chemistry & biology 6 (10), 731-741, 1999
1501999
Tritiated Chiral Alkanes as Substrates for Soluble Methane Monooxygenase from Methylococcus capsulatus (Bath):  Probes for the Mechanism of Hydroxylation
AM Valentine, B Wilkinson, KE Liu, S Komar-Panicucci, ND Priestley, ...
Journal of the American Chemical Society 119 (8), 1818-1827, 1997
1501997
Mutasynthesis of rapamycin analogues through the manipulation of a gene governing starter unit biosynthesis
MA Gregory, H Petkovic, RE Lill, SJ Moss, B Wilkinson, S Gaisser, ...
Angewandte Chemie International Edition 44 (30), 4757-4760, 2005
1392005
Roles of rapH and rapG in Positive Regulation of Rapamycin Biosynthesis in Streptomyces hygroscopicus
E Kuščer, N Coates, I Challis, M Gregory, B Wilkinson, R Sheridan, ...
Journal of bacteriology 189 (13), 4756-4763, 2007
1292007
Engineering a polyketide with a longer chain by insertion of an extra module into the erythromycin-producing polyketide synthase
CJ Rowe, IU Böhm, IP Thomas, B Wilkinson, BAM Rudd, G Foster, ...
Chemistry & biology 8 (5), 475-485, 2001
1282001
Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate
JN Andexer, SG Kendrew, M Nur-e-Alam, O Lazos, TA Foster, ...
Proceedings of the National Academy of Sciences 108 (12), 4776-4781, 2011
1252011
A Concerted Mechanism for Ethane Hydroxylation by the Particulate Methane Monooxygenase from Methylococcus capsulatus (Bath)
B Wilkinson, M Zhu, ND Priestley, HHT Nguyen, H Morimoto, PG Williams, ...
Journal of the American Chemical Society 118 (4), 921-922, 1996
1201996
Engineered urdamycin glycosyltransferases are broadened and altered in substrate specificity
D Hoffmeister, B Wilkinson, G Foster, PJ Sidebottom, K Ichinose, ...
Chemistry & biology 9 (3), 287-295, 2002
1192002
Combinatorial biosynthesis of polyketides and nonribosomal peptides
J Staunton, B Wilkinson
Current opinion in chemical biology 5 (2), 159-164, 2001
1132001
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