TGF-β1 induces efficient differentiation of human cardiomyocyte progenitor cells into functional cardiomyocytes in vitro MJ Goumans, TP de Boer, AM Smits, LW van Laake, P van Vliet, ... Stem cell research 1 (2), 138-149, 2008 | 292 | 2008 |
The immature electrophysiological phenotype of iPSC-CMs still hampers in vitro drug screening: Special focus on IK1 B Goversen, MAG van der Heyden, TAB van Veen, TP de Boer Pharmacology & therapeutics 183, 127-136, 2018 | 169 | 2018 |
Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG MKB Jonsson, MA Vos, GR Mirams, G Duker, P Sartipy, TP De Boer, ... Journal of molecular and cellular cardiology 52 (5), 998-1008, 2012 | 166 | 2012 |
Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models? RH Johnstone, ETY Chang, R Bardenet, TP De Boer, DJ Gavaghan, ... Journal of molecular and cellular cardiology 96, 49-62, 2016 | 165 | 2016 |
High-throughput approaches for screening and analysis of cell behaviors J Seo, JY Shin, J Leijten, O Jeon, G Camci-Unal, AD Dikina, K Brinegar, ... Biomaterials 153, 85-101, 2018 | 85 | 2018 |
The mammalian KIR2.x inward rectifier ion channel family: expression pattern and pathophysiology TP De Boer, MJC Houtman, M Compier, MAG Van der Heyden Acta physiologica 199 (3), 243-256, 2010 | 81 | 2010 |
GNB5 mutations cause an autosomal-recessive multisystem syndrome with sinus bradycardia and cognitive disability EM Lodder, P De Nittis, CD Koopman, W Wiszniewski, CFM de Souza, ... The American Journal of Human Genetics 99 (3), 704-710, 2016 | 74 | 2016 |
Comparison of the IKr blockers moxifloxacin, dofetilide and E‐4031 in five screening models of pro‐arrhythmia reveals lack of specificity of isolated cardiomyocytes L Nalos, R Varkevisser, MKB Jonsson, MJC Houtman, JD Beekman, ... British journal of pharmacology 165 (2), 467-478, 2012 | 74 | 2012 |
Sensing cardiac electrical activity with a cardiac myocyte–targeted optogenetic voltage indicator ML Chang Liao, TP de Boer, H Mutoh, N Raad, C Richter, E Wagner, ... Circulation research 117 (5), 401-412, 2015 | 73 | 2015 |
Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics KA Beattie, AP Hill, R Bardenet, Y Cui, JI Vandenberg, DJ Gavaghan, ... Biophysical Journal 114 (3), 293a-294a, 2018 | 70 | 2018 |
Hyperpolarization induces differentiation in human cardiomyocyte progenitor cells P van Vliet, TP de Boer, MAG van der Heyden, MK El Tamer, JPG Sluijter, ... Stem cell reviews and reports 6, 178-185, 2010 | 61 | 2010 |
Perpetuation of torsade de pointes in heterogeneous hearts: competing foci or re‐entry? N Vandersickel, TP de Boer, MA Vos, AV Panfilov The Journal of physiology 594 (23), 6865-6878, 2016 | 59 | 2016 |
Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments CL Lei, M Clerx, DG Whittaker, DJ Gavaghan, TP de Boer, GR Mirams Philosophical Transactions of the Royal Society A 378 (2173), 20190348, 2020 | 57 | 2020 |
A hybrid model for safety pharmacology on an automated patch clamp platform: Using dynamic clamp to join iPSC-derived cardiomyocytes and simulations of Ik1 ion channels in real … B Goversen, N Becker, S Stoelzle-Feix, A Obergrussberger, MA Vos, ... Frontiers in Physiology 8, 1094, 2018 | 54 | 2018 |
A P19Cl6 GFP reporter line to quantify cardiomyocyte differentiation of stem cells. JC Moore, R Spijker, AC Martens, T de Boer, MB Rook, ... The International Journal of Developmental Biology 48 (1), 47-55, 2004 | 53 | 2004 |
Lysosome mediated Kir2. 1 breakdown directly influences inward rectifier current density JA Jansen, TP de Boer, R Wolswinkel, TAB van Veen, MA Vos, ... Biochemical and biophysical research communications 367 (3), 687-692, 2008 | 52 | 2008 |
Optogenetic sensors in the zebrafish heart: a novel in vivo electrophysiological tool to study cardiac arrhythmogenesis CJM van Opbergen, CD Koopman, BJM Kok, T Knöpfel, SL Renninger, ... Theranostics 8 (17), 4750, 2018 | 50 | 2018 |
Myocardial tissue slices: organotypic pseudo-2D models for cardiac research & development TP De Boer, P Camelliti, U Ravens, P Kohl Future cardiology 5 (5), 425-430, 2009 | 50 | 2009 |
Connexin43 repression following epithelium-to-mesenchyme transition in embryonal carcinoma cells requires Snail1 transcription factor TP De Boer, TAB Van Veen, MFA Bierhuizen, B Kok, MB Rook, ... Differentiation 75 (3), 208-218, 2007 | 50 | 2007 |
The anti‐protozoal drug pentamidine blocks KIR2.x‐mediated inward rectifier current by entering the cytoplasmic pore region of the channel TP De Boer, L Nalos, A Stary, B Kok, MJC Houtman, G Antoons, ... British journal of pharmacology 159 (7), 1532-1541, 2010 | 49 | 2010 |