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Sakari Vanharanta
Sakari Vanharanta
Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki
Verified email at helsinki.fi
Title
Cited by
Cited by
Year
A CXCL1 paracrine network links cancer chemoresistance and metastasis
S Acharyya, T Oskarsson, S Vanharanta, S Malladi, J Kim, PG Morris, ...
Cell 150 (1), 165-178, 2012
11212012
Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
T Oskarsson, S Acharyya, XHF Zhang, S Vanharanta, SF Tavazoie, ...
Nature medicine 17 (7), 867-874, 2011
9572011
Origins of metastatic traits
S Vanharanta, J Massagué
Cancer cell 24 (4), 410-421, 2013
6122013
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling
S Tuupanen, M Turunen, R Lehtonen, O Hallikas, S Vanharanta, T Kivioja, ...
Nature genetics 41 (8), 885-890, 2009
5972009
Therapy-induced tumour secretomes promote resistance and tumour progression
AC Obenauf, Y Zou, AL Ji, S Vanharanta, W Shu, H Shi, X Kong, ...
Nature 520 (7547), 368-372, 2015
4852015
Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma
S Vanharanta, M Buchta, SR McWhinney, SK Virta, M Peçzkowska, ...
The American Journal of Human Genetics 74 (1), 153-159, 2004
4732004
Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer
S Vanharanta, W Shu, F Brenet, AA Hakimi, A Heguy, A Viale, VE Reuter, ...
Nature medicine 19 (1), 50-56, 2013
2272013
Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype
TV Petrova, A Nykänen, C Norrmén, KI Ivanov, LC Andersson, C Haglund, ...
Cancer cell 13 (5), 407-419, 2008
2162008
Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors
R Lehtonen, M Kiuru, S Vanharanta, J Sjöberg, LM Aaltonen, K Aittomäki, ...
The American journal of pathology 164 (1), 17-22, 2004
2062004
Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis
P Laiho, A Kokko, S Vanharanta, R Salovaara, H Sammalkorpi, ...
Oncogene 26 (2), 312-320, 2007
1872007
Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer
S Vanharanta, CB Marney, W Shu, M Valiente, Y Zou, A Mele, RB Darnell, ...
Elife 3, e02734, 2014
1572014
Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma
L Haas, A Elewaut, CL Gerard, C Umkehrer, L Leiendecker, M Pedersen, ...
Nature cancer 2 (7), 693-708, 2021
1232021
Allelic Imbalance at rs6983267 Suggests Selection of the Risk Allele in Somatic Colorectal Tumor Evolution
S Tuupanen, I Niittymaki, K Nousiainen, S Vanharanta, JP Mecklin, ...
Cancer research 68 (1), 14-17, 2008
852008
Distinct expression profile in fumarate-hydratase-deficient uterine fibroids
S Vanharanta, PJ Pollard, HJ Lehtonen, P Laiho, J Sjöberg, A Leminen, ...
Human molecular genetics 15 (1), 97-103, 2006
792006
Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis
H Ashrafian, L O'Flaherty, J Adam, V Steeples, YL Chung, P East, ...
Cancer research 70 (22), 9153-9165, 2010
772010
Metabolic profiling reveals a dependency of human metastatic breast cancer on mitochondrial serine and one-carbon unit metabolism
AM Li, GS Ducker, Y Li, JA Seoane, Y Xiao, S Melemenidis, Y Zhou, L Liu, ...
Molecular Cancer Research 18 (4), 599-611, 2022
692022
A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma
SE Syafruddin, P Rodrigues, E Vojtasova, SA Patel, MN Zaini, J Burge, ...
Nature communications 10 (1), 1152, 2019
692019
Metastatic competence can emerge with selection of preexisting oncogenic alleles without a need of new mutations
LS Jacob, S Vanharanta, AC Obenauf, M Pirun, A Viale, ND Socci, ...
Cancer research 75 (18), 3713-3719, 2015
642015
Epigenetic determinants of metastasis
SA Patel, S Vanharanta
Molecular oncology 11 (1), 79-96, 2017
632017
Field cancerization: something new under the sun
S Vanharanta, J Massagué
Cell 149 (6), 1179-1181, 2012
492012
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