| Classics in chemical neuroscience: memantine S Alam, KS Lingenfelter, AM Bender, CW Lindsley ACS Chemical Neuroscience 8 (9), 1823-1829, 2017 | 72 | 2017 |
| Classics in chemical neuroscience: xanomeline AM Bender, CK Jones, CW Lindsley ACS chemical neuroscience 8 (3), 435-443, 2017 | 60 | 2017 |
| Opioid peptidomimetics: leads for the design of bioavailable mixed efficacy μ opioid receptor (MOR) agonist/δ opioid receptor (DOR) antagonist ligands HI Mosberg, L Yeomans, AA Harland, AM Bender, K Sobczyk-Kojiro, ... Journal of medicinal chemistry 56 (5), 2139-2149, 2013 | 53 | 2013 |
| Discovery, characterization, and effects on renal fluid and electrolyte excretion of the Kir4. 1 potassium channel pore blocker, VU0134992 SV Kharade, H Kurata, AM Bender, AL Blobaum, EE Figueroa, A Duran, ... Molecular pharmacology 94 (2), 926-937, 2018 | 50 | 2018 |
| Effects of N-Substitutions on the Tetrahydroquinoline (THQ) Core of Mixed-Efficacy μ-Opioid Receptor (MOR)/δ-Opioid Receptor (DOR) Ligands AA Harland, AM Bender, NW Griggs, C Gao, JP Anand, ID Pogozheva, ... Journal of Medicinal Chemistry 59 (10), 4985-4998, 2016 | 36 | 2016 |
| Asymmetric synthesis and in vitro and in vivo activity of tetrahydroquinolines featuring a diverse set of polar substitutions at the 6 position as mixed-efficacy μ opioid … AM Bender, NW Griggs, JP Anand, JR Traynor, EM Jutkiewicz, ... ACS chemical neuroscience 6 (8), 1428-1435, 2015 | 32 | 2015 |
| Preparation of Unsymmetrical 1, 2, 4, 5-Tetrazines via a Mild Suzuki Cross-Coupling Reaction AM Bender, TC Chopko, TM Bridges, CW Lindsley Organic letters 19 (20), 5693-5696, 2017 | 31 | 2017 |
| Synthesis and evaluation of 4-substituted piperidines and piperazines as balanced affinity μ opioid receptor (MOR) agonist/δ opioid receptor (DOR) antagonist ligands AM Bender, MJ Clark, MP Agius, JR Traynor, HI Mosberg Bioorganic & medicinal chemistry letters 24 (2), 548-551, 2014 | 30 | 2014 |
| The Muscarinic Acetylcholine Receptor M5: Therapeutic Implications and Allosteric Modulation AM Bender, AT Garrison, CW Lindsley ACS chemical neuroscience 10 (3), 1025-1034, 2018 | 25 | 2018 |
| Rapid Synthesis of Boc-2′,6′-dimethyl-l-tyrosine and Derivatives and Incorporation into Opioid Peptidomimetics AM Bender, NW Griggs, C Gao, TJ Trask, JR Traynor, HI Mosberg ACS Medicinal Chemistry Letters 6 (12), 1199-1203, 2015 | 25 | 2015 |
| DARK classics in chemical neuroscience: carfentanil AE Ringuette, M Spock, CW Lindsley, AM Bender ACS Chemical Neuroscience 11 (23), 3955-3967, 2020 | 20 | 2020 |
| Discovery of the First Selective M4 Muscarinic Acetylcholine Receptor Antagonists with in Vivo Antiparkinsonian and Antidystonic Efficacy MS Moehle, AM Bender, JW Dickerson, DJ Foster, A Qi, HP Cho, ... ACS Pharmacology & Translational Science 4 (4), 1306-1321, 2021 | 17 | 2021 |
| Discovery and optimization of 3-(4-aryl/heteroarylsulfonyl) piperazin-1-yl)-6-(piperidin-1-yl) pyridazines as novel, CNS penetrant pan-muscarinic antagonists AM Bender, RL Weiner, VB Luscombe, S Ajmera, HP Cho, S Chang, ... Bioorganic & medicinal chemistry letters 27 (15), 3576-3581, 2017 | 13 | 2017 |
| Biased M1 receptor–positive allosteric modulators reveal role of phospholipase D in M1-dependent rodent cortical plasticity SP Moran, Z Xiang, CA Doyle, J Maksymetz, X Lv, S Faltin, NM Fisher, ... Science signaling 12 (610), eaax2057, 2019 | 12 | 2019 |
| Dual pharmacophores explored via structure–activity relationship (SAR) matrix: insights into potent, bifunctional opioid ligand design AF Nastase, JP Anand, AM Bender, D Montgomery, NW Griggs, ... Journal of medicinal chemistry 62 (8), 4193-4203, 2019 | 10 | 2019 |
| Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M1 Positive Allosteric Modulators JL Engers, AM Bender, JJ Kalbfleisch, HP Cho, KS Lingenfelter, ... ACS chemical neuroscience 10 (3), 1035-1042, 2018 | 10 | 2018 |
| Discovery and Optimization of Potent and CNS Penetrant M5-Preferring Positive Allosteric Modulators Derived from a Novel, Chiral N-(Indanyl)piperidine Amide … AM Bender, HP Cho, KD Nance, KS Lingenfelter, VB Luscombe, ... ACS chemical neuroscience 9 (7), 1572-1581, 2018 | 10 | 2018 |
| Isoquinoline amide and isoquinoline amide-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction PJ Conn, CW Lindsley, CR Hopkins, A Felts, AM Bender US Patent 10,710,997, 2020 | 9 | 2020 |
| Structure–Activity Relationships of Pan-Gαq/11 Coupled Muscarinic Acetylcholine Receptor Positive Allosteric Modulators AE Berizzi, AM Bender, CW Lindsley, PJ Conn, PM Sexton, CJ Langmead, ... ACS chemical neuroscience 9 (7), 1818-1828, 2018 | 9 | 2018 |
| Discovery of VU6028418: A Highly Selective and Orally Bioavailable M4 Muscarinic Acetylcholine Receptor Antagonist M Spock, TR Carter, KA Bollinger, C Han, LA Baker, AL Rodriguez, ... ACS Medicinal Chemistry Letters 12 (8), 1342-1349, 2021 | 7 | 2021 |
