Follow
Matthew David Zimmerman
Matthew David Zimmerman
Instructor
Verified email at iwonka.med.virginia.edu - Homepage
Title
Cited by
Cited by
Year
Structural and immunologic characterization of bovine, horse, and rabbit serum albumins
KA Majorek, PJ Porebski, A Dayal, MD Zimmerman, K Jablonska, ...
Molecular immunology 52 (3-4), 174-182, 2012
10192012
The association between sterilizing activity and drug distribution into tuberculosis lesions
B Prideaux, LE Via, MD Zimmerman, S Eum, J Sarathy, P O'brien, C Chen, ...
Nature medicine 21 (10), 1223-1227, 2015
4662015
A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats
N Beloglazova, G Brown, MD Zimmerman, M Proudfoot, KS Makarova, ...
Journal of Biological Chemistry 283 (29), 20361-20371, 2008
2662008
Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo
Y Liu, S Tan, L Huang, RB Abramovitch, KH Rohde, MD Zimmerman, ...
Journal of Experimental Medicine 213 (5), 809-825, 2016
1832016
Tuberculosis drugs’ distribution and emergence of resistance in patient’s lung lesions: a mechanistic model and tool for regimen and dose optimization
N Strydom, SV Gupta, WS Fox, LE Via, H Bang, M Lee, S Eum, TS Shim, ...
PLoS medicine 16 (4), e1002773, 2019
1572019
Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in Mycobacterium tuberculosis Infected C3HeB/FeJ Mice
SM Irwin, B Prideaux, ER Lyon, MD Zimmerman, EJ Brooks, CA Schrupp, ...
ACS infectious diseases 2 (4), 251-267, 2016
1262016
A naturally inspired antibiotic to target multidrug-resistant pathogens
Z Wang, B Koirala, Y Hernandez, M Zimmerman, S Park, DS Perlin, ...
Nature 601 (7894), 606-611, 2022
1142022
A public database of macromolecular diffraction experiments
M Grabowski, KM Langner, M Cymborowski, PJ Porebski, P Sroka, ...
Acta Crystallographica Section D: Structural Biology 72 (11), 1181-1193, 2016
1082016
Statin adjunctive therapy shortens the duration of TB treatment in mice
NK Dutta, N Bruiners, ML Pinn, MD Zimmerman, B Prideaux, V Dartois, ...
Journal of Antimicrobial Chemotherapy 71 (6), 1570-1577, 2016
1062016
X-ray crystallography over the past decade for novel drug discovery–where are we heading next?
H Zheng, KB Handing, MD Zimmerman, IG Shabalin, SC Almo, W Minor
Expert opinion on drug discovery 10 (9), 975-989, 2015
1052015
The future of crystallography in drug discovery
H Zheng, J Hou, MD Zimmerman, A Wlodawer, W Minor
Expert opinion on drug discovery 9 (2), 125-137, 2014
1052014
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development
T Beites, K O’Brien, D Tiwari, CA Engelhart, S Walters, J Andrews, ...
Nature communications 10 (1), 4970, 2019
932019
Structural insight into the mechanism of substrate specificity and catalytic activity of an HD-domain phosphohydrolase: the 5′-deoxyribonucleotidase YfbR from Escherichia coli
MD Zimmerman, M Proudfoot, A Yakunin, W Minor
Journal of molecular biology 378 (1), 215-226, 2008
872008
The Structural Biology Knowledgebase: a portal to protein structures, sequences, functions, and methods
MJ Gabanyi, PD Adams, K Arnold, L Bordoli, LG Carter, ...
Journal of structural and functional genomics 12, 45-54, 2011
822011
Host-mediated bioactivation of pyrazinamide: implications for efficacy, resistance, and therapeutic alternatives
LE Via, R Savic, DM Weiner, MD Zimmerman, B Prideaux, SM Irwin, ...
ACS infectious diseases 1 (5), 203-214, 2015
812015
Ethambutol partitioning in tuberculous pulmonary lesions explains its clinical efficacy
M Zimmerman, J Lestner, B Prideaux, P O'Brien, I Dias-Freedman, ...
Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00924-17, 2017
772017
Mass spectrometry imaging of levofloxacin distribution in TB-infected pulmonary lesions by MALDI-MSI and continuous liquid microjunction surface sampling
B Prideaux, MS ElNaggar, M Zimmerman, JM Wiseman, X Li, V Dartois
International journal of mass spectrometry 377, 699-708, 2015
752015
Analysis of solvent content and oligomeric states in protein crystals—does symmetry matter?
M Chruszcz, W Potrzebowski, MD Zimmerman, M Grabowski, H Zheng, ...
Protein Science 17 (4), 623-632, 2008
742008
Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in Mycobacterium tuberculosis
DA Negatu, Y Yamada, Y Xi, ML Go, M Zimmerman, U Ganapathy, ...
MBio 10 (2), 10.1128/mbio. 02781-18, 2019
712019
Whole-cell screen of fragment library identifies gut microbiota metabolite indole propionic acid as antitubercular
DA Negatu, JJJ Liu, M Zimmerman, F Kaya, V Dartois, CC Aldrich, ...
Antimicrobial agents and chemotherapy 62 (3), 10.1128/aac. 01571-17, 2018
702018
The system can't perform the operation now. Try again later.
Articles 1–20