Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells BZ Carter, DH Mak, WD Schober, T McQueen, D Harris, Z Estrov, ... Blood 108 (2), 630-637, 2006 | 250 | 2006 |
Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells M Daher, R Basar, E Gokdemir, N Baran, N Uprety, AK Nunez Cortes, ... Blood, The Journal of the American Society of Hematology 137 (5), 624-636, 2021 | 184 | 2021 |
In vivo antioxidant action of a lignan-enriched extract of Schisandra fruit and an anthraquinone-containing extract of Polygonum root in comparison with schisandrin B and emodin PY Chiu, DHF Mak, MKT Poon, KM Ko Planta medica 68 (11), 951-956, 2002 | 161 | 2002 |
Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells BZ Carter, PY Mak, H Mu, H Zhou, DH Mak, W Schober, JD Leverson, ... Science translational medicine 8 (355), 355ra117-355ra117, 2016 | 160 | 2016 |
MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex M Konopleva, M Milella, P Ruvolo, JC Watts, MR Ricciardi, B Korchin, ... Leukemia 26 (4), 778-787, 2012 | 158 | 2012 |
Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5 BZ Carter, DH Mak, WD Schober, MF Dietrich, C Pinilla, LT Vassilev, ... Blood, The Journal of the American Society of Hematology 111 (7), 3742-3750, 2008 | 158 | 2008 |
Alterations in tissue glutathione antioxidant system in streptozotocin-induced diabetic rats DHF Mak, SP Ip, PC Li, MKT Poon, KM Ko Molecular and cellular biochemistry 162, 153-158, 1996 | 152 | 1996 |
Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary … AD Schimmer, EH Estey, G Borthakur, BZ Carter, GJ Schiller, MS Tallman, ... Journal of Clinical Oncology 27 (28), 4741, 2009 | 137 | 2009 |
Regulation of survivin expression through Bcr-Abl/MAPK cascade: targeting survivin overcomes imatinib resistance and increases imatinib sensitivity in imatinib-responsive CML cells BZ Carter, DH Mak, WD Schober, M Cabreira-Hansen, M Beran, ... Blood 107 (4), 1555-1563, 2006 | 122 | 2006 |
Myocardial protection against ischaemia‐ reperfusion injury by a Polygonum multiflorum extract supplemented ‘Dang‐Gui decoction for enriching blood’, a compound … TK Yim, WK Wu, WF Pak, DHF Mak, SM Liang, KM Ko Phytotherapy Research 14 (3), 195-199, 2000 | 118 | 2000 |
Myocardial protective effect of an anthraquinone-containing extract of Polygonum multiflorum ex vivo TK Yim, WK Wu, DHF Mak, KM Ko Planta medica 64 (07), 607-611, 1998 | 116 | 1998 |
Survivin is highly expressed in CD34+38− leukemic stem/progenitor cells and predicts poor clinical outcomes in AML BZ Carter, Y Qiu, X Huang, L Diao, N Zhang, KR Coombes, DH Mak, ... Blood, The Journal of the American Society of Hematology 120 (1), 173-180, 2012 | 103 | 2012 |
Single‐cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3‐ITD‐mutated AML stem/progenitor cells L Han, P Qiu, Z Zeng, JL Jorgensen, DH Mak, JK Burks, W Schober, ... Cytometry Part A 87 (4), 346-356, 2015 | 99 | 2015 |
Hepatoprotective mechanism of schisandrin B: role of mitochondrial glutathione antioxidant status and heat shock proteins PY Chiu, MH Tang, DHF Mak, MKT Poon, KM Ko Free Radical Biology and Medicine 35 (4), 368-380, 2003 | 99 | 2003 |
Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models L Han, Q Zhang, M Dail, C Shi, A Cavazos, VR Ruvolo, Y Zhao, E Kim, ... Haematologica 105 (3), 697, 2020 | 98 | 2020 |
Combined inhibition of β-catenin and Bcr–Abl synergistically targets tyrosine kinase inhibitor-resistant blast crisis chronic myeloid leukemia blasts and progenitors in vitro … H Zhou, PY Mak, H Mu, DH Mak, Z Zeng, J Cortes, Q Liu, M Andreeff, ... Leukemia 31 (10), 2065-2074, 2017 | 91 | 2017 |
Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML BZ Carter, DH Mak, WD Schober, E Koller, C Pinilla, LT Vassilev, ... Blood, The Journal of the American Society of Hematology 115 (2), 306-314, 2010 | 87 | 2010 |
XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38− cells in a phase 1/2 study of patients … BZ Carter, DH Mak, SJ Morris, G Borthakur, E Estey, AL Byrd, ... Apoptosis 16, 67-74, 2011 | 83 | 2011 |
Targeting MCL-1 dysregulates cell metabolism and leukemia-stroma interactions and re-sensitizes acute myeloid leukemia to BCL-2 inhibition BZ Carter, PY Mak, W Tao, M Warmoes, PL Lorenzi, D Mak, V Ruvolo, ... Haematologica 107 (1), 58, 2022 | 82 | 2022 |
Effect of a Lignan‐Enriched Extract of Schisandra Chinensis on Aflatoxin B1 and Cadmium Chloride‐Induced Hepatotoxicity in Rats SP Ip, DHF Mak, PC Li, MKT Poon, KM Ko Pharmacology & toxicology 78 (6), 413-416, 1996 | 80 | 1996 |