Kaleeckal G. Harikumar
Kaleeckal G. Harikumar
Mayo clinic: Assistant Professor
Verified email at mayo.edu
TitleCited byYear
Dependence of critical micelle concentration of a zwitterionic detergent on ionic strength: implications in receptor solubilization
A Chattopadhyay, KG Harikumar
FEBS letters 391 (1-2), 199-202, 1996
Transmembrane segment IV contributes a functionally important interface for oligomerization of the Class II G protein-coupled secretin receptor
KG Harikumar, DI Pinon, LJ Miller
Journal of Biological Chemistry 282 (42), 30363-30372, 2007
Differential effects of modification of membrane cholesterol and sphingolipids on the conformation, function, and trafficking of the G protein-coupled cholecystokinin receptor
KG Harikumar, V Puri, RD Singh, K Hanada, RE Pagano, LJ Miller
Journal of Biological Chemistry 280 (3), 2176-2185, 2005
Heterodimerization of type A and B cholecystokinin receptors enhance signaling and promote cell growth
ZJ Cheng, KG Harikumar, EL Holicky, LJ Miller
Journal of Biological Chemistry 278 (52), 52972-52979, 2003
G-protein-dependent cell surface dynamics of the human serotonin1A receptor tagged to yellow fluorescent protein
TJ Pucadyil, S Kalipatnapu, KG Harikumar, N Rangaraj, SS Karnik, ...
Biochemistry 43 (50), 15852-15862, 2004
Constitutive formation of oligomeric complexes between family BG protein-coupled vasoactive intestinal polypeptide and secretin receptors
KG Harikumar, MM Morfis, CS Lisenbee, PM Sexton, LJ Miller
Molecular pharmacology 69 (1), 363-373, 2006
Structure and function of Norrin in assembly and activation of a Frizzled 4–Lrp5/6 complex
J Ke, KG Harikumar, C Erice, C Chen, X Gu, L Wang, N Parker, Z Cheng, ...
Genes & development 27 (21), 2305-2319, 2013
Dimeric arrangement of the parathyroid hormone receptor and a structural mechanism for ligand-induced dissociation
AA Pioszak, KG Harikumar, NR Parker, LJ Miller, HE Xu
Journal of biological chemistry 285 (16), 12435-12444, 2010
Induced Association of μ Opioid (MOP) and Type 2 Cholecystokinin (CCK2) Receptors by Novel Bivalent Ligands
Y Zheng, E Akgun, KG Harikumar, J Hopson, MD Powers, MM Lunzer, ...
Journal of medicinal chemistry 52 (2), 247-258, 2008
Environment and mobility of a series of fluorescent reporters at the amino terminus of structurally related peptide agonists and antagonists bound to the cholecystokinin receptor
KG Harikumar, DI Pinon, WS Wessels, FG Prendergast, LJ Miller
Journal of Biological Chemistry 277 (21), 18552-18560, 2002
Role of cholesterol in ligand binding and G-protein coupling of serotonin1A receptors solubilized from bovine hippocampus
A Chattopadhyay, M Jafurulla, S Kalipatnapu, TJ Pucadyil, KG Harikumar
Biochemical and biophysical research communications 327 (4), 1036-1041, 2005
Pattern of intra-family hetero-oligomerization involving the G-protein-coupled secretin receptor
KG Harikumar, MM Morfis, PM Sexton, LJ Miller
Journal of molecular neuroscience 36 (1-3), 279-285, 2008
Functional importance of a structurally distinct homodimeric complex of the family BG protein-coupled secretin receptor
F Gao, KG Harikumar, M Dong, PCH Lam, PM Sexton, A Christopoulos, ...
Molecular pharmacology 76 (2), 264-274, 2009
Differential discrimination of G‐protein coupling of serotonin1A receptors from bovine hippocampus by an agonist and an antagonist
KG Harikumar, A Chattopadhyay
FEBS letters 457 (3), 389-392, 1999
Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allostery
KG Harikumar, D Wootten, DI Pinon, C Koole, AM Ball, SGB Furness, ...
Proceedings of the National Academy of Sciences 109 (45), 18607-18612, 2012
Molecular basis of association of receptor activity-modifying protein 3 with the family BG protein-coupled secretin receptor
KG Harikumar, J Simms, G Christopoulos, PM Sexton, LJ Miller
Biochemistry 48 (49), 11773-11785, 2009
Dimerization in the absence of higher-order oligomerization of the G protein-coupled secretin receptor
KG Harikumar, RM Happs, LJ Miller
Biochimica et Biophysica Acta (BBA)-Biomembranes 1778 (11), 2555-2563, 2008
Distinct molecular mechanisms for agonist peptide binding to types A and B cholecystokinin receptors demonstrated using fluorescence spectroscopy
KG Harikumar, J Clain, DI Pinon, M Dong, LJ Miller
Journal of Biological Chemistry 280 (2), 1044-1050, 2005
Metal Ion and Guanine Nucleotide Modulations of Agonist Interaction in G-Protein-Coupled Serotonin1A Receptors from Bovine Hippocampus
KG Harikumar, A Chattopadhyay
Cellular and molecular neurobiology 18 (5), 535-553, 1998
Differential sensitivity of types 1 and 2 cholecystokinin receptors to membrane cholesterol
RM Potter, KG Harikumar, SV Wu, LJ Miller
Journal of lipid research 53 (1), 137-148, 2012
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