Charles Glabe
Charles Glabe
Verified email at uci.edu
TitleCited byYear
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
R Kayed, E Head, JL Thompson, TM McIntire, SC Milton, CW Cotman, ...
Science 300 (5618), 486-489, 2003
39132003
A specific amyloid-β protein assembly in the brain impairs memory
S Lesné, MT Koh, L Kotilinek, R Kayed, CG Glabe, A Yang, M Gallagher, ...
Nature 440 (7082), 352, 2006
28422006
Curcumin inhibits formation of amyloid β oligomers and fibrils, binds plaques, and reduces amyloid in vivo
F Yang, GP Lim, AN Begum, OJ Ubeda, MR Simmons, SS Ambegaokar, ...
Journal of Biological Chemistry 280 (7), 5892-5901, 2005
20172005
Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state
CJ Pike, D Burdick, AJ Walencewicz, CG Glabe, CW Cotman
Journal of Neuroscience 13 (4), 1676-1687, 1993
16951993
Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs.
D Burdick, B Soreghan, M Kwon, J Kosmoski, M Knauer, A Henschen, ...
Journal of Biological Chemistry 267 (1), 546-554, 1992
11521992
In vitro aging of ß-amyloid protein causes peptide aggregation and neurotoxicity
CJ Pike, AJ Walencewicz, CG Glabe, CW Cotman
Brain research 563 (1-2), 311-314, 1991
10021991
Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers
A Demuro, E Mina, R Kayed, SC Milton, I Parker, CG Glabe
Journal of Biological Chemistry 280 (17), 17294-17300, 2005
9892005
Cu (II) potentiation of Alzheimer Aβ neurotoxicity correlation with cell-free hydrogen peroxide production and metal reduction
X Huang, MP Cuajungco, CS Atwood, MA Hartshorn, JDA Tyndall, ...
Journal of Biological Chemistry 274 (52), 37111-37116, 1999
8861999
Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases
R Kayed, Y Sokolov, B Edmonds, TM McIntire, SC Milton, JE Hall, ...
Journal of Biological Chemistry 279 (45), 46363-46366, 2004
8832004
Structure‐activity analyses of β‐amyloid peptides: contributions of the β25–35 region to aggregation and neurotoxicity
CJ Pike, AJ Walencewicz‐Wasserman, J Kosmoski, DH Cribbs, CG Glabe, ...
Journal of neurochemistry 64 (1), 253-265, 1995
8261995
Type 2 innate lymphoid cells control eosinophil homeostasis
JC Nussbaum, SJ Van Dyken, J Von Moltke, LE Cheng, A Mohapatra, ...
Nature 502 (7470), 245, 2013
791*2013
Structural classification of toxic amyloid oligomers
CG Glabe
Journal of Biological Chemistry 283 (44), 29639-29643, 2008
7342008
Small molecule inhibitors of aggregation indicate that amyloid β oligomerization and fibrillization pathways are independent and distinct
M Necula, R Kayed, S Milton, CG Glabe
Journal of Biological Chemistry 282 (14), 10311-10324, 2007
6902007
Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers
R Kayed, E Head, F Sarsoza, T Saing, CW Cotman, M Necula, L Margol, ...
Molecular neurodegeneration 2 (1), 18, 2007
5882007
Different conformations of amyloid β induce neurotoxicity by distinct mechanisms in human cortical neurons
A Deshpande, E Mina, C Glabe, J Busciglio
Journal of Neuroscience 26 (22), 6011-6018, 2006
5582006
Common mechanisms of amyloid oligomer pathogenesis in degenerative disease
CG Glabe
Neurobiology of aging 27 (4), 570-575, 2006
5362006
Temporal profile of amyloid-β (Aβ) oligomerization in an in vivo model of Alzheimer disease A link between Aβ and tau pathology
S Oddo, A Caccamo, L Tran, MP Lambert, CG Glabe, WL Klein, ...
Journal of Biological Chemistry 281 (3), 1599-1604, 2006
4252006
Atomic view of a toxic amyloid small oligomer
A Laganowsky, C Liu, MR Sawaya, JP Whitelegge, J Park, M Zhao, ...
Science 335 (6073), 1228-1231, 2012
4212012
Biosynthetic site-specific incorporation of a non-natural amino acid into a polypeptide
JD Bain, ES Diala, CG Glabe, TA Dix, AR Chamberlin
Journal of the American Chemical Society 111 (20), 8013-8014, 1989
4191989
Structural and dynamic features of Alzheimer's Aβ peptide in amyloid fibrils studied by site-directed spin labeling
M Török, S Milton, R Kayed, P Wu, T McIntire, CG Glabe, R Langen
Journal of Biological Chemistry 277 (43), 40810-40815, 2002
3932002
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Articles 1–20