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Matthew Y. Tang
Matthew Y. Tang
Ottawa Hospital Research Institute, McGill, Montreal Neurological Institute
Verified email at ohri.ca
Title
Cited by
Cited by
Year
Structure of parkin reveals mechanisms for ubiquitin ligase activation
JF Trempe, V Sauvé, K Grenier, M Seirafi, MY Tang, M Ménade, ...
Science 340 (6139), 1451-1455, 2013
5412013
USP 8 regulates mitophagy by removing K 6‐linked ubiquitin conjugates from parkin
TM Durcan, MY Tang, JR Pérusse, EA Dashti, MA Aguileta, GL McLelland, ...
The EMBO journal 33 (21), 2473-2491, 2014
3752014
Defending the mitochondria: The pathways of mitophagy and mitochondrial-derived vesicles
RF Roberts, MY Tang, EA Fon, TM Durcan
The international journal of biochemistry & cell biology 79, 427-436, 2016
1132016
Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation
MY Tang, M Vranas, AI Krahn, S Pundlik, JF Trempe, EA Fon
Nature communications 8 (1), 14697, 2017
852017
The landscape of Parkin variants reveals pathogenic mechanisms and therapeutic targets in Parkinson’s disease
W Yi, EJ MacDougall, MY Tang, AI Krahn, Z Gan-Or, JF Trempe, EA Fon
Human molecular genetics 28 (17), 2811-2825, 2019
692019
Viral delivery of CAR targets to solid tumors enables effective cell therapy
A Aalipour, F Le Boeuf, M Tang, S Murty, F Simonetta, AX Lozano, ...
Molecular Therapy-Oncolytics 17, 232-240, 2020
462020
Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system
J Coulombe, P Gamage, MT Gray, M Zhang, MY Tang, J Woulfe, ...
Frontiers in aging neuroscience 6, 129, 2014
362014
Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death
ML De Snoo, EL Friesen, YT Zhang, R Earnshaw, G Dorval, M Kapadia, ...
Cell Death & Disease 10 (12), 907, 2019
332019
Experimental and Computational Analysis of Polyglutamine-Mediated Cytotoxicity
M Tang
University of Ottawa, 2012
172012
Experimental and computational analysis of polyglutamine-mediated cytotoxicity
MY Tang, CJ Proctor, J Woulfe, DA Gray
PLoS computational biology 6 (9), e1000944, 2010
172010
Delayed spinocerebellar ataxia in transgenic mice expressing mutant ubiquitin
M Tsirigotis, MY Tang, M Beyers, M Zhang, J Woulfe, DA Gray
Neuropathology and applied neurobiology 32 (1), 26-39, 2006
172006
Activation of p38MAPK contributes to expanded polyglutamine-induced cytotoxicity
M Tsirigotis, RM Baldwin, MY Tang, IAJ Lorimer, DA Gray
PloS one 3 (5), e2130, 2008
142008
Protective effects of mutant ubiquitin in transgenic mice
DA Gray, M Tsirigotis, J Brun, M Tang, M Zhang, M Beyers, J Woulfe
Annals of the New York Academy of Sciences 1019 (1), 215-218, 2004
122004
CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX
JT Whelan, R Singaravelu, F Wang, A Pelin, LA Tamming, G Pugliese, ...
Frontiers in Immunology 13, 1050250, 2023
32023
Abstract PR19: utilizing novel oncolytic vaccinia virus for selective expression of immunotherapeutic payloads in metastatic tumors
A Pelin, M Huh, M Tang, F LeBouef, B Keller, J Duong, K Knowles, ...
Cancer Immunology Research 8 (4_Supplement), PR19-PR19, 2020
22020
Modified vaccinia vectors
JC Bell, F Le Boeuf, BA KELLER, A PELIN
US Patent App. 17/694,115, 2023
12023
Modified orthopoxvirus vectors
JC Bell, A PELIN, CJ BREITBACH, MF BURGESS, SH BERNSTEIN
US Patent App. 17/415,606, 2022
12022
Abstract B101: Novel oncolytic vaccinia virus platform for systemic delivery of immunotherapeutic payloads
JC Bell, A Pelin, M Huh, M Tang, FL Boeuf, B Keller, J Duong, ...
Cancer Immunology Research 7 (2_Supplement), B101-B101, 2019
12019
Dysfunction of the Ubiquitin/Proteasome System and Mitochondria in Neurodegenerative Disease
MY Tang, DA Gray
Mitochondrial Dysfunction in Neurodegenerative Disorders, 141-155, 2012
12012
Structure and dynamics of pathway activation by the Toll immunoreceptor from the viral mosquito vector Aedes aegypti
M Gangloff, Y Saucereau, T Wilson, M Tang, M Moncrieffe, S Hardwick, ...
2021
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