| Mechanisms that regulate production of reactive oxygen species by cytochrome P450 RC Zangar, DR Davydov, S Verma Toxicology and applied pharmacology 199 (3), 316-331, 2004 | 689 | 2004 |
| Allosteric P450 mechanisms: multiple binding sites, multiple conformers or both? DR Davydov, JR Halpert Expert opinion on drug metabolism & toxicology 4 (12), 1523-1535, 2008 | 138 | 2008 |
| High-pressure-induced transitions in microsomal cytochrome P450 2B4 in solution: evidence for conformational inhomogeneity in the oligomers DR Davydov, E Deprez, GHB Hoa, TV Knyushko, GP Kuznetsova, ... Archives of biochemistry and biophysics 320 (2), 330-344, 1995 | 119 | 1995 |
| Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: heterogeneity of the enzyme caused by its oligomerization DR Davydov, H Fernando, BJ Baas, SG Sligar, JR Halpert Biochemistry 44 (42), 13902-13913, 2005 | 113 | 2005 |
| Microsomal monooxygenase in apoptosis: another target for cytochrome c signaling? DR Davydov Trends in biochemical sciences 26 (3), 155-160, 2001 | 107 | 2001 |
| Conformational heterogeneity of cytochrome P450 3A4 revealed by high pressure spectroscopy DR Davydov, JR Halpert, JP Renaud, GHB Hoa Biochemical and biophysical research communications 312 (1), 121-130, 2003 | 86 | 2003 |
| Microsomal monooxygenase as a multienzyme system: the role of P450-P450 interactions DR Davydov Expert opinion on drug metabolism & toxicology 7 (5), 543-558, 2011 | 84 | 2011 |
| Peripheral ligand-binding site in cytochrome P450 3A4 located with fluorescence resonance energy transfer (FRET) DR Davydov, JAO Rumfeldt, EV Sineva, H Fernando, NY Davydova, ... Journal of Biological Chemistry 287 (9), 6797-6809, 2012 | 74 | 2012 |
| Mechanism of interactions of α-naphthoflavone with cytochrome P450 3A4 explored with an engineered enzyme bearing a fluorescent probe TN Tsalkova, NY Davydova, JR Halpert, DR Davydov Biochemistry 46 (1), 106-119, 2007 | 73 | 2007 |
| Interactions among cytochromes P450 in microsomal membranes: oligomerization of cytochromes P450 3A4, 3A5, and 2E1 and its functional consequences DR Davydov, NY Davydova, EV Sineva, JR Halpert Journal of Biological Chemistry 290 (6), 3850-3864, 2015 | 70 | 2015 |
| Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of alpha-Naphthoflavone DR Davydov, Y Davydova, Nadezhda, V Sineva, Elena, I Kufareva, ... Biochemical Journal, 2013 | 67 | 2013 |
| Resolution of multiple substrate binding sites in cytochrome P450 3A4: the stoichiometry of the enzyme− substrate complexes probed by FRET and job's titration H Fernando, JR Halpert, DR Davydov Biochemistry 45 (13), 4199-4209, 2006 | 66 | 2006 |
| Association of cytochromes P450 with their reductases: opposite sign of the electrostatic interactions in P450BM-3 as compared with the microsomal 2B4 system DR Davydov, AA Kariakin, NA Petushkova, JA Peterson Biochemistry 39 (21), 6489-6497, 2000 | 64 | 2000 |
| Thermodynamic studies of substrate binding and spin transitions in human cytochrome P-450 3A4 expressed in yeast microsomes JP RENAUD, DR DAVYDOV, KPM HEIRWEGH, D MANSUY, ... Biochemical Journal 319 (3), 675-681, 1996 | 61 | 1996 |
| Dynamics of protein-bound water in the heme domain of P450BM3 studied by high-pressure spectroscopy: Comparison with P450cam and P450 2B4 DR Davydov, G Hui Bon Hoa, JA Peterson Biochemistry 38 (2), 751-761, 1999 | 58 | 1999 |
| Electron transfer in the complex of membrane-bound human cytochrome P450 3A4 with the flavin domain of P450BM-3: the effect of oligomerization of the heme protein and … DR Davydov, EV Sineva, S Sistla, NY Davydova, DJ Frank, SG Sligar, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1797 (3), 378-390, 2010 | 57 | 2010 |
| Concurrent cooperativity and substrate inhibition in the epoxidation of carbamazepine by cytochrome P450 3A4 active site mutants inspired by molecular dynamics simulations CS Müller, T Knehans, DR Davydov, PL Bounds, U von Mandach, ... Biochemistry 54 (3), 711-721, 2015 | 48 | 2015 |
| Allosteric mechanisms in cytochrome P450 3A4 studied by high-pressure spectroscopy: pivotal role of substrate-induced changes in the accessibility and degree of hydration of … DR Davydov, BJ Baas, SG Sligar, JR Halpert Biochemistry 46 (26), 7852-7864, 2007 | 48 | 2007 |
| Role of cytochrome B5 in modulating peroxide-supported cyp3a4 activity: evidence for a conformational transition and cytochrome P450 heterogeneity S Kumar, DR Davydov, JR Halpert Drug metabolism and disposition 33 (8), 1131-1136, 2005 | 46 | 2005 |
| Structure and Function of the Cytochrome P450 Monooxygenase Cinnamate 4-hydroxylase from Sorghum bicolor B Zhang, KM Lewis, A Abril, DR Davydov, W Vermerris, SE Sattler, ... Plant physiology 183 (3), 957-973, 2020 | 45 | 2020 |
