|RNA polymerase III transcription factor TFIIIC2 is overexpressed in ovarian tumors|
AG Winter, G Sourvinos, SJ Allison, K Tosh, PH Scott, DA Spandidos, ...
Proceedings of the National Academy of Sciences 97 (23), 12619-12624, 2000
|JNK2-dependent regulation of SIRT1 protein stability|
J Ford, S Ahmed, S Allison, M Jiang, J Milner
Cell Cycle 7 (19), 3091-3097, 2008
|SIRT3 is pro-apoptotic and participates in distinct basal apoptotic pathways|
SJ Allison, JO Milner
Cell Cycle 6 (21), 2669-2677, 2007
|CK2 forms a stable complex with TFIIIB and activates RNA polymerase III transcription in human cells|
IM Johnston, SJ Allison, JP Morton, L Schramm, PH Scott, RJ White
Molecular and cellular biology 22 (11), 3757-3768, 2002
|Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD (H)-dependent and (ii) p53-independent pathways|
SJ Allison, JRP Knight, C Granchi, R Rani, F Minutolo, J Milner, ...
Oncogenesis 3 (5), e102-e102, 2014
|Retinoblastoma protein disrupts interactions required for RNA polymerase III transcription|
JE Sutcliffe, TRP Brown, SJ Allison, PH Scott, RJ White
Molecular and cellular biology 20 (24), 9192-9202, 2000
|RNA polymerase III transcription factor IIIB is a target for repression by pocket proteins p107 and p130|
JE Sutcliffe, CA Cairns, A McLees, SJ Allison, K Tosh, RJ White
Molecular and Cellular Biology 19 (6), 4255-4261, 1999
|Remodelling chromatin on a global scale: a novel protective function of p53|
SJ Allison, J Milner
Carcinogenesis 25 (9), 1551-1557, 2004
|Hypoxia-sensitive metal β-ketoiminato complexes showing induced single-strand DNA breaks and cancer cell death by apoptosis|
RM Lord, AJ Hebden, CM Pask, IR Henderson, SJ Allison, SL Shepherd, ...
Journal of Medicinal Chemistry 58 (12), 4940-4953, 2015
|Loss of p53 has site-specific effects on histone H3 modification, including serine 10 phosphorylation important for maintenance of ploidy|
SJ Allison, J Milner
Cancer research 63 (20), 6674-6679, 2003
|SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53|
CJ Lynch, ZH Shah, SJ Allison, SU Ahmed, J Ford, LJ Warnock, H Li, ...
PloS one 5 (10), e13502, 2010
|Development and characterization of a microfluidic model of the tumour microenvironment|
JM Ayuso, M Virumbrales-Muņoz, A Lacueva, PM Lanuza, ...
Scientific reports 6 (1), 1-16, 2016
|Oncogenic viral protein HPV E7 up-regulates the SIRT1 longevity protein in human cervical cancer cells|
SJ Allison, M Jiang, J Milner
Aging 1 (3), 316, 2009
|Anticancer metallohelices: nanomolar potency and high selectivity|
RA Kaner, SJ Allison, AD Faulkner, RM Phillips, DI Roper, SL Shepherd, ...
Chemical science 7 (2), 951-958, 2016
|Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands|
SJ Allison, M Sadiq, E Baronou, PA Cooper, C Dunnill, NT Georgopoulos, ...
Cancer Letters 403, 98-107, 2017
|A deacetylase-deficient SIRT1 variant opposes full-length SIRT1 in regulating tumor suppressor p53 and governs expression of cancer-related genes|
ZH Shah, SU Ahmed, JR Ford, SJ Allison, JRP Knight, J Milner
Molecular and cellular biology 32 (3), 704-716, 2012
|Hypoxia modulates the activity of a series of clinically approved tyrosine kinase inhibitors|
M Ahmadi, Z Ahmadihosseini, SJ Allison, S Begum, K Rockley, M Sadiq, ...
British journal of pharmacology 171 (1), 224-236, 2014
|Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment|
SM Elkashef, SJ Allison, M Sadiq, HA Basheer, GR Morais, PM Loadman, ...
Scientific reports 6, 33026, 2016
|Increasing anti-cancer activity with longer tether lengths of group 9 Cp* complexes|
SJ Lucas, RM Lord, AM Basri, SJ Allison, RM Phillips, AJ Blacker, ...
Dalton Transactions 45 (16), 6812-6815, 2016
|KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice|
ES Polson, VB Kuchler, C Abbosh, EM Ross, RK Mathew, HA Beard, ...
Science translational medicine 10 (454), 2018