| Remote, 1, 5-Anti stereoinduction in the boron-mediated aldol reactions of β-oxygenated methyl ketones I Paterson, KR Gibson, RM Oballa Tetrahedron letters 37 (47), 8585-8588, 1996 | 253 | 1996 |
| Rapid discovery of a novel series of Abl kinase inhibitors by application of an integrated microfluidic synthesis and screening platform B Desai, K Dixon, E Farrant, Q Feng, KR Gibson, WP van Hoorn, J Mills, ... Journal of medicinal chemistry 56 (7), 3033-3047, 2013 | 157 | 2013 |
| Stereocontrolled Total Synthesis of (+)‐Altohyrtin A/Spongistatin 1 I Paterson, DYK Chen, MJ Coster, JL Aceña, J Bach, KR Gibson, ... Angewandte Chemie International Edition 40 (21), 4055-4060, 2001 | 148 | 2001 |
| Studies in marine macrolide synthesis: Synthesis of a C16 C28 subunit of spongistatin 1 (altohyrtin A) incorporating the CD-spiroacetal moiety I Paterson, DJ Wallace, KR Gibson Tetrahedron letters 38 (51), 8911-8914, 1997 | 102 | 1997 |
| Metabolism, pharmacokinetics and toxicity of functional groups: impact of chemical building blocks on ADMET DA Smith Royal Society of Chemistry, 2010 | 79* | 2010 |
| The discovery of a potent, selective, and peripherally restricted pan-Trk inhibitor (PF-06273340) for the treatment of pain SE Skerratt, M Andrews, SK Bagal, J Bilsland, D Brown, PJ Bungay, ... Journal of Medicinal Chemistry 59 (22), 10084-10099, 2016 | 75 | 2016 |
| Novel amino-pyrazole ureas with potent in vitro and in vivo antileishmanial activity CE Mowbray, S Braillard, W Speed, PA Glossop, GA Whitlock, KR Gibson, ... Journal of medicinal chemistry 58 (24), 9615-9624, 2015 | 71 | 2015 |
| Metabolism, pharmacokinetics and toxicity of functional groups: impact of chemical building blocks on ADMET DA Smith Royal Society of Chemistry, 2010 | 67 | 2010 |
| The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the CD-spiroacetal segment I Paterson, MJ Coster, DYK Chen, KR Gibson, DJ Wallace Organic & Biomolecular Chemistry 3 (13), 2410-2419, 2005 | 67 | 2005 |
| Quantitative chemical proteomic profiling of ubiquitin specific proteases in intact cancer cells JA Ward, L McLellan, M Stockley, KR Gibson, GA Whitlock, C Knights, ... ACS chemical biology 11 (12), 3268-3272, 2016 | 55 | 2016 |
| Total Synthesis of cis-Sylvaticin LJ Brown, IB Spurr, SC Kemp, NP Camp, KR Gibson, RCD Brown Organic Letters 10 (12), 2489-2492, 2008 | 52 | 2008 |
| Discovery and Optimization of Selective Nav1.8 Modulator Series That Demonstrate Efficacy in Preclinical Models of Pain SK Bagal, PJ Bungay, SM Denton, KR Gibson, MS Glossop, TL Hay, ... ACS medicinal chemistry letters 6 (6), 650-654, 2015 | 44 | 2015 |
| Synthesis and conformational dynamics of tricyclic pyridones containing a fused seven-membered ring KR Gibson, L Hitzel, RJ Mortishire-Smith, U Gerhard, RA Jelley, AJ Reeve, ... The Journal of Organic Chemistry 67 (26), 9354-9360, 2002 | 43 | 2002 |
| Design and Identification of a Novel, Functionally Subtype Selective GABAA Positive Allosteric Modulator (PF-06372865) RM Owen, D Blakemore, L Cao, N Flanagan, R Fish, KR Gibson, ... Journal of Medicinal Chemistry 62 (12), 5773-5796, 2019 | 35 | 2019 |
| 2-PYRIDINE CARBOXAMIDE DERIVATIVES AS SODIUM CHANNEL MODULATORS SK Bagal, KR Gibson, MI Kemp, C Poinsard, BL Stammen, SM Denton, ... EP Patent 2,183,241, 2012 | 34* | 2012 |
| 2-PYRIDINE CARBOXAMIDE DERIVATIVES AS SODIUM CHANNEL MODULATORS S BAGAL, K GIBSON, M KEMP, C POINSARD, B STAMMEN, S DENTON, ... WO Patent 2,008,135,826, 2008 | 34* | 2008 |
| Preclinical and clinical pharmacokinetics of PF-02413873, a nonsteroidal progesterone receptor antagonist PJ Bungay, S Tweedy, DC Howe, KR Gibson, HM Jones, NM Mount Drug metabolism and disposition 39 (8), 1396-1405, 2011 | 28 | 2011 |
| Tricyclic pyridones as functionally selective human GABAAα2/3 receptor-ion channel ligands J Crawforth, JR Atack, SM Cook, KR Gibson, A Nadin, AP Owens, A Pike, ... Bioorganic & medicinal chemistry letters 14 (7), 1679-1682, 2004 | 24 | 2004 |
| 3-Substituted gem-cyclohexane sulfone based γ-secretase inhibitors for Alzheimer’s disease: Conformational analysis and biological activity RA Jelley, J Elliott, KR Gibson, T Harrison, D Beher, EE Clarke, HD Lewis, ... Bioorganic & medicinal chemistry letters 16 (14), 3839-3842, 2006 | 21 | 2006 |
| In vitro and in vivo SAR of pyrido [3, 4-d] pyramid-4-ylamine based mGluR1 antagonists SJ Mantell, KR Gibson, SA Osborne, GN Maw, H Rees, PG Dodd, ... Bioorganic & medicinal chemistry letters 19 (8), 2190-2194, 2009 | 20 | 2009 |
Gavin WhitlockSandexisVerified email at sandexis.co.uk
