Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus DJ Downes, AR Cross, P Hua, N Roberts, R Schwessinger, AJ Cutler, ... Nature genetics 53 (11), 1606-1615, 2021 | 135 | 2021 |
Defining genome architecture at base-pair resolution P Hua, M Badat, LLP Hanssen, LD Hentges, N Crump, DJ Downes, ... Nature 595 (7865), 125-129, 2021 | 111 | 2021 |
BET inhibition disrupts transcription but retains enhancer-promoter contact NT Crump, E Ballabio, L Godfrey, R Thorne, E Repapi, J Kerry, M Tapia, ... Nature communications 12 (1), 223, 2021 | 104 | 2021 |
Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs S O’Byrne, N Elliott, S Rice, G Buck, N Fordham, C Garnett, L Godfrey, ... Blood, The Journal of the American Society of Hematology 134 (13), 1059-1071, 2019 | 65 | 2019 |
Morphine delays the onset of action of prasugrel in patients with prior history of ST-elevation myocardial infarction MR Thomas, AC Morton, R Hossain, B Chen, L Luo, NNBM Shahari, ... Thrombosis and haemostasis 116 (07), 96-102, 2016 | 65 | 2016 |
Analysis of sub-kilobase chromatin topology reveals nano-scale regulatory interactions with variable dependence on cohesin and CTCF A Aljahani, P Hua, MA Karpinska, K Quililan, JOJ Davies, AM Oudelaar Nature communications 13 (1), 2139, 2022 | 58 | 2022 |
CD70 expression determines the therapeutic efficacy of expanded human regulatory T cells R Arroyo Hornero, C Georgiadis, P Hua, D Trzupek, LZ He, W Qasim, ... Communications biology 3 (1), 375, 2020 | 50 | 2020 |
Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development A Roy, G Wang, D Iskander, S O’Byrne, N Elliott, J O’Sullivan, G Buck, ... Cell Reports 36 (11), 2021 | 38 | 2021 |
CHIP facilitates ubiquitination of inducible nitric oxide synthase and promotes its proteasomal degradation L Chen, X Kong, J Fu, Y Xu, S Fang, P Hua, L Luo, Z Yin Cellular immunology 258 (1), 38-43, 2009 | 30 | 2009 |
The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes P Hua, J Hester, G Adigbli, R Li, B Psaila, A Roy, CJR Bataille, GM Wynne, ... Blood, The Journal of the American Society of Hematology 136 (21), 2410-2415, 2020 | 26 | 2020 |
Reactivation of a developmentally silenced embryonic globin gene AJ King, D Songdej, DJ Downes, RA Beagrie, S Liu, M Buckley, P Hua, ... Nature communications 12 (1), 4439, 2021 | 24 | 2021 |
Single-cell analysis of bone marrow–derived CD34+ cells from children with sickle cell disease and thalassemia P Hua, N Roy, J de la Fuente, G Wang, S Thongjuea, K Clark, A Roy, ... Blood, The Journal of the American Society of Hematology 134 (23), 2111-2115, 2019 | 22 | 2019 |
A novel high-throughput screening platform reveals an optimized cytokine formulation for human hematopoietic progenitor cell expansion M Tarunina, D Hernandez, B Kronsteiner-Dobramysl, P Pratt, T Watson, ... Stem cells and development 25 (22), 1709-1720, 2016 | 16 | 2016 |
A modified CD34+ hematopoietic stem and progenitor cell isolation strategy from cryopreserved human umbilical cord blood MF Mata, D Hernandez, E Rologi, D Grandolfo, E Hassan, P Hua, ... Transfusion 59 (12), 3560-3569, 2019 | 13 | 2019 |
Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion P Hua, B Kronsteiner, M van der Garde, N Ashley, D Hernandez, ... Scientific reports 9 (1), 5300, 2019 | 12 | 2019 |
Development of LT-HSC-Reconstituted Non-Irradiated NBSGW Mice for the Study of Human Hematopoiesis In Vivo G Adigbli, P Hua, M Uchiyama, I Roberts, J Hester, SM Watt, F Issa Frontiers in Immunology 12, 642198, 2021 | 10 | 2021 |
Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability? AT Merryweather-Clarke, D Cook, BJ Lara, P Hua, E Repapi, N Ashley, ... Stem Cell Research & Therapy 9, 1-15, 2018 | 9 | 2018 |
Direct correction of haemoglobin E β-thalassaemia using base editors M Badat, A Ejaz, P Hua, S Rice, W Zhang, LD Hentges, CA Fisher, ... Nature Communications 14 (1), 2238, 2023 | 7 | 2023 |
Increasing complexity of molecular landscapes in human hematopoietic stem and progenitor cells during development and aging SM Watt, P Hua, I Roberts International Journal of Molecular Sciences 23 (7), 3675, 2022 | 6 | 2022 |
COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium, Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus DJ Downes, AR Cross, P Hua, N Roberts, R Schwessinger, AJ Cutler, ... Nat. Genet 53, 1606-1615, 2021 | 5 | 2021 |