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Jaclyn Hechtman
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Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
A Zehir, R Benayed, RH Shah, A Syed, S Middha, HR Kim, P Srinivasan, ...
Nature medicine 23 (6), 703-713, 2017
28922017
Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children
A Drilon, TW Laetsch, S Kummar, SG DuBois, UN Lassen, GD Demetri, ...
New England Journal of Medicine 378 (8), 731-739, 2018
24492018
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): a hybridization capture-based next-generation sequencing clinical assay for …
DT Cheng, TN Mitchell, A Zehir, RH Shah, R Benayed, A Syed, ...
The Journal of molecular diagnostics 17 (3), 251-264, 2015
17112015
Clinical sequencing defines the genomic landscape of metastatic colorectal cancer
R Yaeger, WK Chatila, MD Lipsyc, JF Hechtman, A Cercek, ...
Cancer cell 33 (1), 125-136. e3, 2018
6712018
Analysis of the prevalence of microsatellite instability in prostate cancer and response to immune checkpoint blockade
W Abida, ML Cheng, J Armenia, S Middha, KA Autio, HA Vargas, ...
JAMA oncology 5 (4), 471-478, 2019
5272019
Microsatellite instability is associated with the presence of Lynch syndrome pan-cancer
A Latham, P Srinivasan, Y Kemel, J Shia, C Bandlamudi, D Mandelker, ...
Journal of clinical oncology 37 (4), 286, 2019
4852019
Prospective genotyping of hepatocellular carcinoma: clinical implications of next-generation sequencing for matching patients to targeted and immune therapies
JJ Harding, S Nandakumar, J Armenia, DN Khalil, M Albano, M Ly, J Shia, ...
Clinical Cancer Research 25 (7), 2116-2126, 2019
4582019
NTRK fusion detection across multiple assays and 33,997 cases: diagnostic implications and pitfalls
JP Solomon, I Linkov, A Rosado, K Mullaney, EY Rosen, D Frosina, ...
Modern Pathology 33 (1), 38-46, 2020
4492020
Genetic diversity of tumors with mismatch repair deficiency influences anti–PD-1 immunotherapy response
R Mandal, RM Samstein, KW Lee, JJ Havel, H Wang, C Krishna, ...
Science 364 (6439), 485-491, 2019
4342019
Pan-Trk immunohistochemistry is an efficient and reliable screen for the detection of NTRK fusions
JF Hechtman, R Benayed, DM Hyman, A Drilon, A Zehir, D Frosina, ...
The American journal of surgical pathology 41 (11), 1547-1551, 2017
4182017
Comprehensive molecular profiling of intrahepatic and extrahepatic cholangiocarcinomas: potential targets for intervention
MA Lowery, R Ptashkin, E Jordan, MF Berger, A Zehir, M Capanu, ...
Clinical Cancer Research 24 (17), 4154-4161, 2018
4102018
A next-generation TRK kinase inhibitor overcomes acquired resistance to prior TRK kinase inhibition in patients with TRK fusion–positive solid tumors
A Drilon, R Nagasubramanian, JF Blake, N Ku, BB Tuch, K Ebata, S Smith, ...
Cancer discovery 7 (9), 963-972, 2017
3782017
ESMO recommendations on the standard methods to detect NTRK fusions in daily practice and clinical research
C Marchiò, M Scaltriti, M Ladanyi, AJ Iafrate, F Bibeau, M Dietel, ...
Annals of Oncology 30 (9), 1417-1427, 2019
3472019
Genetic predictors of response to systemic therapy in esophagogastric cancer
YY Janjigian, F Sanchez-Vega, P Jonsson, WK Chatila, JF Hechtman, ...
Cancer discovery 8 (1), 49-58, 2018
3082018
What hides behind the MASC: clinical response and acquired resistance to entrectinib after ETV6-NTRK3 identification in a mammary analogue secretory carcinoma (MASC)
A Drilon, G Li, S Dogan, M Gounder, R Shen, M Arcila, L Wang, ...
Annals of Oncology 27 (5), 920-926, 2016
3072016
Reliable pan-cancer microsatellite instability assessment by using targeted next-generation sequencing data
S Middha, L Zhang, K Nafa, G Jayakumaran, D Wong, HR Kim, ...
JCO precision oncology 1, 1-17, 2017
3052017
First-line pembrolizumab and trastuzumab in HER2-positive oesophageal, gastric, or gastro-oesophageal junction cancer: an open-label, single-arm, phase 2 trial
YY Janjigian, SB Maron, WK Chatila, B Millang, SS Chavan, C Alterman, ...
The Lancet Oncology 21 (6), 821-831, 2020
2932020
ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper
A Dasari, VK Morris, CJ Allegra, C Atreya, AB Benson III, P Boland, ...
Nature reviews Clinical oncology 17 (12), 757-770, 2020
2612020
Reliable detection of mismatch repair deficiency in colorectal cancers using mutational load in next-generation sequencing panels
ZK Stadler, F Battaglin, S Middha, JF Hechtman, C Tran, A Cercek, ...
Journal of Clinical Oncology 34 (18), 2141, 2016
2412016
Identifying patients with NTRK fusion cancer
JP Solomon, R Benayed, JF Hechtman, M Ladanyi
Annals of Oncology 30, viii16-viii22, 2019
2342019
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