| Genomic and transcriptomic features of response to anti-PD-1 therapy in metastatic melanoma W Hugo, JM Zaretsky, LU Sun, C Song, BH Moreno, S Hu-Lieskovan, ... Cell 165 (1), 35-44, 2016 | 2976 | 2016 |
| Mutations associated with acquired resistance to PD-1 blockade in melanoma JM Zaretsky, A Garcia-Diaz, DS Shin, H Escuin-Ordinas, W Hugo, ... New England Journal of Medicine 375 (9), 819-829, 2016 | 2932 | 2016 |
| Melanomas acquire resistance to B-RAF (V600E) inhibition by RTK or N-RAS upregulation R Nazarian, H Shi, QI Wang, X Kong, RC Koya, H Lee, Z Chen, MK Lee, ... Nature 468 (7326), 973-977, 2010 | 2586 | 2010 |
| RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF (V600E) PI Poulikakos, Y Persaud, M Janakiraman, X Kong, C Ng, G Moriceau, ... Nature 480 (7377), 387-390, 2011 | 1626 | 2011 |
| RAS Mutations in Cutaneous Squamous-Cell Carcinomas in Patients Treated with BRAF Inhibitors F Su, A Viros, C Milagre, K Trunzer, G Bollag, O Spleiss, JS Reis-Filho, ... New England Journal of Medicine 366 (3), 207-215, 2012 | 1194 | 2012 |
| Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy H Shi, W Hugo, X Kong, A Hong, RC Koya, G Moriceau, T Chodon, R Guo, ... Cancer discovery 4 (1), 80-93, 2014 | 1044 | 2014 |
| Melanoma whole-exome sequencing identifies V600EB-RAF amplification-mediated acquired B-RAF inhibitor resistance H Shi, G Moriceau, X Kong, MK Lee, H Lee, RC Koya, C Ng, T Chodon, ... Nature communications 3 (1), 724, 2012 | 813 | 2012 |
| Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma J Müller, O Krijgsman, J Tsoi, L Robert, W Hugo, C Song, X Kong, ... Nature communications 5 (1), 5712, 2014 | 632 | 2014 |
| Non-genomic and immune evolution of melanoma acquiring MAPKi resistance W Hugo, H Shi, LU Sun, M Piva, C Song, X Kong, G Moriceau, A Hong, ... Cell 162 (6), 1271-1285, 2015 | 605 | 2015 |
| Therapy-induced tumour secretomes promote resistance and tumour progression AC Obenauf, Y Zou, AL Ji, S Vanharanta, W Shu, H Shi, X Kong, ... Nature 520 (7547), 368-372, 2015 | 483 | 2015 |
| Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in melanoma drug addiction G Moriceau, W Hugo, A Hong, H Shi, X Kong, CY Clarissa, RC Koya, ... Cancer cell 27 (2), 240-256, 2015 | 371 | 2015 |
| Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms DB Johnson, AM Menzies, L Zimmer, Z Eroglu, F Ye, S Zhao, H Rizos, ... European journal of cancer 51 (18), 2792-2799, 2015 | 334 | 2015 |
| Combinatorial treatments that overcome PDGFRβ-driven resistance of melanoma cells to V600EB-RAF inhibition H Shi, X Kong, A Ribas, RS Lo Cancer research 71 (15), 5067-5074, 2011 | 277 | 2011 |
| Polymer nanofiber‐embedded microchips for detection, isolation, and molecular analysis of single circulating melanoma cells S Hou, L Zhao, Q Shen, J Yu, C Ng, X Kong, D Wu, M Song, X Shi, X Xu, ... Angewandte Chemie 125 (12), 3463-3467, 2013 | 245 | 2013 |
| A novel AKT1 mutant amplifies an adaptive melanoma response to BRAF inhibition H Shi, A Hong, X Kong, RC Koya, C Song, G Moriceau, W Hugo, CC Yu, ... Cancer discovery 4 (1), 69-79, 2014 | 182 | 2014 |
| Recurrent tumor cell–intrinsic and–extrinsic alterations during MAPKi-induced melanoma regression and early adaptation C Song, M Piva, LU Sun, A Hong, G Moriceau, X Kong, H Zhang, S Lomeli, ... Cancer discovery 7 (11), 1248-1265, 2017 | 154 | 2017 |
| Preexisting MEK1 Exon 3 Mutations in V600E/KBRAF Melanomas Do Not Confer Resistance to BRAF Inhibitors H Shi, G Moriceau, X Kong, RC Koya, R Nazarian, GM Pupo, ... Cancer discovery 2 (5), 414-424, 2012 | 114 | 2012 |
| Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy. Cancer Discov. 2014; 4: 80–93. doi: 10.1158/2159-8290 H Shi, W Hugo, X Kong, A Hong, RC Koya, G Moriceau, T Chodon, R Guo, ... CD-13-0642.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 111 | |
| Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors AA Marusiak, ZC Edwards, W Hugo, EW Trotter, MR Girotti, ... Nature communications 5 (1), 3901, 2014 | 84 | 2014 |
| JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma B Titz, A Lomova, A Le, W Hugo, X Kong, J Ten Hoeve, M Friedman, H Shi, ... Cell discovery 2 (1), 1-19, 2016 | 68 | 2016 |
Shi HubingUCLAVerified email at scu.edu.cn
Shi HubingUCLAVerified email at scu.edu.cn