| Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis S Yoshida, S Tsutsumi, G Muhlebach, C Sourbier, MJ Lee, S Lee, ... Proceedings of the National Academy of Sciences 110 (17), E1604-E1612, 2013 | 251 | 2013 |
| Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1α stabilization by glucose-dependent generation of … S Sudarshan, C Sourbier, HS Kong, K Block, VAV Romero, Y Yang, ... Molecular and cellular biology 29 (15), 4080-4090, 2009 | 244 | 2009 |
| The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels WH Tong, C Sourbier, G Kovtunovych, SY Jeong, M Vira, M Ghosh, ... Cancer cell 20 (3), 315-327, 2011 | 222 | 2011 |
| The phosphoinositide 3-kinase/Akt pathway: a new target in human renal cell carcinoma therapy C Sourbier, V Lindner, H Lang, A Agouni, E Schordan, S Danilin, ... Cancer research 66 (10), 5130-5142, 2006 | 207 | 2006 |
| UOK 262 cell line, fumarate hydratase deficient (FH−/FH−) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in … Y Yang, VA Valera, HM Padilla-Nash, C Sourbier, CD Vocke, MA Vira, ... Cancer genetics and cytogenetics 196 (1), 45-55, 2010 | 155 | 2010 |
| Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity S Khiati, I Dalla Rosa, C Sourbier, X Ma, VA Rao, LM Neckers, H Zhang, ... Clinical Cancer Research 20 (18), 4873-4881, 2014 | 131 | 2014 |
| Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism C Douarre, C Sourbier, I Dalla Rosa, B Brata Das, CE Redon, H Zhang, ... PloS one 7 (7), e41094, 2012 | 122 | 2012 |
| Metformin Targets Mitochondrial Glycerophosphate Dehydrogenase to Control Rate of Oxidative Phosphorylation and Growth of Thyroid Cancer In Vitro and In Vivo S Thakur, B Daley, K Gaskins, VV Vasko, M Boufraqech, D Patel, ... Clinical cancer research 24 (16), 4030-4043, 2018 | 119 | 2018 |
| New strategies in renal cell carcinoma: targeting the genetic and metabolic basis of disease R Srinivasan, CJ Ricketts, C Sourbier, WM Linehan Clinical cancer research 21 (1), 10-17, 2015 | 119 | 2015 |
| SDHB-deficient cancers: the role of mutations that impair iron sulfur cluster delivery N Saxena, N Maio, DR Crooks, CJ Ricketts, Y Yang, MH Wei, TWM Fan, ... Journal of the National Cancer Institute 108 (1), djv287, 2016 | 115 | 2016 |
| Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma Y Yang, AN Lane, CJ Ricketts, C Sourbier, MH Wei, B Shuch, L Pike, ... PLoS One 8 (8), e72179, 2013 | 108 | 2013 |
| Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer C Sourbier, CJ Ricketts, S Matsumoto, DR Crooks, PJ Liao, PZ Mannes, ... Cancer cell 26 (6), 840-850, 2014 | 106 | 2014 |
| Alternative splicing of the cell fate determinant Numb in hepatocellular carcinoma Y Lu, W Xu, J Ji, D Feng, C Sourbier, Y Yang, J Qu, Z Zeng, C Wang, ... Hepatology 62 (4), 1122-1131, 2015 | 96 | 2015 |
| Discovering targets of non-enzymatic acylation by thioester reactivity profiling RA Kulkarni, AJ Worth, TT Zengeya, JH Shrimp, JM Garlick, AM Roberts, ... Cell chemical biology 24 (2), 231-242, 2017 | 92 | 2017 |
| Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality C Sourbier, BT Scroggins, R Ratnayake, TL Prince, S Lee, MJ Lee, ... Cancer cell 23 (2), 228-237, 2013 | 92 | 2013 |
| Targeting the nuclear factor-κB rescue pathway has promising future in human renal cell carcinoma therapy C Sourbier, S Danilin, V Lindner, J Steger, S Rothhut, N Meyer, ... Cancer research 67 (24), 11668-11676, 2007 | 76 | 2007 |
| Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration S Khiati, SA Baechler, VM Factor, H Zhang, SN Huang, I Dalla Rosa, ... Proceedings of the National Academy of Sciences 112 (36), 11282-11287, 2015 | 65 | 2015 |
| Role of the RNA-binding protein HuR in human renal cell carcinoma S Danilin, C Sourbier, L Thomas, V Lindner, S Rothhut, V Dormoy, ... Carcinogenesis 31 (6), 1018-1026, 2010 | 64 | 2010 |
| The HSP90 inhibitor ganetespib synergizes with the MET kinase inhibitor crizotinib in both crizotinib-sensitive and-resistant MET-driven tumor models N Miyajima, S Tsutsumi, C Sourbier, K Beebe, M Mollapour, C Rivas, ... Cancer research 73 (23), 7022-7033, 2013 | 60 | 2013 |
| Parathyroid hormone-related protein in human renal cell carcinoma C Sourbier, T Massfelder Cancer letters 240 (2), 170-182, 2006 | 56 | 2006 |
