Arthur Christopoulos
Arthur Christopoulos
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Cited by
Cited by
Fitting models to biological data using linear and nonlinear regression: a practical guide to curve fitting
AC Harvey Motulsky
Oxford University Press, 2004
Functional selectivity and classical concepts of quantitative pharmacology
JD Urban, WP Clarke, M Von Zastrow, DE Nichols, B Kobilka, H Weinstein, ...
Journal of Pharmacology and Experimental Therapeutics 320 (1), 1-13, 2007
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
P Jeffrey Conn, A Christopoulos, CW Lindsley
Nature reviews Drug discovery 8 (1), 41-54, 2009
G protein-coupled receptor allosterism and complexing
A Christopoulos, T Kenakin
Pharmacological reviews 54 (2), 323-374, 2002
Activation and allosteric modulation of a muscarinic acetylcholine receptor
AC Kruse, AM Ring, A Manglik, J Hu, K Hu, K Eitel, H Hübner, E Pardon, ...
Nature 504 (7478), 101-106, 2013
Allosteric binding sites on cell-surface receptors: novel targets for drug discovery
A Christopoulos
Nature reviews Drug discovery 1 (3), 198-210, 2002
International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on terms and symbols in quantitative pharmacology
RR Neubig, M Spedding, T Kenakin, A Christopoulos
Pharmacological reviews 55 (4), 597-606, 2003
Signalling bias in new drug discovery: detection, quantification and therapeutic impact
T Kenakin, A Christopoulos
Nature reviews Drug discovery 12 (3), 205-216, 2013
Allosteric modulation of G protein–coupled receptors
LT May, K Leach, PM Sexton, A Christopoulos
Annu. Rev. Pharmacol. Toxicol. 47, 1-51, 2007
The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 176, S21-S141, 2019
The Concise Guide to PHARMACOLOGY 2017/18: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, NV Marrion, ...
British journal of pharmacology 174, S17-S129, 2017
Mechanisms of signalling and biased agonism in G protein-coupled receptors
D Wootten, A Christopoulos, M Marti-Solano, MM Babu, PM Sexton
Nature reviews Molecular cell biology 19 (10), 638-653, 2018
G-protein–coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor
E Kostenis, G Milligan, A Christopoulos, CF Sanchez-Ferrer, ...
Circulation 111 (14), 1806-1813, 2005
Emerging paradigms in GPCR allostery: implications for drug discovery
D Wootten, A Christopoulos, PM Sexton
Nature reviews Drug discovery 12 (8), 630-644, 2013
Allosteric modulation of the cannabinoid CB1 receptor
MR Price, GL Baillie, A Thomas, LA Stevenson, M Easson, R Goodwin, ...
Molecular pharmacology 68 (5), 1484-1495, 2005
Phase-plate cryo-EM structure of a class B GPCR–G-protein complex
YL Liang, M Khoshouei, M Radjainia, Y Zhang, A Glukhova, J Tarrasch, ...
Nature 546 (7656), 118-123, 2017
A simple method for quantifying functional selectivity and agonist bias
T Kenakin, C Watson, V Muniz-Medina, A Christopoulos, S Novick
ACS chemical neuroscience 3 (3), 193-203, 2012
The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 178, S27-S156, 2021
Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs
RO Dror, HF Green, C Valant, DW Borhani, JR Valcourt, AC Pan, ...
Nature 503 (7475), 295-299, 2013
Muscarinic acetylcholine receptors: novel opportunities for drug development
AC Kruse, BK Kobilka, D Gautam, PM Sexton, A Christopoulos, J Wess
Nature reviews Drug discovery 13 (7), 549-560, 2014
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