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Derek F Ceccarelli
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Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients
B Isho, KT Abe, M Zuo, AJ Jamal, B Rathod, JH Wang, Z Li, G Chao, ...
Science immunology 5 (52), eabe5511, 2020
7912020
Structural basis for the autoinhibition of focal adhesion kinase
D Lietha, X Cai, DFJ Ceccarelli, Y Li, MD Schaller, MJ Eck
Cell 129 (6), 1177-1187, 2007
5182007
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis
E Rivkin, SM Almeida, DF Ceccarelli, YC Juang, TA MacLean, T Srikumar, ...
Nature 498 (7454), 318-324, 2013
2812013
Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination
X Tang, S Orlicky, Z Lin, A Willems, D Neculai, D Ceccarelli, F Mercurio, ...
Cell 129 (6), 1165-1176, 2007
2502007
An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme
DF Ceccarelli, X Tang, B Pelletier, S Orlicky, W Xie, V Plantevin, ...
Cell 145 (7), 1075-1087, 2011
2482011
EBP2, a human protein that interacts with sequences of the Epstein-Barr virus nuclear antigen 1 important for plasmid maintenance
K Shire, DFJ Ceccarelli, TM Avolio-Hunter, L Frappier
Journal of virology 73 (4), 2587-2595, 1999
2131999
Spatial and temporal regulation of focal adhesion kinase activity in living cells
X Cai, D Lietha, DF Ceccarelli, AV Karginov, Z Rajfur, K Jacobson, ...
Molecular and cellular biology, 2008
2072008
OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function
YC Juang, MC Landry, M Sanches, V Vittal, CCY Leung, DF Ceccarelli, ...
Molecular cell 45 (3), 384-397, 2012
2052012
Crystal structure of the FERM domain of focal adhesion kinase
DFJ Ceccarelli, HK Song, F Poy, MD Schaller, MJ Eck
Journal of Biological Chemistry 281 (1), 252-259, 2006
1632006
Structure-function analysis of core STRIPAK Proteins: a signaling complex implicated in Golgi polarization
MJ Kean, DF Ceccarelli, M Goudreault, M Sanches, S Tate, B Larsen, ...
Journal of Biological Chemistry 286 (28), 25065-25075, 2011
1602011
FERM domain interaction promotes FAK signaling
JM Dunty, V Gabarra-Niecko, ML King, DFJ Ceccarelli, MJ Eck, ...
Molecular and cellular biology 24 (12), 5353-5368, 2004
1562004
Cleavage furrow organization requires PIP2-mediated recruitment of anillin
J Liu, GD Fairn, DF Ceccarelli, F Sicheri, A Wilde
Current biology 22 (1), 64-69, 2012
1402012
Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity
H Huang, E Zeqiraj, B Dong, BK Jha, NM Duffy, S Orlicky, ...
Molecular cell 53 (2), 221-234, 2014
1332014
Non-canonical interaction of phosphoinositides with pleckstrin homology domains of Tiam1 and ArhGAP9
DFJ Ceccarelli, IM Blasutig, M Goudreault, Z Li, J Ruston, T Pawson, ...
Journal of biological chemistry 282 (18), 13864-13874, 2007
1122007
The DNA segregation mechanism of Epstein–Barr virus nuclear antigen 1
H Wu, DFJ Ceccarelli, L Frappier
EMBO reports, 2000
1102000
Functional analyses of the EBNA1 origin DNA binding protein of Epstein-Barr virus
DFJ Ceccarelli, L Frappier
Journal of Virology 74 (11), 4939-4948, 2000
1102000
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine
DYL Mao, D Neculai, M Downey, S Orlicky, YZ Haffani, DF Ceccarelli, ...
Molecular cell 32 (2), 259-275, 2008
1072008
Dissecting BAR domain function in the yeast Amphiphysins Rvs161 and Rvs167 during endocytosis
JY Youn, H Friesen, T Kishimoto, WM Henne, CF Kurat, W Ye, ...
Molecular biology of the cell 21 (17), 3054-3069, 2010
932010
Functional characterization of a PROTAC directed against BRAF mutant V600E
G Posternak, X Tang, P Maisonneuve, T Jin, H Lavoie, S Daou, S Orlicky, ...
Nature chemical biology 16 (11), 1170-1178, 2020
922020
E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin
H Huang, DF Ceccarelli, S Orlicky, DJ St-Cyr, A Ziemba, P Garg, ...
Nature chemical biology 10 (2), 156-163, 2014
912014
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