| Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6 C Vance, B Rogelj, T Hortobágyi, KJ De Vos, AL Nishimura, J Sreedharan, ... Science 323 (5918), 1208-1211, 2009 | 2964 | 2009 |
| Role of axonal transport in neurodegenerative diseases KJ De Vos, AJ Grierson, S Ackerley, CCJ Miller Annu. Rev. Neurosci. 31, 151-173, 2008 | 866 | 2008 |
| Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity. V Goossens, J Grooten, K De Vos, W Fiers Proceedings of the National Academy of Sciences 92 (18), 8115-8119, 1995 | 748 | 1995 |
| ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43 R Stoica, KJ De Vos, S Paillusson, S Mueller, RM Sancho, KF Lau, ... Nature communications 5 (1), 3996, 2014 | 583 | 2014 |
| VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis KJ De Vos, GM Morotz, R Stoica, EL Tudor, KF Lau, S Ackerley, A Warley, ... Human molecular genetics 21 (6), 1299-1311, 2012 | 499 | 2012 |
| Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content KJ De Vos, AL Chapman, ME Tennant, C Manser, EL Tudor, KF Lau, ... Human molecular genetics 16 (22), 2720-2728, 2007 | 484 | 2007 |
| The role of mitochondria in amyotrophic lateral sclerosis EF Smith, PJ Shaw, KJ De Vos Neuroscience letters 710, 132933, 2019 | 480 | 2019 |
| The C9orf72 protein interacts with Rab1a and the ULK 1 complex to regulate initiation of autophagy CP Webster, EF Smith, CS Bauer, A Moller, GM Hautbergue, L Ferraiuolo, ... The EMBO journal 35 (15), 1656-1676, 2016 | 422 | 2016 |
| Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity K Vancompernolle, F Van Herreweghe, G Pynaert, M Van de Craen, ... FEBS letters 438 (3), 150-158, 1998 | 392 | 1998 |
| Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission KJ De Vos, VJ Allan, AJ Grierson, MP Sheetz Current Biology 15 (7), 678-683, 2005 | 386 | 2005 |
| Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations VK Godena, N Brookes-Hocking, A Moller, G Shaw, M Oswald, ... Nature communications 5 (1), 5245, 2014 | 287 | 2014 |
| RPTP-α acts as a transducer of mechanical force on αv/β3-integrin–cytoskeleton linkages G Von Wichert, G Jiang, A Kostic, K De Vos, J Sap, MP Sheetz The Journal of cell biology 161 (1), 143-153, 2003 | 263 | 2003 |
| ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP 51 interaction and ER–mitochondria associations R Stoica, S Paillusson, P Gomez‐Suaga, JC Mitchell, DHW Lau, EH Gray, ... EMBO reports 17 (9), 1326-1342, 2016 | 250 | 2016 |
| Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research? KJ De Vos, M Hafezparast Neurobiology of disease 105, 283-299, 2017 | 234 | 2017 |
| The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region K De Vos, V Goossens, E Boone, D Vercammen, K Vancompernolle, ... Journal of Biological Chemistry 273 (16), 9673-9680, 1998 | 201 | 1998 |
| C9orf72 expansion disrupts ATM-mediated chromosomal break repair C Walker, S Herranz-Martin, E Karyka, C Liao, K Lewis, W Elsayed, ... Nature neuroscience 20 (9), 1225-1235, 2017 | 172 | 2017 |
| Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration TM Woodruff, JW Crane, LM Proctor, KM Buller, AB Shek, K De Vos, ... The FASEB Journal 20 (9), 1407-1417, 2006 | 160 | 2006 |
| Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria GM Morotz, KJ De Vos, A Vagnoni, S Ackerley, CE Shaw, CCJ Miller Human molecular genetics 21 (9), 1979-1988, 2012 | 153 | 2012 |
| Direct evidence for axonal transport defects in a novel mouse model of mutant spastin‐induced hereditary spastic paraplegia (HSP) and human HSP patients PR Kasher, KJ De Vos, SB Wharton, C Manser, EJ Bennett, M Bingley, ... Journal of neurochemistry 110 (1), 34-44, 2009 | 148 | 2009 |
| Tumor necrosis factor induces hyperphosphorylation of kinesin light chain and inhibits kinesin-mediated transport of mitochondria K De Vos, F Severin, F Van Herreweghe, K Vancompernolle, V Goossens, ... The Journal of cell biology 149 (6), 1207-1214, 2000 | 145 | 2000 |
