Clive Holmes
Clive Holmes
Emeritus Professor of Biological Psychiatry
Verified email at
Cited by
Cited by
Neuroinflammation in Alzheimer's disease
MT Heneka, MJ Carson, J El Khoury, GE Landreth, F Brosseron, ...
The Lancet Neurology 14 (4), 388-405, 2015
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ...
Nature genetics 45 (12), 1452-1458, 2013
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ...
Nature genetics 41 (10), 1088-1093, 2009
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ...
Nature genetics 43 (5), 429-435, 2011
Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
C Holmes, D Boche, D Wilkinson, G Yadegarfar, V Hopkins, A Bayer, ...
The Lancet 372 (9634), 216-223, 2008
Microglia in neurodegenerative disease
VH Perry, JAR Nicoll, C Holmes
Nature Reviews Neurology 6 (4), 193-201, 2010
Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report
JAR Nicoll, D Wilkinson, C Holmes, P Steart, H Markham, RO Weller
Nature medicine 9 (4), 448-452, 2003
Systemic inflammation and disease progression in Alzheimer disease
C Holmes, C Cunningham, E Zotova, J Woolford, C Dean, S Kerr, ...
Neurology 73 (10), 768-774, 2009
Systemic infections and inflammation affect chronic neurodegeneration
VH Perry, C Cunningham, C Holmes
Nature Reviews Immunology 7 (2), 161-167, 2007
Microglial priming in neurodegenerative disease
VH Perry, C Holmes
Nature Reviews Neurology 10 (4), 217-224, 2014
The Montreal Cognitive Assessment: validity and utility in a memory clinic setting
T Smith, N Gildeh, C Holmes
The Canadian Journal of Psychiatry 52 (5), 329-332, 2007
New insights into the genetic etiology of Alzheimer’s disease and related dementias
C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ...
Nature genetics 54 (4), 412-436, 2022
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
Donepezil and memantine for moderate-to-severe Alzheimer's disease
R Howard, R McShane, J Lindesay, C Ritchie, A Baldwin, R Barber, ...
New England Journal of Medicine 366 (10), 893-903, 2012
The epidemiology of DSM-III-R bipolar I disorder in a general population survey
RC Kessler, DR Rubinow, C Holmes, JM Abelson, S Zhao
Bipolar Disorder, 11-21, 2019
Sensitivity and specificity of dopamine transporter imaging with 123I-FP-CIT SPECT in dementia with Lewy bodies: a phase III, multicentre study
I McKeith, J O'Brien, Z Walker, K Tatsch, J Booij, J Darcourt, A Padovani, ...
The Lancet Neurology 6 (4), 305-313, 2007
Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial
S Banerjee, J Hellier, M Dewey, R Romeo, C Ballard, R Baldwin, ...
The Lancet 378 (9789), 403-411, 2011
Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease
C Cruchaga, CM Karch, SC Jin, BA Benitez, Y Cai, R Guerreiro, O Harari, ...
Nature 505 (7484), 550-554, 2014
Validity of current clinical criteria for Alzheimer's disease, vascular dementia and dementia with Lewy bodies
C Holmes, N Cairns, PL Lantos, A Mann
The British Journal of Psychiatry 174 (1), 45-50, 1999
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