Artemisinins target the SERCA of Plasmodium falciparum U Eckstein-Ludwig, RJ Webb, IDA Van Goethem, JM East, AG Lee, ... Nature 424 (6951), 957-961, 2003 | 1349 | 2003 |
Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I I Petitpas, AA Bhattacharya, S Twine, M East, S Curry Journal of Biological Chemistry 276 (25), 22804-22809, 2001 | 920 | 2001 |
A single amino acid residue can determine the sensitivity of SERCAs to artemisinins AC Uhlemann, A Cameron, U Eckstein-Ludwig, J Fischbarg, P Iserovich, ... Nature structural & molecular biology 12 (7), 628-629, 2005 | 349 | 2005 |
Lipid selectivity of the calcium and magnesium ion dependent adenosine triphosphatase, studied with fluorescence quenching by a brominated phospholipid JM East, AG Lee Biochemistry 21 (17), 4144-4151, 1982 | 290 | 1982 |
The ability of fish oil to suppress tumor necrosis factor α production by peripheral blood mononuclear cells in healthy men is associated with polymorphisms in genes that … RF Grimble, WM Howell, G O’Reilly, SJ Turner, O Markovic, S Hirrell, ... The American journal of clinical nutrition 76 (2), 454-459, 2002 | 266 | 2002 |
Distribution of two distinct Ca2+ -ATPase-like proteins and their relationships to the agonist-sensitive calcium store in adrenal chromaff in cells RD Burgoyne, TR Cheek, A Morgan, AJ O'Sullivan, RB Moreton, ... Nature 342 (6245), 72-74, 1989 | 215 | 1989 |
A diversity of SERCA Ca2+ pump inhibitors F Michelangeli, JM East Biochemical Society Transactions 39 (3), 789-797, 2011 | 187 | 2011 |
Annular and non-annular binding sites on the (Ca2++ Mg2+)-ATPase AC Simmonds, JM East, OT Jones, EK Rooney, J McWhirter, AG Lee Biochimica et Biophysica Acta (BBA)-Biomembranes 693 (2), 398-406, 1982 | 187 | 1982 |
What the structure of a calcium pump tells us about its mechanism AG LEE, JM EAST Biochemical Journal 356 (3), 665-683, 2001 | 169 | 2001 |
Hydrophobic mismatch and the incorporation of peptides into lipid bilayers: a possible mechanism for retention in the Golgi RJ Webb, JM East, RP Sharma, AG Lee Biochemistry 37 (2), 673-679, 1998 | 169 | 1998 |
Binding of anionic lipids to at least three nonannular sites on the potassium channel KcsA is required for channel opening P Marius, M Zagnoni, ME Sandison, JM East, H Morgan, AG Lee Biophysical journal 94 (5), 1689-1698, 2008 | 164 | 2008 |
Sarcolipin uncouples hydrolysis of ATP from accumulation of Ca2+ by the Ca2+-ATPase of skeletal-muscle sarcoplasmic reticulum WS Smith, R Broadbridge, JM East, AG Lee Biochemical Journal 361 (2), 277-286, 2002 | 162 | 2002 |
Exchange rates and numbers of annular lipids for the calcium and magnesium ion dependent adenosine triphosphatase JM East, D Melville, AG Lee Biochemistry 24 (11), 2615-2623, 1985 | 144 | 1985 |
The conformation of pyrethroids bound to lipid bilayers F Michelangeli, MJ Robson, JM East, AG Lee Biochimica et biophysica acta (bba)-biomembranes 1028 (1), 49-57, 1990 | 136 | 1990 |
The presence of sarcolipin results in increased heat production by Ca2+-ATPase S Mall, R Broadbridge, SL Harrison, MG Gore, AG Lee, JM East Journal of Biological Chemistry 281 (48), 36597-36602, 2006 | 130 | 2006 |
Curcumin, a molecule that inhibits the Ca2+-ATPase of sarcoplasmic reticulum but increases the rate of accumulation of Ca2+ MJ Logan-Smith, PJ Lockyer, JM East, AG Lee Journal of Biological Chemistry 276 (50), 46905-46911, 2001 | 129 | 2001 |
Interactions of phospholipids with the potassium channel KcsA IM Williamson, SJ Alvis, JM East, AG Lee Biophysical Journal 83 (4), 2026-2038, 2002 | 122 | 2002 |
Expression and functional characterization of a Plasmodium falciparum Ca2+-ATPase (PfATP4) belonging to a subclass unique to apicomplexan organisms S Krishna, C Woodrow, R Webb, J Penny, K Takeyasu, M Kimura, JM East Journal of Biological Chemistry 276 (14), 10782-10787, 2001 | 120 | 2001 |
Sarco (endo) plasmic reticulum calcium pumps: recent advances in our understanding of structure/function and biology JM East Molecular membrane biology 17 (4), 189-200, 2000 | 120 | 2000 |
Lipid− protein interactions studied by introduction of a tryptophan residue: the mechanosensitive channel MscL AM Powl, JM East, AG Lee Biochemistry 42 (48), 14306-14317, 2003 | 117 | 2003 |