|BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy|
RC Koya, S Mok, N Otte, KJ Blacketor, B Comin-Anduix, PC Tumeh, ...
Cancer research 72 (16), 3928-3937, 2012
|Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death|
NA Graham, M Tahmasian, B Kohli, E Komisopoulou, M Zhu, I Vivanco, ...
Molecular systems biology 8 (1), 589, 2012
|Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication|
M Thai, NA Graham, D Braas, M Nehil, E Komisopoulou, SK Kurdistani, ...
Cell metabolism 19 (4), 694-701, 2014
|Phosphoproteome integration reveals patient-specific networks in prostate cancer|
JM Drake, EO Paull, NA Graham, JK Lee, BA Smith, B Titz, T Stoyanova, ...
Cell 166 (4), 1041-1054, 2016
|Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression|
JM Drake, NA Graham, T Stoyanova, A Sedghi, AS Goldstein, H Cai, ...
Proceedings of the National Academy of Sciences 109 (5), 1643-1648, 2012
|MCT1 modulates cancer cell pyruvate export and growth of tumors that co-express MCT1 and MCT4|
CS Hong, NA Graham, W Gu, CE Camacho, V Mah, EL Maresh, M Alavi, ...
Cell reports 14 (7), 1590-1601, 2016
|Lactate dehydrogenase activity drives hair follicle stem cell activation|
A Flores, J Schell, AS Krall, D Jelinek, M Miranda, M Grigorian, D Braas, ...
Nature cell biology 19 (9), 1017-1026, 2017
|DNA-PKcs-mediated transcriptional regulation drives prostate cancer progression and metastasis|
JF Goodwin, V Kothari, JM Drake, S Zhao, E Dylgjeri, JL Dean, ...
Cancer cell 28 (1), 97-113, 2015
|A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens|
J Sun, MD Masterman-Smith, NA Graham, J Jiao, J Mottahedeh, DR Laks, ...
Cancer research 70 (15), 6128-6138, 2010
|Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets|
JM Drake, NA Graham, JK Lee, T Stoyanova, CM Faltermeier, S Sud, ...
Proceedings of the National Academy of Sciences 110 (49), E4762-E4769, 2013
|Tunable interplay between epidermal growth factor and cell–cell contact governs the spatial dynamics of epithelial growth|
JH Kim, K Kushiro, NA Graham, AR Asthagiri
Proceedings of the National Academy of Sciences 106 (27), 11149-11153, 2009
|Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures|
NA Graham, A Minasyan, A Lomova, A Cass, NG Balanis, M Friedman, ...
Molecular systems biology 13 (2), 914, 2017
|Epidermal growth factor-mediated T-cell factor/lymphoid enhancer factor transcriptional activity is essential but not sufficient for cell cycle progression in nontransformed …|
NA Graham, AR Asthagiri
Journal of Biological Chemistry 279 (22), 23517-23524, 2004
|The impact of ex vivo clinical grade activation protocols on human T cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy|
PC Tumeh, RC Koya, T Chodon, NA Graham, TG Graeber, ...
Journal of immunotherapy (Hagerstown, Md.: 1997) 33 (8), 759, 2010
|Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells|
A Delfarah, S Parrish, JA Junge, J Yang, F Seo, S Li, J Mac, P Wang, ...
Journal of Biological Chemistry 294 (27), 10564-10578, 2019
|Deep protein methylation profiling by combined chemical and immunoaffinity approaches reveals novel PRMT1 targets|
NG Hartel, B Chew, J Qin, J Xu, NA Graham
Molecular & Cellular Proteomics 18 (11), 2149-2164, 2019
|Automated quantitative analysis of epithelial cell scatter|
MD Pope, NA Graham, BK Huang, AR Asthagiri
Cell adhesion & migration 2 (2), 110-116, 2008
|A synthetic lethal drug combination mimics glucose deprivation–induced cancer cell death in the presence of glucose|
JH Joly, A Delfarah, PS Phung, S Parrish, NA Graham
Journal of Biological Chemistry 295 (5), 1350-1365, 2020
|Computational model of chimeric antigen receptors explains site-specific phosphorylation kinetics|
JA Rohrs, D Zheng, NA Graham, P Wang, SD Finley
Biophysical journal 115 (6), 1116-1129, 2018
|Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin|
A Flores, S Sandoval-Gonzalez, R Takahashi, A Krall, L Sathe, L Wei, ...
Nature communications 10 (1), 1-14, 2019