|Fracture healing as a post‐natal developmental process: molecular, spatial, and temporal aspects of its regulation|
LC Gerstenfeld, DM Cullinane, GL Barnes, DT Graves, TA Einhorn
Journal of cellular biochemistry 88 (5), 873-884, 2003
|Differential temporal expression of members of the transforming growth factor β superfamily during murine fracture healing|
TJ Cho, LC Gerstenfeld, TA Einhorn
Journal of bone and mineral research 17 (3), 513-520, 2002
|BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing|
K Tsuji, A Bandyopadhyay, BD Harfe, K Cox, S Kakar, L Gerstenfeld, ...
Nature genetics 38 (12), 1424-1429, 2006
|Fracture healing: mechanisms and interventions|
TA Einhorn, LC Gerstenfeld
Nature Reviews Rheumatology 11 (1), 45, 2015
|Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis|
ZS Ai-Aql, AS Alagl, DT Graves, LC Gerstenfeld, TA Einhorn
Journal of dental research 87 (2), 107-118, 2008
|The hypoxia-inducible factor α pathway couples angiogenesis to osteogenesis during skeletal development|
Y Wang, C Wan, L Deng, X Liu, X Cao, SR Gilbert, ML Bouxsein, ...
The Journal of clinical investigation 117 (6), 1616-1626, 2007
|Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cells|
MA Aronow, LC Gerstenfeld, TA Owen, MS Tassinari, GS Stein, JB Lian
Journal of cellular physiology 143 (2), 213-221, 1990
|Growth factor regulation of fracture repair|
GL Barnes, PJ Kostenuik, LC Gerstenfeld, TA Einhorn
Journal of Bone and Mineral Research 14 (11), 1805-1815, 1999
|Expression of osteoprotegerin, receptor activator of NF‐κB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing|
T Kon, TJ Cho, T Aizawa, M Yamazaki, N Nooh, D Graves, LC Gerstenfeld, ...
Journal of Bone and Mineral Research 16 (6), 1004-1014, 2001
|Activation of the hypoxia-inducible factor-1α pathway accelerates bone regeneration|
C Wan, SR Gilbert, Y Wang, X Cao, X Shen, G Ramaswamy, ...
Proceedings of the National Academy of Sciences 105 (2), 686-691, 2008
|Expression of differentiated function by mineralizing cultures of chicken osteoblasts|
LC Gerstenfeld, SD Chipman, J Glowacki, JB Lian
Developmental biology 122 (1), 49-60, 1987
|Impaired fracture healing in the absence of TNF‐α signaling: The role of TNF‐α in endochondral cartilage resorption|
LC Gerstenfeld, TJ Cho, T Kon, T Aizawa, A Tsay, J Fitch, GL Barnes, ...
Journal of Bone and Mineral Research 18 (9), 1584-1592, 2003
|Diabetes interferes with the bone formation by affecting the expression of transcription factors that regulate osteoblast differentiation|
H Lu, D Kraut, LC Gerstenfeld, DT Graves
Endocrinology 144 (1), 346-352, 2003
|Differential inhibition of fracture healing by non‐selective and cyclooxygenase‐2 selective non‐steroidal anti‐inflammatory drugs|
LC Gerstenfeld, M Thiede, K Seibert, C Mielke, D Phippard, B Svagr, ...
Journal of orthopaedic research 21 (4), 670-675, 2003
|Enhancement of experimental fracture-healing by systemic administration of recombinant human parathyroid hormone (PTH 1-34)|
YM Alkhiary, LC Gerstenfeld, E Krall, M Westmore, M Sato, BH Mitlak, ...
JBJS 87 (4), 731-741, 2005
|Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways|
M Alikhani, Z Alikhani, C Boyd, CM MacLellan, M Raptis, R Liu, N Pischon, ...
Bone 40 (2), 345-353, 2007
|Diabetes causes decreased osteoclastogenesis, reduced bone formation, and enhanced apoptosis of osteoblastic cells in bacteria stimulated bone loss|
H He, R Liu, T Desta, C Leone, LC Gerstenfeld, DT Graves
Endocrinology 145 (1), 447-452, 2004
|Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity|
RA Kayal, D Tsatsas, MA Bauer, B Allen, MO Al‐Sebaei, S Kakar, ...
Journal of Bone and Mineral Research 22 (4), 560-568, 2007
|BMP treatment of C3H10T1/2 mesenchymal stem cells induces both chondrogenesis and osteogenesis|
CM Shea, CM Edgar, TA Einhorn, LC Gerstenfeld
Journal of cellular biochemistry 90 (6), 1112-1127, 2003
|Expression of bone‐specific genes by hypertrophic chondrocytes: Implications of the complex functions of the hypertrophic chondrocyte during endochondral bone development|
LC Gerstenfeld, FD Shapiro
Journal of cellular biochemistry 62 (1), 1-9, 1996