John Hamlyn
John Hamlyn
Professor of Physiology, University of Maryland
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TitleCited byYear
Identification and characterization of a ouabain-like compound from human plasma
JM Hamlyn, MP Blaustein, S Bova, DW DuCharme, DW Harris, F Mandel, ...
Proceedings of the National Academy of Sciences 88 (14), 6259-6263, 1991
A circulating inhibitor of (Na++ K+) ATPase associated with essential hypertension
JM Hamlyn, R Ringel, J Schaeffer, PD Levinson, BP Hamilton, ...
Nature 300 (5893), 650, 1982
Mass spectral characterization of an endogenous digitalislike factor from human plasma.
WR Mathews, DW DuCharme, JM Hamlyn, DW Harris, F Mandel, ...
Hypertension 17 (6_pt_2), 930-935, 1991
Elevated concentrations of endogenous ouabain in patients with congestive heart failure.
SS Gottlieb, AC Rogowski, M Weinberg, CM Krichten, BP Hamilton, ...
Circulation 86 (2), 420-425, 1992
How NaCl raises blood pressure: a new paradigm for the pathogenesis of salt-dependent hypertension
MP Blaustein, FHH Leenen, L Chen, VA Golovina, JM Hamlyn, TL Pallone, ...
American Journal of Physiology-Heart and Circulatory Physiology 302 (5 …, 2011
Endogenous ouabain, sodium balance and blood pressure: a review and a hypothesis.
JM Hamlyn, BP Hamilton, P Manunta
Journal of hypertension 14 (2), 151-167, 1996
Sodium transport inhibition, cell calcium, and hypertension: the natriuretic hormone/Na+-Ca2+ exchange/hypertension hypothesis
MP Blaustein, JM Hamlyn
The American journal of medicine 77 (4), 45-59, 1984
Ouabain is secreted by bovine adrenocortical cells
J Laredo, BP Hamilton, JM Hamlyn
Endocrinology 135 (2), 794-797, 1994
Left ventricular mass, stroke volume, and ouabain-like factor in essential hypertension
P Manunta, P Stella, R Rivera, D Ciurlino, D Cusi, M Ferrandi, JM Hamlyn, ...
Hypertension 34 (3), 450-456, 1999
Purification of an endogenous digitalislike factor from human plasma for structural analysis.
JH Ludens, MA Clark, DW DuCharme, DW Harris, BS Lutzke, F Mandel, ...
Hypertension 17 (6_pt_2), 923-929, 1991
Ouabain-induced hypertension in the rat: relationships among plasma and tissue ouabain and blood pressure
P Manunta, AC Rogowski, BP Hamilton, JM Hamlyn
Journal of hypertension 12 (5), 549-560, 1994
Sodium pump α2 subunits control myogenic tone and blood pressure in mice
J Zhang, MY Lee, M Cavalli, L Chen, R Berra‐Romani, CW Balke, ...
The Journal of physiology 569 (1), 243-256, 2005
Long-term ouabain administration produces hypertension in rats.
CM Yuan, P Manunta, JM Hamlyn, S Chen, E Bohen, J Yeun, FJ Haddy, ...
Hypertension 22 (2), 178-187, 1993
Observations on the nature, biosynthesis, secretion and significance of endogenous ouabain
JM Hamlyn, ZR Lu, P Manunta, JH Ludens, K Kimura, JR Shah, J Laredo, ...
Clinical and experimental hypertension 20 (5-6), 523-533, 1998
Ouabain augments Ca2+ transients in arterial smooth muscle without raising cytosolic Na+
A Arnon, JM Hamlyn, MP Blaustein
American Journal of Physiology-Heart and Circulatory Physiology 279 (2 …, 2000
Ouabain, digitalis-like factors and hypertension.
JM Hamlyn, P Manunta
Journal of hypertension. Supplement: official journal of the International …, 1992
Role of a natriuretic factor in essential hypertension: an hypothesis
Annals of Internal Medicine 98 (5_Part_2), 785-792, 1983
The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension
MP Blaustein, J Zhang, L Chen, H Song, H Raina, SP Kinsey, M Izuka, ...
Hypertension 53 (2), 291-298, 2009
Angiotensin II stimulates secretion of endogenous ouabain from bovine adrenocortical cells via angiotensin type 2 receptors
J Laredo, JR Shah, Z Lu, BP Hamilton, JM Hamlyn
Hypertension 29 (1), 401-407, 1997
Immunoreactive endogenous ouabain in primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels.
GP Rossi, P Manunta, JM Hamlyn, E Pavan, RT De, A Semplicini, ...
Journal of hypertension 13 (10), 1181-1191, 1995
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