A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice AA Toye, JD Lippiat, P Proks, K Shimomura, L Bentley, A Hugill, V Mijat, ... Diabetologia 48, 675-686, 2005 | 516 | 2005 |
Molecular basis of Kir6. 2 mutations associated with neonatal diabetes or neonatal diabetes plus neurological features P Proks, JF Antcliff, J Lippiat, AL Gloyn, AT Hattersley, FM Ashcroft Proceedings of the National Academy of Sciences 101 (50), 17539-17544, 2004 | 283 | 2004 |
Affimer proteins are versatile and renewable affinity reagents C Tiede, R Bedford, SJ Heseltine, G Smith, I Wijetunga, R Ross, ... Elife 6, e24903, 2017 | 220 | 2017 |
Activation of the Cl− channel ANO1 by localized calcium signals in nociceptive sensory neurons requires coupling with the IP3 receptor X Jin, S Shah, Y Liu, H Zhang, M Lees, Z Fu, JD Lippiat, DJ Beech, ... Science signaling 6 (290), ra73-ra73, 2013 | 212 | 2013 |
Properties of BKCa Channels Formed by Bicistronic Expression of hSloα and β1–4 Subunits in HEK293 Cells JD Lippiat, NB Standen, ID Harrow, SC Phillips, NW Davies The Journal of membrane biology 192, 141-148, 2003 | 123 | 2003 |
Constitutively active TRPC channels of adipocytes confer a mechanism for sensing dietary fatty acids and regulating adiponectin P Sukumar, A Sedo, J Li, LA Wilson, D O'Regan, JD Lippiat, KE Porter, ... Circulation research 111 (2), 191-200, 2012 | 100 | 2012 |
Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients CM Gorvin, MJ Wilmer, SE Piret, B Harding, LP Van Den Heuvel, O Wrong, ... Proceedings of the National Academy of Sciences 110 (17), 7014-7019, 2013 | 98 | 2013 |
CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease AAC Reed, NY Loh, S Terryn, JD Lippiat, C Partridge, J Galvanovskis, ... American Journal of Physiology-Renal Physiology 298 (2), F365-F380, 2010 | 77 | 2010 |
Mutations at the same residue (R50) of Kir6. 2 (KCNJ11) that cause neonatal diabetes produce different functional effects K Shimomura, CAJ Girard, P Proks, J Nazim, JD Lippiat, F Cerutti, R Lorini, ... Diabetes 55 (6), 1705-1712, 2006 | 76 | 2006 |
Characterization of Dent's disease mutations of CLC-5 reveals a correlation between functional and cell biological consequences and protein structure AJ Smith, AAC Reed, NY Loh, RV Thakker, JD Lippiat American Journal of Physiology-Renal Physiology 296 (2), F390-F397, 2009 | 73 | 2009 |
Carrier-mediated transport of quercetin conjugates: Involvement of organic anion transporters and organic anion transporting polypeptides CC Wong, Y Akiyama, T Abe, JD Lippiat, C Orfila, G Williamson Biochemical pharmacology 84 (4), 564-570, 2012 | 66 | 2012 |
The changing landscape of membrane protein structural biology through developments in electron microscopy S Rawson, S Davies, JD Lippiat, SP Muench Molecular membrane biology 33 (1-2), 12-22, 2016 | 61 | 2016 |
Direct endosomal acidification by the outwardly rectifying CLC‐5 Cl−/H+ exchanger AJ Smith, JD Lippiat The Journal of Physiology 588 (12), 2033-2045, 2010 | 61 | 2010 |
Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets C Kapsalis, B Wang, H El Mkami, SJ Pitt, JR Schnell, TK Smith, JD Lippiat, ... Nature Communications 10 (1), 4619, 2019 | 60 | 2019 |
Mutational analysis of CLC-5, cofilin and CLC-4 in patients with Dent’s disease F Wu, AAC Reed, SE Williams, NY Loh, JD Lippiat, PT Christie, O Large, ... Nephron Physiology 112 (4), p53-p62, 2009 | 59 | 2009 |
ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6. 2 revealed by fluorescence resonance energy transfer T Tsuboi, JD Lippiat, FM Ashcroft, GA Rutter Proceedings of the National Academy of Sciences 101 (1), 76-81, 2004 | 58 | 2004 |
Differential patterns of inhibition of the sugar transporters GLUT2, GLUT5 and GLUT7 by flavonoids JS Gauer, S Tumova, JD Lippiat, A Kerimi, G Williamson Biochemical pharmacology 152, 11-20, 2018 | 57 | 2018 |
Constitutive endocytic recycling and protein kinase C-mediated lysosomal degradation control KATP channel surface density PT Manna, AJ Smith, TK Taneja, GJ Howell, JD Lippiat, A Sivaprasadarao Journal of Biological Chemistry 285 (8), 5963-5973, 2010 | 57 | 2010 |
Membrane ion channels and diabetes P Proks, JD Lippiat Current pharmaceutical design 12 (4), 485-501, 2006 | 56 | 2006 |
Whole-cell recording using the perforated patch clamp technique JD Lippiat Potassium Channels: Methods and Protocols, 141-149, 2009 | 55 | 2009 |