| Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1) X Yang, H Jin, X Cai, S Li, Y Shen Proceedings of the National Academy of Sciences 109 (15), 5657-5662, 2012 | 272 | 2012 |
| The Orai1 Store-Operated Calcium Channel Functions as a Hexamer*♦ X Cai, Y Zhou, RM Nwokonko, NA Loktionova, X Wang, P Xin, M Trebak, ... Journal of Biological Chemistry 291 (50), 25764-25775, 2016 | 129 | 2016 |
| The STIM1-binding site nexus remotely controls Orai1 channel gating Y Zhou, X Cai, NA Loktionova, X Wang, RM Nwokonko, X Wang, Y Wang, ... Nature communications 7 (1), 13725, 2016 | 102 | 2016 |
| STIM1 dimers undergo unimolecular coupling to activate Orai1 channels Y Zhou, X Wang, X Wang, NA Loktionova, X Cai, RM Nwokonko, E Vrana, ... Nature communications 6 (1), 8395, 2015 | 86 | 2015 |
| The STIM-Orai coupling interface and gating of the Orai1 channel Y Zhou, X Cai, RM Nwokonko, NA Loktionova, Y Wang, DL Gill Cell calcium 63, 8-13, 2017 | 84 | 2017 |
| Cross-linking of Orai1 channels by STIM proteins Y Zhou, RM Nwokonko, X Cai, NA Loktionova, R Abdulqadir, P Xin, ... Proceedings of the National Academy of Sciences 115 (15), E3398-E3407, 2018 | 80 | 2018 |
| Potent functional uncoupling between STIM1 and Orai1 by dimeric 2-aminodiphenyl borinate analogs E Hendron, X Wang, Y Zhou, X Cai, JI Goto, K Mikoshiba, Y Baba, ... Cell calcium 56 (6), 482-492, 2014 | 43 | 2014 |
| The STIM-Orai Pathway: Conformational Coupling Between STIM and Orai in the Activation of Store-Operated Ca2+ Entry RM Nwokonko, X Cai, NA Loktionova, Y Wang, Y Zhou, DL Gill Store-Operated Ca²⁺ Entry (SOCE) Pathways: Emerging Signaling Concepts in …, 2017 | 38 | 2017 |
| The δA isoform of calmodulin kinase II mediates pathological cardiac hypertrophy by interfering with the HDAC4-MEF2 signaling pathway C Li, X Cai, H Sun, T Bai, X Zheng, XW Zhou, X Chen, DL Gill, J Li, ... Biochemical and biophysical research communications 409 (1), 125-130, 2011 | 38 | 2011 |
| CpG-ODN attenuates pathological cardiac hypertrophy and heart failure by activation of PI3Kα-Akt signaling L Yang, X Cai, J Liu, Z Jia, J Jiao, J Zhang, C Li, J Li, XD Tang PloS one 8 (4), e62373, 2013 | 31 | 2013 |
| Protein kinase D3 is a pivotal activator of pathological cardiac hypertrophy by selectively increasing the expression of hypertrophic transcription factors C Li, J Li, X Cai, H Sun, J Jiao, T Bai, XW Zhou, X Chen, DL Gill, XD Tang Journal of Biological Chemistry 286 (47), 40782-40791, 2011 | 31 | 2011 |
| Pore properties of Orai1 calcium channel dimers and their activation by the STIM1 ER calcium sensor X Cai, RM Nwokonko, NA Loktionova, R Abdulqadir, JH Baraniak, ... Journal of Biological Chemistry 293 (33), 12962-12974, 2018 | 28 | 2018 |
| Structure of Neisseria meningitidis lipoprotein GNA1162 X Cai, J Lu, Z Wu, C Yang, H Xu, Z Lin, Y Shen Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 8 | 2013 |
| STIM Proteins Cluster Orai1 Channels and Modulate Receptor-Mediated Calcium Signals RM Nwokonko, Y Zhou, X Cai, N Loktionova, M Trebak, DL Gill Biophysical Journal 114 (3), 285a, 2018 | 2 | 2018 |
| Orai1 concatemers reveal a hexameric Orai1 channel assembly X Cai, Y Zhou, X Wang, N Loktionova, R Nwokonko, M Trebak, D Gill Biophysical Journal 110 (3), 264a-265a, 2016 | 1 | 2016 |
| Ion Conductance of Orai1 Channel Selectivity-Filter Heterodimers X Cai, Y Zhou, RM Nwokonko, NA Loktionova, DL Gill Biophysical Journal 114 (3), 132a, 2018 | | 2018 |
| STIM1-Induced Clustering of Orai1 Channels R Nwokonko, Y Zhou, X Cai, N Loktionova, X Wang, D Gill Biophysical Journal 110 (3), 265a, 2016 | | 2016 |
| A C-Terminal Switch Gates the Orai1 Channel Y Zhou, X Cai, NA Loktionova, X Wang, RM Nwokonko, M Trebak, DL Gill Biophysical Journal 110 (3), 359a-360a, 2016 | | 2016 |
| Functional Orai1 Dimers Assemble to Form Hexameric Channels X Cai, Y Zhou, X Wang, RM Nwokonko, NA Loktionova, DL Gill 第十一届全国钙信号和细胞功能研讨会摘要集, 2016 | | 2016 |
| Attenuation of Neointima Hyperplasia Without Thrombosis By a Small Molecule Inhibitor of the Store-Operated Channels T Wang, L Yang, J Li, Y Yu, X Cai, XL Zheng, DL Gill, XD Tang LABORATORY INVESTIGATION 95, 80A-80A, 2015 | | 2015 |
