Matthew David Zimmerman
Matthew David Zimmerman
Instructor
Verified email at iwonka.med.virginia.edu - Homepage
Title
Cited by
Cited by
Year
Structural and immunologic characterization of bovine, horse, and rabbit serum albumins
KA Majorek, PJ Porebski, A Dayal, MD Zimmerman, K Jablonska, ...
Molecular immunology 52 (3-4), 174-182, 2012
7432012
The association between sterilizing activity and drug distribution into tuberculosis lesions
B Prideaux, LE Via, MD Zimmerman, S Eum, J Sarathy, P O'brien, C Chen, ...
Nature medicine 21 (10), 1223-1227, 2015
3472015
A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats
N Beloglazova, G Brown, MD Zimmerman, M Proudfoot, KS Makarova, ...
Journal of Biological Chemistry 283 (29), 20361-20371, 2008
2352008
Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo
Y Liu, S Tan, L Huang, RB Abramovitch, KH Rohde, MD Zimmerman, ...
Journal of Experimental Medicine 213 (5), 809-825, 2016
1112016
Tuberculosis drugs’ distribution and emergence of resistance in patient’s lung lesions: a mechanistic model and tool for regimen and dose optimization
N Strydom, SV Gupta, WS Fox, LE Via, H Bang, M Lee, S Eum, TS Shim, ...
PLoS medicine 16 (4), e1002773, 2019
792019
A public database of macromolecular diffraction experiments
M Grabowski, KM Langner, M Cymborowski, PJ Porebski, P Sroka, ...
Acta Crystallographica Section D: Structural Biology 72 (11), 1181-1193, 2016
772016
Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in Mycobacterium tuberculosis Infected C3HeB/FeJ Mice
SM Irwin, B Prideaux, ER Lyon, MD Zimmerman, EJ Brooks, CA Schrupp, ...
ACS infectious diseases 2 (4), 251-267, 2016
762016
The Structural Biology Knowledgebase: a portal to protein structures, sequences, functions, and methods
MJ Gabanyi, PD Adams, K Arnold, L Bordoli, LG Carter, ...
Journal of structural and functional genomics 12 (2), 45-54, 2011
742011
Structural insight into the mechanism of substrate specificity and catalytic activity of an HD-domain phosphohydrolase: the 5′-deoxyribonucleotidase YfbR from Escherichia coli
MD Zimmerman, M Proudfoot, A Yakunin, W Minor
Journal of molecular biology 378 (1), 215-226, 2008
742008
Statin adjunctive therapy shortens the duration of TB treatment in mice
NK Dutta, N Bruiners, ML Pinn, MD Zimmerman, B Prideaux, V Dartois, ...
Journal of Antimicrobial Chemotherapy 71 (6), 1570-1577, 2016
732016
Host-mediated bioactivation of pyrazinamide: implications for efficacy, resistance, and therapeutic alternatives
LE Via, R Savic, DM Weiner, MD Zimmerman, B Prideaux, SM Irwin, ...
ACS infectious diseases 1 (5), 203-214, 2015
682015
The future of crystallography in drug discovery
H Zheng, J Hou, MD Zimmerman, A Wlodawer, W Minor
Expert opinion on drug discovery 9 (2), 125-137, 2014
672014
X-ray crystallography over the past decade for novel drug discovery–where are we heading next?
H Zheng, KB Handing, MD Zimmerman, IG Shabalin, SC Almo, W Minor
Expert opinion on drug discovery 10 (9), 975-989, 2015
582015
The impact of structural genomics: the first quindecennial
M Grabowski, E Niedzialkowska, MD Zimmerman, W Minor
Journal of structural and functional genomics 17 (1), 1-16, 2016
572016
Mass spectrometry imaging of levofloxacin distribution in TB-infected pulmonary lesions by MALDI-MSI and continuous liquid microjunction surface sampling
B Prideaux, MS ElNaggar, M Zimmerman, JM Wiseman, X Li, V Dartois
International journal of mass spectrometry 377, 699-708, 2015
572015
Analysis of solvent content and oligomeric states in protein crystals—does symmetry matter?
M Chruszcz, W Potrzebowski, MD Zimmerman, M Grabowski, H Zheng, ...
Protein Science 17 (4), 623-632, 2008
552008
Ethambutol partitioning in tuberculous pulmonary lesions explains its clinical efficacy
M Zimmerman, J Lestner, B Prideaux, P O'Brien, I Dias-Freedman, ...
Antimicrobial agents and chemotherapy 61 (9), e00924-17, 2017
462017
A sterilizing tuberculosis treatment regimen is associated with faster clearance of bacteria in cavitary lesions in marmosets
LE Via, K England, DM Weiner, D Schimel, MD Zimmerman, E Dayao, ...
Antimicrobial agents and chemotherapy 59 (7), 4181-4189, 2015
452015
A modern in vivo pharmacokinetic paradigm: combining snapshot, rapid and full PK approaches to optimize and expedite early drug discovery
C Li, B Liu, J Chang, T Groessl, M Zimmerman, YQ He, J Isbell, T Tuntland
Drug Discovery Today 18 (1-2), 71-78, 2013
452013
Whole-cell screen of fragment library identifies gut microbiota metabolite indole propionic acid as antitubercular
DA Negatu, JJJ Liu, M Zimmerman, F Kaya, V Dartois, CC Aldrich, ...
Antimicrobial agents and chemotherapy 62 (3), e01571-17, 2018
402018
The system can't perform the operation now. Try again later.
Articles 1–20