Jens Bunt
Jens Bunt
Senior Researcher at Princess Máxima Center for Pediatric Oncology
Verified email at - Homepage
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Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features
M Kool, J Koster, J Bunt, NE Hasselt, A Lakeman, P Van Sluis, D Troost, ...
PloS one 3 (8), e3088, 2008
Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing
V Hovestadt, DTW Jones, S Picelli, W Wang, M Kool, PA Northcott, ...
Nature 510 (7506), 537-541, 2014
OTX2 directly activates cell cycle genes and inhibits differentiation in medulloblastoma cells
J Bunt, NE Hasselt, DA Zwijnenburg, M Hamdi, J Koster, R Versteeg, ...
International journal of cancer 131 (2), E21-E32, 2012
Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance
APL Marsh, D Heron, TJ Edwards, A Quartier, C Galea, C Nava, ...
Nature genetics 49 (4), 511-514, 2017
Astroglial-mediated remodeling of the interhemispheric midline is required for the formation of the corpus callosum
I Gobius, L Morcom, R Suárez, J Bunt, P Bukshpun, W Reardon, ...
Cell reports 17 (3), 735-747, 2016
Identification of CUX1 as the recurrent chromosomal band 7q22 target gene in human uterine leiomyoma
EFPM Schoenmakers, J Bunt, L Hermers, M Schepens, G Merkx, ...
Genes, Chromosomes and Cancer 52 (1), 11-23, 2013
Regulation of cell cycle genes and induction of senescence by overexpression of OTX2 in medulloblastoma cell lines
J Bunt, TG de Haas, NE Hasselt, DA Zwijnenburg, J Koster, R Versteeg, ...
Molecular Cancer Research 8 (10), 1344-1357, 2010
MicroRNA-153 regulates the acquisition of gliogenic competence by neural stem cells
J Tsuyama, J Bunt, LJ Richards, H Iwanari, Y Mochizuki, T Hamakubo, ...
Stem cell reports 5 (3), 365-377, 2015
OTX2 sustains a bivalent-like state of OTX2-bound promoters in medulloblastoma by maintaining their H3K27me3 levels
J Bunt, NA Hasselt, DA Zwijnenburg, J Koster, R Versteeg, M Kool
Acta neuropathologica 125 (3), 385-394, 2013
The convergent roles of the nuclear factor I transcription factors in development and cancer
KS Chen, JWC Lim, LJ Richards, J Bunt
Cancer letters 410, 124-138, 2017
Pathogenic DDX3X mutations impair RNA metabolism and neurogenesis during fetal cortical development
AL Lennox, ML Hoye, R Jiang, BL Johnson-Kerner, LA Suit, ...
Neuron 106 (3), 404-420. e8, 2020
Joint binding of OTX2 and MYC in promotor regions is associated with high gene expression in medulloblastoma
J Bunt, NE Hasselt, DA Zwijnenburg, J Koster, R Versteeg, M Kool
PloS one 6 (10), e26058, 2011
Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord
E Matuzelski, J Bunt, D Harkins, JWC Lim, RM Gronostajski, LJ Richards, ...
Developmental biology 432 (2), 286-297, 2017
Nuclear factor one B (NFIB) encodes a subtype-specific tumour suppressor in glioblastoma
BW Stringer, J Bunt, BW Day, G Barry, PR Jamieson, KS Ensbey, ...
Oncotarget 7 (20), 29306, 2016
Differential neuronal and glial expression of nuclear factor I proteins in the cerebral cortex of adult mice
KS Chen, L Harris, JWC Lim, TJ Harvey, M Piper, RM Gronostajski, ...
Journal of Comparative Neurology 525 (11), 2465-2483, 2017
YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis
KW Pajtler, Y Wei, K Okonechnikov, PBG Silva, M Vouri, L Zhang, ...
Nature communications 10 (1), 1-16, 2019
EMX1 regulates NRP1-mediated wiring of the mouse anterior cingulate cortex
JWC Lim, ALS Donahoo, J Bunt, TJ Edwards, LR Fenlon, Y Liu, J Zhou, ...
Development 142 (21), 3746-3757, 2015
NFIB haploinsufficiency is associated with intellectual disability and macrocephaly
I Schanze, J Bunt, JWC Lim, D Schanze, RJ Dean, M Alders, P Blanchet, ...
The American Journal of Human Genetics 103 (5), 752-768, 2018
PAX6 does not regulate Nfia and Nfib expression during neocortical development
J Bunt, JWC Lim, L Zhao, S Mason, LJ Richards
Scientific reports 5 (1), 1-10, 2015
Combined allelic dosage of Nfia and Nfib regulates cortical development
J Bunt, JM Osinski, JWC Lim, D Vidovic, Y Ye, O Zalucki, TR O’Connor, ...
Brain and neuroscience advances 1, 2398212817739433, 2017
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