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Sergiy Velychko
Sergiy Velychko
Harvard Medical School
Verified email at hms.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors
M Ehrlich, S Mozafari, M Glatza, L Starost, S Velychko, AL Hallmann, ...
Proceedings of the National Academy of Sciences 114 (11), E2243-E2252, 2017
2392017
Excluding Oct4 from Yamanaka cocktail unleashes the developmental potential of iPSCs
S Velychko, K Adachi, KP Kim, Y Hou, CM MacCarthy, G Wu, HR Schöler
Cell Stem Cell 25 (6), 737-753. e4, 2019
1152019
Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2
V Malik, LV Glaser, D Zimmer, S Velychko, M Weng, M Holzner, M Arend, ...
Nature communications 10 (1), 3477, 2019
672019
Changing POU dimerization preferences converts Oct6 into a pluripotency inducer
S Jerabek, CKL Ng, G Wu, MJ Arauzo‐Bravo, KP Kim, D Esch, V Malik, ...
EMBO reports 18 (2), 319-333, 2017
452017
R-loops coordinate with SOX2 in regulating reprogramming to pluripotency
Y Li, Y Song, W Xu, Q Li, X Wang, K Li, J Wang, Z Liu, S Velychko, R Ye, ...
Science Advances 6 (24), eaba0777, 2020
442020
Reprogramming competence of OCT factors is determined by transactivation domains
KP Kim, Y Wu, J Yoon, K Adachi, G Wu, S Velychko, CM MacCarthy, ...
Science advances 6 (36), eaaz7364, 2020
332020
One-step reprogramming of human fibroblasts into oligodendrocyte-like cells by SOX10, OLIG2, and NKX6. 2
K Chanoumidou, B Hernández-Rodríguez, F Windener, C Thomas, ...
Stem Cell Reports 16 (4), 771-783, 2021
272021
Functional restoration of gp91phox-oxidase activity by BAC transgenesis and gene targeting in X-linked chronic granulomatous disease iPSCs
M Laugsch, M Rostovskaya, S Velychko, C Richter, A Zimmer, B Klink, ...
Molecular Therapy 24 (4), 812-822, 2016
252016
Fusion of reprogramming factors alters the trajectory of somatic lineage conversion
S Velychko, K Kang, SM Kim, TH Kwak, KP Kim, C Park, K Hong, ...
Cell Reports 27 (1), 30-39. e4, 2019
232019
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
L Xiong, EA Tolen, J Choi, S Velychko, L Caizzi, T Velychko, K Adachi, ...
Elife 11, e71533, 2022
202022
Directed evolution of an enhanced POU reprogramming factor for cell fate engineering
DS Tan, Y Chen, Y Gao, A Bednarz, Y Wei, V Malik, DHH Ho, M Weng, ...
Molecular biology and evolution 38 (7), 2854-2868, 2021
132021
Enhanced OCT4 transcriptional activity substitutes for exogenous SOX2 in cellular reprogramming
AG Marthaler, K Adachi, U Tiemann, G Wu, D Sabour, S Velychko, ...
Scientific Reports 6 (1), 19415, 2016
82016
Highly cooperative chimeric super-SOX induces naive pluripotency across species
CM MacCarthy, G Wu, V Malik, Y Menuchin-Lasowski, T Velychko, ...
Cell Stem Cell 31 (1), 127-147. e9, 2024
72024
Efficient human germ cell specification from stem cells via combinatorial expression of transcription factors
C Kramme, MP Smela, B Wolf, PR Fortuna, G Brixi, K Palepu, E Dong, ...
32022
Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids
I Rosety, A Zagare, C Saraiva, S Nickels, P Antony, C Almeida, E Glaab, ...
npj Parkinson's Disease 9 (1), 166, 2023
22023
Enhancing Sox/Oct cooperativity induces higher-grade developmental reset
CM MacCarthy, V Malik, G Wu, T Velychko, G Keshet, R Jauch, ...
bioRxiv, 2022.09. 23.509242, 2022
22022
Sendai virus persistence questions the transient naive reprogramming method for iPSC generation
A De Los Angeles, CB Hug, VN Gladyshev, GM Church, S Velychko
bioRxiv, 2024
12024
Redefining SOX2 as a bifunctional mediator of transcription and adjusted translation control
N Mittal, M Ataman, H Wang, S Candido, J Lötscher, S Velychko, ...
Cancer Research 84 (6_Supplement), 255-255, 2024
2024
Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in mouse early embryos
Y Hou, Z Nie, Q Jiang, S Velychko, S Heising, I Bedzhov, G Wu, K Adachi, ...
bioRxiv, 2023.10. 18.562912, 2023
2023
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