| Genome analysis reveals insights into physiology and longevity of the Brandt’s bat Myotis brandtii I Seim, X Fang, Z Xiong, AV Lobanov, Z Huang, S Ma, Y Feng, ... Nature communications 4 (1), 1-8, 2013 | 268 | 2013 |
| Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes X Fang, I Seim, Z Huang, MV Gerashchenko, Z Xiong, AA Turanov, Y Zhu, ... Cell reports 8 (5), 1354-1364, 2014 | 155 | 2014 |
| Revised genomic structure of the human ghrelin gene and identification of novel exons, alternative splice variants and natural antisense transcripts I Seim, C Collet, AC Herington, LK Chopin BMC genomics 8 (1), 1-16, 2007 | 146 | 2007 |
| The ghrelin axis—does it have an appetite for cancer progression? LK Chopin, I Seim, CM Walpole, AC Herington Endocrine reviews 33 (6), 849-891, 2012 | 95 | 2012 |
| Ghrelin and cancer L Chopin, C Walpole, I Seim, P Cunningham, R Murray, E Whiteside, ... Molecular and cellular endocrinology 340 (1), 65-69, 2011 | 87 | 2011 |
| Population genomics of finless porpoises reveal an incipient cetacean species adapted to freshwater X Zhou, X Guang, D Sun, S Xu, M Li, I Seim, W Jie, L Yang, Q Zhu, J Xu, ... Nature communications 9 (1), 1-8, 2018 | 74 | 2018 |
| Irritable bowel syndrome: the role of gut neuroendocrine peptides M El-Salhy, I Seim, L Chopin, D Gundersen, JG Hatlebakk, T Hausken Frontiers in bioscience (Elite edition) 4 (8), 2683-2700, 2012 | 71 | 2012 |
| The expanding roles of the ghrelin-gene derived peptide obestatin in health and disease I Seim, C Walpole, L Amorim, P Josh, A Herington, L Chopin Molecular and cellular endocrinology 340 (1), 111-117, 2011 | 67 | 2011 |
| The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal I Seim, S Ma, X Zhou, MV Gerashchenko, SG Lee, R Suydam, JC George, ... Aging (Albany NY) 6 (10), 879, 2014 | 62 | 2014 |
| Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human SL MacRae, Q Zhang, C Lemetre, I Seim, RB Calder, J Hoeijmakers, ... Aging Cell 14 (2), 288-291, 2015 | 59 | 2015 |
| New insights into the molecular complexity of the ghrelin gene locus I Seim, AC Herington, LK Chopin Cytokine & growth factor reviews 20 (4), 297-304, 2009 | 56 | 2009 |
| Whole-genome sequence of the metastatic PC3 and LNCaP human prostate cancer cell lines I Seim, PL Jeffery, PB Thomas, CC Nelson, LK Chopin G3: Genes, Genomes, Genetics 7 (6), 1731-1741, 2017 | 47 | 2017 |
| Adaptive aneuploidy protects against thiol peroxidase deficiency by increasing respiration via key mitochondrial proteins A Kaya, MV Gerashchenko, I Seim, J Labarre, MB Toledano, ... Proceedings of the National Academy of Sciences 112 (34), 10685-10690, 2015 | 47 | 2015 |
| Ghrelin and the brain-gut axis as a pharmacological target for appetite control I Seim, M El-Salhy, T Hausken, D Gundersen, L Chopin Current pharmaceutical design 18 (6), 768-775, 2012 | 43 | 2012 |
| Ghrelin gene‐related peptides: Multifunctional endocrine/autocrine modulators in health and disease I Seim, L Amorim, C Walpole, S Carter, LK Chopin, AC Herington Clinical and Experimental Pharmacology and Physiology 37 (1), 125-131, 2010 | 43 | 2010 |
| Gene expression signatures of human cell and tissue longevity I Seim, S Ma, VN Gladyshev npj Aging and Mechanisms of Disease 2 (1), 1-8, 2016 | 39 | 2016 |
| A variant of the KLK4 gene is expressed as a cis sense–antisense chimeric transcript in prostate cancer cells J Lai, ML Lehman, ME Dinger, SC Hendy, TR Mercer, I Seim, ... Rna 16 (6), 1156-1166, 2010 | 39 | 2010 |
| Expression and in vitro functions of the ghrelin axis in endometrial cancer JNT Fung, I Seim, D Wang, A Obermair, LK Chopin, C Chen Hormones and Cancer 1 (5), 245-255, 2010 | 38 | 2010 |
| Ghrelin axis genes, peptides and receptors: recent findings and future challenges I Seim, P Josh, P Cunningham, A Herington, L Chopin Molecular and cellular endocrinology 340 (1), 3-9, 2011 | 37 | 2011 |
| Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitroby ghrelin I Seim, PL Jeffery, L De Amorim, CM Walpole, J Fung, EJ Whiteside, ... Reproductive Biology and Endocrinology 11 (1), 1-9, 2013 | 35 | 2013 |
Vadim GladyshevProfessor of Medicine, Brigham and Women's Hospital, Harvard Medical SchoolVerified email at rics.bwh.harvard.edu
