Caenorhabditis elegans dnj-14, the orthologue of the DNAJC5 gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for … SS Kashyap, JR Johnson, HV McCue, X Chen, MJ Edmonds, M Ayala, ... Human molecular genetics 23 (22), 5916-5927, 2014 | 49 | 2014 |
Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression X Chen, HV McCue, SQ Wong, SS Kashyap, BC Kraemer, JW Barclay, ... Molecular neurodegeneration 10 (1), 51, 2015 | 41 | 2015 |
Functional genomics in Brugia malayi reveal diverse muscle nAChRs and differences between cholinergic anthelmintics S Verma, SS Kashyap, AP Robertson, RJ Martin Proceedings of the National Academy of Sciences 114 (21), 5539-5544, 2017 | 39 | 2017 |
Emodepside has sex-dependent immobilizing effects on adult Brugia malayi due to a differentially spliced binding pocket in the RCK1 region of the SLO-1 K channel SS Kashyap, S Verma, D Voronin, S Lustigman, D Kulke, AP Robertson, ... PLoS Pathogens 15 (9), e1008041, 2019 | 32 | 2019 |
Diethylcarbamazine activates TRP channels including TRP-2 in filaria, Brugia malayi S Verma, SS Kashyap, AP Robertson, RJ Martin Communications biology 3 (1), 398, 2020 | 21 | 2020 |
A MIG-15/JNK-1 MAP kinase cascade opposes RPM-1 signaling in synapse formation and learning O Crawley, AC Giles, M Desbois, S Kashyap, R Birnbaum, B Grill PLoS genetics 13 (12), e1007095, 2017 | 21 | 2017 |
Advances in our understanding of nematode ion channels as potential anthelmintic targets S Choudhary, SS Kashyap, RJ Martin, AP Robertson International Journal for Parasitology: Drugs and Drug Resistance 18, 52-86, 2022 | 15 | 2022 |
Anthelmintic resistance and homeostatic plasticity (Brugia malayi) SS Kashyap, S Verma, M McHugh, M Wolday, PD Williams, AP Robertson, ... Scientific Reports 11 (1), 14499, 2021 | 9 | 2021 |
Rab-3 and unc-18 Interactions in Alcohol Sensitivity Are Distinct from Synaptic Transmission JR Johnson, S Kashyap, K Rankin, JW Barclay PloS one 8 (11), e81117, 2013 | 9 | 2013 |
Anthelmintics: the best way to predict the future is to create it RJ Martin, S Verma, S Choudhary, S Kashyap, M Abongwa, F Zheng, ... Veterinary Parasitology 212 (1-2), 18-24, 2015 | 5 | 2015 |
Diethylcarbamazine, TRP channels and Ca2+ signaling in cells of the Ascaris intestine PDE Williams, SS Kashyap, MA McHugh, MT Brewer, AP Robertson, ... Scientific Reports 12 (1), 21317, 2022 | 4 | 2022 |
Diethylcarbamazine elicits Ca2+ signals through TRP-2 channels that are potentiated by emodepside in Brugia malayi muscles PDE Williams, SS Kashyap, AP Robertson, RJ Martin Antimicrobial Agents and Chemotherapy 67 (10), e00419-23, 2023 | 2 | 2023 |
Diethylcarbamazine mediated potentiation of emodepside induced paralysis requires TRP-2 in adult Brugia malayi SS Kashyap, MA McHugh, AP Robertson, RJ Martin International Journal for Parasitology: Drugs and Drug Resistance 20, 108-112, 2022 | 2 | 2022 |
Nodulisporic acid produces direct activation and positive allosteric modulation of AVR-14B, a glutamate-gated chloride channel from adult Brugia malayi S Choudhary, M Abongwa, SS Kashyap, S Verma, GR Mair, D Kulke, ... Proceedings of the National Academy of Sciences 119 (34), e2111932119, 2022 | 2 | 2022 |
Author Correction: Diethylcarbamazine activates TRP channels including TRP-2 in filaria, Brugia malayi S Verma, SS Kashyap, AP Robertson, RJ Martin Communications Biology 3, 2020 | 2 | 2020 |
Getting around the roundworms: Identifying knowledge gaps and research priorities for the ascarids. AJ Wolstenholme, EC Andersen, S Choudhary, F Ebner, S Hartmann, ... Advances in Parasitology 123, 51-123, 2024 | | 2024 |
High concentrations of the anthelmintic diethylcarbamazine paralyze C. elegans independently of TRP-2 R Datta, A Robertson, R Martin, S Kashyap Micropublication Biology 2022, 2022 | | 2022 |
dnj-14: a new C. elegans model for neurodegenerative diseases S Kashyap University of Liverpool, 2013 | | 2013 |