| Vitamin B6 salvage enzymes: mechanism, structure and regulation ML Di Salvo, R Contestabile, MK Safo Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1814 (11), 1597-1608, 2011 | 273 | 2011 |
| Pyridoxal 5'-phosphate enzymes as targets for therapeutic agents A Amadasi, M Bertoldi, R Contestabile, S Bettati, B Cellini, ... Current medicinal chemistry 14 (12), 1291-1324, 2007 | 226 | 2007 |
| Crystal structure of glutamate-1-semialdehyde aminomutase: An α2-dimeric vitamin B6-dependent enzyme with asymmetry in structure and active site reactivity M Hennig, B Grimm, R Contestabile, RA John, JN Jansonius Proceedings of the National Academy of Sciences 94 (10), 4866-4871, 1997 | 165 | 1997 |
| Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis G Mkrtchyan, V Aleshin, Y Parkhomenko, T Kaehne, M Luigi Di Salvo, ... Scientific reports 5 (1), 12583, 2015 | 137 | 2015 |
| SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation A Paone, M Marani, A Fiascarelli, S Rinaldo, G Giardina, R Contestabile, ... Cell death & disease 5 (11), e1525-e1525, 2014 | 119 | 2014 |
| Biomedical aspects of pyridoxal 5′-phosphate availability ML di Salvo, MK Safo, R Contestabile Front Biosci (Elite Ed) 4, 897-913, 2012 | 119 | 2012 |
| l‐Threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase: A subgroup of strictly related enzymes specialized for different functions R Contestabile, A Paiardini, S Pascarella, ML di Salvo, S D'Aguanno, ... European Journal of Biochemistry 268 (24), 6508-6525, 2001 | 113 | 2001 |
| How pyridoxal 5′‐phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state G Giardina, P Brunotti, A Fiascarelli, A Cicalini, MGS Costa, AM Buckle, ... The FEBS journal 282 (7), 1225-1241, 2015 | 92 | 2015 |
| Mutation of tyrosine 332 to phenylalanine converts dopa decarboxylase into a decarboxylation-dependent oxidative deaminase M Bertoldi, M Gonsalvi, R Contestabile, CB Voltattorni Journal of Biological Chemistry 277 (39), 36357-36362, 2002 | 74 | 2002 |
| Glycine consumption and mitochondrial serine hydroxymethyltransferase in cancer cells: the heme connection ML di Salvo, R Contestabile, A Paiardini, B Maras Medical hypotheses 80 (5), 633-636, 2013 | 73 | 2013 |
| Serine hydroxymethyltransferase: a model enzyme for mechanistic, structural, and evolutionary studies R Florio, ML di Salvo, M Vivoli, R Contestabile Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1814 (11), 1489-1496, 2011 | 72 | 2011 |
| In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed F Daidone, R Florio, S Rinaldo, R Contestabile, ML di Salvo, F Cutruzzolà, ... European journal of medicinal chemistry 46 (5), 1616-1621, 2011 | 67 | 2011 |
| Coupling bioorthogonal chemistries with artificial metabolism: intracellular biosynthesis of azidohomoalanine and its incorporation into recombinant proteins Y Ma, H Biava, R Contestabile, N Budisa, ML Di Salvo Molecules 19 (1), 1004-1022, 2014 | 66 | 2014 |
| Pyridoxal 5′-Phosphate Is a Slow Tight Binding Inhibitor of E. coli Pyridoxal Kinase MS Ghatge, R Contestabile, ML di Salvo, JV Desai, AK Gandhi, ... Public Library of Science 7 (7), e41680, 2012 | 66 | 2012 |
| On the catalytic mechanism and stereospecificity of Escherichia coli l‐threonine aldolase ML di Salvo, SG Remesh, M Vivoli, MS Ghatge, A Paiardini, S D'Aguanno, ... The FEBS journal 281 (1), 129-145, 2014 | 65 | 2014 |
| Molecular basis of reduced pyridoxine 5′-phosphate oxidase catalytic activity in neonatal epileptic encephalopathy disorder FN Musayev, ML Di Salvo, MA Saavedra, R Contestabile, MS Ghatge, ... Journal of biological chemistry 284 (45), 30949-30956, 2009 | 61 | 2009 |
| Function of the active-site lysine in Escherichia coli serine hydroxymethyltransferase. D Schirch, S Delle Fratte, S Iurescia, S Angelaccio, R Contestabile, ... Journal of Biological Chemistry 268 (31), 23132-23138, 1993 | 60 | 1993 |
| A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells M Marani, A Paone, A Fiascarelli, A Macone, M Gargano, S Rinaldo, ... Oncotarget 7 (4), 4570, 2016 | 57 | 2016 |
| Alanine racemase from Tolypocladium inflatum: a key PLP-dependent enzyme in cyclosporin biosynthesis and a model of catalytic promiscuity ML di Salvo, R Florio, A Paiardini, M Vivoli, S D’Aguanno, R Contestabile Archives of Biochemistry and Biophysics 529 (2), 55-65, 2013 | 43 | 2013 |
| Role of a Conserved Active Site Cation−π Interaction in Escherichia coli Serine Hydroxymethyltransferase M Vivoli, F Angelucci, A Ilari, V Morea, S Angelaccio, ML di Salvo, ... Biochemistry 48 (50), 12034-12046, 2009 | 43 | 2009 |
