| Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson’s disease S Grealish, E Diguet, A Kirkeby, B Mattsson, A Heuer, Y Bramoulle, ... Cell stem cell 15 (5), 653-665, 2014 | 471 | 2014 |
| Predictive markers guide differentiation to improve graft outcome in clinical translation of hESC-based therapy for Parkinson’s disease A Kirkeby, S Nolbrant, K Tiklova, A Heuer, N Kee, T Cardoso, ... Cell stem cell 20 (1), 135-148, 2017 | 277 | 2017 |
| Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation S Nolbrant, A Heuer, M Parmar, A Kirkeby Nature protocols 12 (9), 1962-1979, 2017 | 220 | 2017 |
| Activin A directs striatal projection neuron differentiation of human pluripotent stem cells C Arber, SV Precious, S Cambray, JR Risner-Janiczek, C Kelly, Z Noakes, ... Development 142 (7), 1375-1386, 2015 | 183 | 2015 |
| Unilateral nigrostriatal 6-hydroxydopamine lesions in mice I: motor impairments identify extent of dopamine depletion at three different lesion sites A Heuer, GA Smith, MJ Lelos, EL Lane, SB Dunnett Behavioural brain research 228 (1), 30-43, 2012 | 120 | 2012 |
| Monosynaptic tracing using modified rabies virus reveals early and extensive circuit integration of human embryonic stem cell-derived neurons S Grealish, A Heuer, T Cardoso, A Kirkeby, M Jönsson, J Johansson, ... Stem cell reports 4 (6), 975-983, 2015 | 99 | 2015 |
| Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease K Tiklová, S Nolbrant, A Fiorenzano, ÅK Björklund, Y Sharma, A Heuer, ... Nature communications 11 (1), 2434, 2020 | 85 | 2020 |
| Derangement of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and extracellular signal-regulated kinase (ERK) dependent striatal plasticity in L-DOPA-induced dyskinesia M Cerovic, V Bagetta, V Pendolino, V Ghiglieri, S Fasano, I Morella, ... Biological psychiatry 77 (2), 106-115, 2015 | 75 | 2015 |
| Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: predicting l-DOPA-induced dyskinesia GA Smith, A Heuer, SB Dunnett, EL Lane Behavioural brain research 226 (1), 281-292, 2012 | 69 | 2012 |
| DREADD modulation of transplanted DA neurons reveals a novel parkinsonian dyskinesia mechanism mediated by the serotonin 5-HT6 receptor P Aldrin-Kirk, A Heuer, G Wang, B Mattsson, M Lundblad, M Parmar, ... Neuron 90 (5), 955-968, 2016 | 61 | 2016 |
| IAP-based cell sorting results in homogeneous transplantable dopaminergic precursor cells derived from human pluripotent stem cells D Lehnen, S Barral, T Cardoso, S Grealish, A Heuer, A Smiyakin, ... Stem Cell Reports 9 (4), 1207-1220, 2017 | 55 | 2017 |
| Selective cognitive impairment in the YAC128 Huntington's disease mouse SP Brooks, N Janghra, GV Higgs, Z Bayram-Weston, A Heuer, L Jones, ... Brain research bulletin 88 (2-3), 121-129, 2012 | 54 | 2012 |
| Increased efficacy of the 6-hydroxydopamine lesion of the median forebrain bundle in small rats, by modification of the stereotaxic coordinates EM Torres, EL Lane, A Heuer, GA Smith, E Murphy, SB Dunnett Journal of neuroscience methods 200 (1), 29-35, 2011 | 50 | 2011 |
| Chemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum P Aldrin-Kirk, A Heuer, DR Ottosson, M Davidsson, B Mattsson, ... Neurobiology of disease 109, 148-162, 2018 | 46 | 2018 |
| AAV production everywhere: a simple, fast, and reliable protocol for in‐house AAV vector production based on chloroform extraction M Negrini, G Wang, A Heuer, T Björklund, M Davidsson Current Protocols in Neuroscience 93 (1), e103, 2020 | 35 | 2020 |
| Seeding of protein aggregation causes cognitive impairment in rat model of cortical synucleinopathy E Espa, EKH Clemensson, KC Luk, A Heuer, T Björklund, MA Cenci Movement Disorders 34 (11), 1699-1710, 2019 | 34 | 2019 |
| Dopamine-rich grafts alleviate deficits in contralateral response space induced by extensive dopamine depletion in rats A Heuer, MJ Lelos, CM Kelly, EM Torres, SB Dunnett Experimental neurology 247, 485-495, 2013 | 25 | 2013 |
| Comparison of 6‐hydroxydopamine lesions of the substantia nigra and the medial forebrain bundle on a lateralised choice reaction time task in mice A Heuer, GA Smith, SB Dunnett European Journal of Neuroscience 37 (2), 294-302, 2013 | 25 | 2013 |
| Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism … M Chumarina, K Russ, C Azevedo, A Heuer, M Pihl, A Collin, EÅ Frostner, ... Acta neuropathologica communications 7, 1-19, 2019 | 22 | 2019 |
| A comparison of AAV-vector production methods for gene therapy and preclinical assessment M Davidsson, M Negrini, S Hauser, A Svanbergsson, M Lockowandt, ... Scientific reports 10 (1), 21532, 2020 | 21 | 2020 |
