Chris Bakal
Chris Bakal
Team Leader, Chester Beatty Laboratories, Institute of Cancer Research
Verified email at icr.ac.uk
Title
Cited by
Cited by
Year
The MAGUK family protein CARD11 is essential for lymphocyte activation
H Hara, T Wada, C Bakal, I Kozieradzki, S Suzuki, N Suzuki, M Nghiem, ...
Immunity 18 (6), 763-775, 2003
3432003
Quantitative morphological signatures define local signaling networks regulating cell morphology
C Bakal, J Aach, G Church, N Perrimon
science 316 (5832), 1753-1756, 2007
2902007
Genomic screening with RNAi: results and challenges
S Mohr, C Bakal, N Perrimon
Annual review of biochemistry 79, 37-64, 2010
2802010
Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death
H Okada, C Bakal, A Shahinian, A Elia, A Wakeham, WK Suh, GS Duncan, ...
The Journal of experimental medicine 199 (3), 399-410, 2004
1472004
Phosphorylation networks regulating JNK activity in diverse genetic backgrounds
C Bakal, R Linding, F Llense, E Heffern, E Martin-Blanco, T Pawson, ...
science 322 (5900), 453-456, 2008
1362008
A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes
Z Yin, A Sadok, H Sailem, A McCarthy, X Xia, F Li, MA Garcia, L Evans, ...
Nature cell biology 15 (7), 860-871, 2013
1312013
DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression
AR Barr, S Cooper, FS Heldt, F Butera, H Stoy, J Mansfeld, B Novák, ...
Nature communications 8 (1), 1-17, 2017
1142017
Cell shape and the microenvironment regulate nuclear translocation of NF‐κB in breast epithelial and tumor cells
JE Sero, HZ Sailem, RC Ardy, H Almuttaqi, T Zhang, C Bakal
Molecular systems biology 11 (3), 790, 2015
1002015
Enhancing light absorption and charge transfer efficiency in carbon dots through graphitization and core nitrogen doping
BCM Martindale, GAM Hutton, CA Caputo, S Prantl, R Godin, JR Durrant, ...
Angewandte Chemie 129 (23), 6559-6563, 2017
982017
Single-cell dynamics determines response to CDK4/6 inhibition in triple-negative breast cancer
US Asghar, AR Barr, R Cutts, M Beaney, I Babina, D Sampath, J Giltnane, ...
Clinical cancer research 23 (18), 5561-5572, 2017
822017
Microenvironmental heterogeneity parallels breast cancer progression: a histology–genomic integration analysis
R Natrajan, H Sailem, FK Mardakheh, M Arias Garcia, CJ Tape, ...
PLoS medicine 13 (2), e1001961, 2016
732016
Mechanistic insight into the microtubule and actin cytoskeleton coupling through dynein-dependent RhoGEF inhibition
D Meiri, CB Marshall, MA Greeve, B Kim, M Balan, F Suarez, C Bakal, ...
Molecular cell 45 (5), 642-655, 2012
652012
The twin spot generator for differential Drosophila lineage analysis
R Griffin, A Sustar, M Bonvin, R Binari, A del Valle Rodriguez, AM Hohl, ...
Nature methods 6 (8), 600, 2009
592009
A dynamical framework for the all-or-none G1/S transition
AR Barr, FS Heldt, T Zhang, C Bakal, B Novák
Cell systems 2 (1), 27-37, 2016
582016
Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens
Z Yin, X Zhou, C Bakal, F Li, Y Sun, N Perrimon, STC Wong
BMC bioinformatics 9 (1), 264, 2008
502008
Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity
H Sailem, V Bousgouni, S Cooper, C Bakal
Open biology 4 (1), 130132, 2014
492014
Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning
JE Sero, CK Thodeti, A Mammoto, C Bakal, S Thomas, DE Ingber
PLoS One 6 (12), e28303, 2011
432011
Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis
L Stojic, ATL Lun, J Mangei, P Mascalchi, V Quarantotti, AR Barr, C Bakal, ...
Nucleic acids research 46 (12), 5950-5966, 2018
392018
Multiparametric analysis of cell shape demonstrates that β-PIX directly couples YAP activation to extracellular matrix adhesion
JE Sero, C Bakal
Cell systems 4 (1), 84-96. e6, 2017
292017
RNAiCut: automated detection of significant genes from functional genomic screens
IM Kaplow, R Singh, A Friedman, C Bakal, N Perrimon, B Berger
Nature methods 6 (7), 476-477, 2009
292009
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