| Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms MR Rondon, PR August, AD Bettermann, SF Brady, TH Grossman, ... Applied and environmental microbiology 66 (6), 2541-2547, 2000 | 1737 | 2000 |
| Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ... Nature medicine 24 (3), 313-325, 2018 | 536 | 2018 |
| Recombinant environmental libraries provide access to microbial diversity for drug discovery from natural products S Courtois, CM Cappellano, M Ball, FX Francou, P Normand, G Helynck, ... Applied and environmental microbiology 69 (1), 49-55, 2003 | 525 | 2003 |
| Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699 PR August, L Tang, YJ Yoon, S Ning, R Müller, TW Yu, M Taylor, ... Chemistry & biology 5 (2), 69-79, 1998 | 432 | 1998 |
| Expression and isolation of antimicrobial small molecules from soil DNA libraries IA MacNeil, CL Tiong, C Minor, PR August, TH Grossman, KA Loiacono, ... Journal of molecular microbiology and biotechnology 3 (2), 301-308, 2001 | 333 | 2001 |
| Sequence analysis and functional characterization of the violacein biosynthetic pathway from Chromobacterium violaceum PR August, TH Grossman, C Minor, MP Draper, IA MacNeil, ... Journal of molecular microbiology and biotechnology 2 (4), 513-519, 2000 | 198 | 2000 |
| In vitro myelin formation using embryonic stem cells BE Kerman, HJ Kim, K Padmanabhan, A Mei, S Georges, MS Joens, ... Development 142 (12), 2213-2225, 2015 | 104 | 2015 |
| Tapping into microbial diversity for natural products drug discovery TH Grossman ASM News 66 (7), 2000 | 78 | 2000 |
| A human in vitro model of Duchenne muscular dystrophy muscle formation and contractility AP Nesmith, MA Wagner, FS Pasqualini, BB O’Connor, MJ Pincus, ... Journal of Cell Biology 215 (1), 47-56, 2016 | 77 | 2016 |
| Cloning and analysis of a locus (mcr) involved in mitomycin C resistance in Streptomyces lavendulae PR August, MC Flickinger, DH Sherman Journal of bacteriology 176 (14), 4448-4454, 1994 | 76 | 1994 |
| Characterization of a mitomycin-binding drug resistance mechanism from the producing organism, Streptomyces lavendulae PJ Sheldon, DA Johnson, PR August, HW Liu, DH Sherman Journal of bacteriology 179 (5), 1796-1804, 1997 | 63 | 1997 |
| Developing defined substrates for stem cell culture and differentiation L Hagbard, K Cameron, P August, C Penton, M Parmar, DC Hay, T Kallur Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 60 | 2018 |
| Identification of novel tumor-associated cell surface sialoglycoproteins in human glioblastoma tumors using quantitative proteomics F Autelitano, D Loyaux, S Roudieres, C Deon, F Guette, P Fabre, Q Ping, ... PloS one 9 (10), e110316, 2014 | 47 | 2014 |
| Microbial resistance to mitomycins involves a redox relay mechanism DA Johnson, PR August, C Shackleton, H Liu, DH Sherman Journal of the American Chemical Society 119 (10), 2576-2577, 1997 | 41 | 1997 |
| Laminin 521 maintains differentiation potential of mouse and human satellite cell-derived myoblasts during long-term culture expansion CM Penton, V Badarinarayana, J Prisco, E Powers, M Pincus, RE Allen, ... Skeletal muscle 6, 1-16, 2016 | 37 | 2016 |
| A functional screen in human cells identifies UBF2 as an RNA polymerase II transcription factor that enhances the β-catenin signaling pathway DA Grueneberg, L Pablo, KQ Hu, P August, Z Weng, J Papkoff Molecular and cellular biology, 2003 | 37 | 2003 |
| Compound screening platform using human induced pluripotent stem cells to identify small molecules that promote chondrogenesis SL Yang, E Harnish, T Leeuw, U Dietz, E Batchelder, PS Wright, ... Protein & cell 3, 934-942, 2012 | 32 | 2012 |
| Efficient cloning of full-length cDNAs based on cDNA size fractionation MP Draper, PR August, T Connolly, B Packard, KM Call Genomics 79 (4), 603-607, 2002 | 23 | 2002 |
| Inducible synthesis of the mitomycin C resistance gene product (MCRA) from Streptomyces lavendulae PR August, JA Rahn, MC Flickinger, DH Sherman Gene 175 (1-2), 261-267, 1996 | 19 | 1996 |
| High-content phenotypic screening and triaging strategy to identify small molecules driving oligodendrocyte progenitor cell differentiation JV Peppard, CA Rugg, MA Smicker, E Powers, E Harnish, J Prisco, ... Journal of biomolecular screening 20 (3), 382-390, 2015 | 17 | 2015 |
