| SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate D Olagnier, E Farahani, J Thyrsted, J Blay-Cadanet, A Herengt, M Idorn, ... Nature communications 11 (1), 4938, 2020 | 345 | 2020 |
| La-related protein 1 (LARP1) represses terminal oligopyrimidine (TOP) mRNA translation downstream of mTOR complex 1 (mTORC1) BD Fonseca, C Zakaria, JJ Jia, TE Graber, Y Svitkin, S Tahmasebi, ... Journal of Biological Chemistry 290 (26), 15996-16020, 2015 | 263 | 2015 |
| S6K-STING interaction regulates cytosolic DNA–mediated activation of the transcription factor IRF3 F Wang, T Alain, KJ Szretter, K Stephenson, JG Pol, MJ Atherton, ... Nature immunology 17 (5), 514-522, 2016 | 86 | 2016 |
| mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1 JJ Jia, RM Lahr, MT Solgaard, BJ Moraes, R Pointet, AD Yang, G Celucci, ... Nucleic acids research 49 (6), 3461-3489, 2021 | 63 | 2021 |
| Near real-time determination of B. 1.1. 7 in proportion to total SARS-CoV-2 viral load in wastewater using an allele-specific primer extension PCR strategy TE Graber, É Mercier, K Bhatnagar, M Fuzzen, PM D'Aoust, HD Hoang, ... Water research 205, 117681, 2021 | 50 | 2021 |
| Battling for ribosomes: translational control at the forefront of the antiviral response HD Hoang, TE Graber, T Alain Journal of molecular biology 430 (14), 1965-1992, 2018 | 41 | 2018 |
| Modulating endoplasmic reticulum-Golgi cargo receptors for improving secretion of carrier-fused heterologous proteins in the filamentous fungus Aspergillus oryzae HD Hoang, J Maruyama, K Kitamoto Applied and Environmental Microbiology 81 (2), 533-543, 2015 | 34 | 2015 |
| UPF1 governs synaptic plasticity through association with a STAU2 RNA granule TE Graber, E Freemantle, MN Anadolu, S Hébert-Seropian, RL MacAdam, ... Journal of Neuroscience 37 (38), 9116-9131, 2017 | 31 | 2017 |
| Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis C Zakaria, P Sean, HD Hoang, LP Leroux, M Watson, ST Workenhe, ... PLoS Pathogens 14 (8), e1007264, 2018 | 27 | 2018 |
| Emerging translation strategies during virus–host interaction HD Hoang, S Neault, A Pelin, T Alain Wiley Interdisciplinary Reviews: RNA 12 (1), e1619, 2021 | 21 | 2021 |
| miR-223 exerts translational control of proatherogenic genes in macrophages MA Nguyen, HD Hoang, A Rasheed, AC Duchez, H Wyatt, ML Cottee, ... Circulation Research 131 (1), 42-58, 2022 | 18 | 2022 |
| Induction of an alternative mRNA 5′ leader enhances translation of the ciliopathy gene Inpp5e and resistance to oncolytic virus infection HD Hoang, TE Graber, JJ Jia, N Vaidya, VH Gilchrist, X Xiang, W Li, ... Cell Reports 29 (12), 4010-4023. e5, 2019 | 15 | 2019 |
| LARP1 is a major phosphorylation substrate of mTORC1 BD Fonseca, JJ Jia, AK Hollensen, R Pointet, HD Hoang, MR Niklaus, ... BioRxiv, 491274, 2018 | 15 | 2018 |
| La-related protein 1 (LARP1) represses terminal oligopyrimidine (TOP) mRNA translation downstream of mTOR complex 1 (mTORC1) J Biol Chem. 2015; 290 (26): 15996–16020. doi: 10 … BD Fonseca, C Zakaria, JJ Jia, TE Graber, Y Svitkin, S Tahmasebi, ... M114 621730, 0 | 13 | |
| Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies T Azad, R Rezaei, R Singaravelu, A Pelin, S Boulton, J Petryk, KA Onsu, ... Nature communications 14 (1), 3035, 2023 | 11 | 2023 |
| An allele-specific primer extension assay to quantify the proportion of B. 1.1. 7-specific SARS-CoV-2 RNA in wastewater TE Graber, K Bhatnagar, E Mercier, M Fuzzen, PM D'Aoust, HD Hoang, ... | 8 | 2021 |
| Author Correction: SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate D Olagnier, E Farahani, J Thyrsted, J Blay-Cadanet, A Herengt, M Idorn, ... Nature Communications 11, 2020 | 8 | 2020 |
| Evolution of TOR and translation control BD Fonseca, TE Graber, HD Hoang, A González, AA Soukas, ... Evolution of the protein synthesis machinery and its regulation, 327-411, 2016 | 8 | 2016 |
| Quercetin induces pannexin 1 expression via an alternative transcript with a translationally active 5′ leader in rhabdomyosarcoma X Xiang, HD Hoang, VH Gilchrist, S Langlois, T Alain, KN Cowan Oncogenesis 11 (1), 9, 2022 | 5 | 2022 |
| CARMAL Is a Long Non-coding RNA Locus That Regulates MFGE8 Expression S Soubeyrand, M Nikpay, P Lau, A Turner, HD Hoang, T Alain, ... Frontiers in Genetics 11, 631, 2020 | 3 | 2020 |
Tommy AlainChildren's Hospital of Eastern Ontario Research Institute and University of OttawaVerified email at arc.cheo.ca
