Adam L MacLean
TitleCited byYear
The ecology in the hematopoietic stem cell niche determines the clinical outcome in chronic myeloid leukemia
AL MacLean, S Filippi, MPH Stumpf
Proceedings of the National Academy of Sciences 111 (10), 3883-3888, 2014
392014
Parameter-free methods distinguish Wnt pathway models and guide design of experiments
AL MacLean, Z Rosen, HM Byrne, HA Harrington
Proceedings of the National Academy of Sciences 112 (9), 2652-2657, 2015
372015
Multiscale modeling of inflammation-induced tumorigenesis reveals competing oncogenic and oncoprotective roles for inflammation
Y Guo, Q Nie, AL MacLean, Y Li, J Lei, S Li
Cancer research 77 (22), 6429-6441, 2017
322017
Population dynamics of normal and leukaemia stem cells in the haematopoietic stem cell niche show distinct regimes where leukaemia will be controlled
AL MacLean, C Lo Celso, MPH Stumpf
Journal of The Royal Society Interface 10 (81), 20120968, 2013
262013
scEpath: energy landscape-based inference of transition probabilities and cellular trajectories from single-cell transcriptomic data
S Jin, AL MacLean, T Peng, Q Nie
Bioinformatics 34 (12), 2077-2086, 2018
212018
Exploring intermediate cell states through the lens of single cells
AL MacLean, T Hong, Q Nie
Current Opinion in Systems Biology 9, 32-41, 2018
162018
Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis
B Lambert, AL MacLean, AG Fletcher, AN Combes, MH Little, HM Byrne
Journal of mathematical biology 76 (7), 1673-1697, 2018
152018
Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia
HL Crowell, AL MacLean, MPH Stumpf
Journal of theoretical biology 401, 43-53, 2016
142016
Concise review: stem cell population biology: insights from hematopoiesis
AL MacLean, C Lo Celso, MPH Stumpf
Stem cells 35 (1), 80-88, 2017
132017
Cellular population dynamics control the robustness of the stem cell niche
AL MacLean, PDW Kirk, MPH Stumpf
Biology open 4 (11), 1420-1426, 2015
132015
Conditional Random Matrix Ensembles and the Stability of Dynamical Systems
P Kirk, DMY Rolando, AL MacLean, MPH Stumpf
New Journal of Physics 17 (8), 083025, 2015
132015
A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions
T Peng, L Liu, AL MacLean, CW Wong, W Zhao, Q Nie
BMC systems biology 11 (1), 55, 2017
112017
Mathematical and statistical techniques for systems medicine: the Wnt signaling pathway as a case study
AL MacLean, HA Harrington, MPH Stumpf, HM Byrne
Systems Medicine, 405-439, 2016
102016
Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points
ML Vainieri, AM Blagborough, AL MacLean, MLR Haltalli, N Ruivo, ...
Open biology 6 (6), 160038, 2016
82016
An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation
D Haensel, P Sun, AL MacLean, X Ma, Y Zhou, MP Stemmler, S Brabletz, ...
EMBO reports 20 (1), 2019
72019
Cell lineage and communication network inference via optimization for single-cell transcriptomics
S Wang, M Karikomi, AL MacLean, Q Nie
Nucleic acids research 47 (11), e66-e66, 2019
42019
Epithelial-mesenchymal transition in metastatic cancer cell populations affects tumor dormancy in a simple mathematical model
A MacLean, H Harrington, M Stumpf, M Hansen
Biomedicines 2 (4), 384-402, 2014
42014
Single cell phenotyping reveals heterogeneity among hematopoietic stem cells following infection
AL MacLean, MA Smith, J Liepe, A Sim, R Khorshed, NM Rashidi, ...
Stem Cells 35 (11), 2292-2304, 2017
32017
Defining epidermal basal cell states during skin homeostasis and wound healing using single-cell transcriptomics
D Haensel, S Jin, R Cinco, P Sun, QH Nguyen, Z Cang, M Dragan, ...
CELL-REPORTS-D-19-03724, 2019
2019
Single cell transcriptomics of human epidermis reveals basal stem cell transition states
S Wang, ML Drummond, CF Guerrero-Juarez, E Tarapore, AL MacLean, ...
bioRxiv, 784579, 2019
2019
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Articles 1–20